Juergen Weber

US Patent:

7309717, Dec 18, 2007

Filed:

Jun 15, 2004

Appl. No.:

10/867602

Inventors:

Jeonghan Park - Whippany NJ, US
Anantha Sudhakar - East Brunswick NJ, US
George S. Wong - Summit NJ, US
Minzhang Chen - Plainsboro NJ, US
Juergen Weber - East Windsor NJ, US
Xiaojing Yang - Waterford CT, US
Ingyu Jeon - Fanwood NJ, US
Ramani R. Raghavan - Edison NJ, US
Maria Tamarez - Rahway NJ, US
Weidong Tong - Mountainside NJ, US
Eugene J. Vater - Lyndhurst NJ, US

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

A61K 31/21
C07D 209/52

US Classification:

514412, 548452

Abstract:

In one embodiment, the present application relates to a process of making a compound of formula I.

US Patent:

7326795, Feb 5, 2008

Filed:

Jun 15, 2004

Appl. No.:

10/867600

Inventors:

Anantha Sudhakar - East Brunswick NJ, US
Vilas Dahanukar - Hyderabad, IN
Ilia A. Zavialov - East Windsor NJ, US
Cecilia Orr - Clark NJ, US
Hoa N. Nguyen - Dayton NJ, US
Juergen Weber - East Windsor NJ, US
Ingyu Jeon - Fanwood NJ, US
Minzhang Chen - Plainsboro NJ, US
Michael D. Green - Willingboro NJ, US
George S. Wong - Summit NJ, US
Jeonghan Park - Whippany NJ, US
Tetsuo Iwama - Scotch Plains NJ, US

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

C07D 209/52
C07C 233/08

US Classification:

548515, 564199

Abstract:

In one embodiment, the present application relates to a process of making a compound of formula I:.

US Patent:

7569705, Aug 4, 2009

Filed:

Nov 6, 2007

Appl. No.:

11/982875

Inventors:

Jeonghan Park - Whippany NJ, US
Anantha R Sudhakar - Fremont CA, US
George S. K. Wong - Summit NJ, US
Minzhang Chen - Plainsboro NJ, US
Juergen Weber - East Windsor NJ, US
Xiaojing Yang - Waterford CT, US
Ingyu Jeon - Fanwood NJ, US
Ramani R Raghavan - Lexington MA, US
Maria Tamarez - Rahway NJ, US
Weidong Tong - Mountainside NJ, US
Eugene J. Vater - Lyndhurst NJ, US

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

C07D 209/52

US Classification:

548515

Abstract:

In one embodiment, the present application relates to a process of making a compound of formula I.

US Patent:

7723531, May 25, 2010

Filed:

Dec 20, 2006

Appl. No.:

11/792770

Inventors:

George Wu - Basking Ridge NJ, US
Frank X. Chen - Plainsboro NJ, US
Paitoon Rashatasakhon - Samutsakhon, TH
Jeffrey M. Eckert - Hazlet NJ, US
George S. K. Wong - Summit NJ, US
Hong-Chang Lee - Livingston NJ, US
Nolan C. Erickson - West Orange NJ, US
Jennifer Ann Vance - Scotch Plains NJ, US
Peter C. Nirchio - Lebanon NJ, US
Juergen Weber - East Windsor NJ, US
David Jieh-Shyh Tsai - Warren NJ, US
Nanfei Zou - East Brunswick NJ, US

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

C07D 209/52

US Classification:

548515, 548452

Abstract:

The present invention provides for a process for preparing racemic methyl 6,6-dimethyl-3-azabicyclo[3,1,0]hexane-2-carboxylate, its corresponding salt: (2S, 3R, 4S)-methyl 6,6-dimethyl-3-azabicyclo[3,1,0]hexane-2-carboxylate di-p-toluoyl-D-tartaric acid (“D-DTTA”) salt or a (2R, 3S, 4R)-methyl 6,6-dimethyl-3-azabicyclo[3,1,0]hexane-2-carboxylate di-p-toluoyl-L-tartaric acid salt (“L-DTTA”) in a high enantiomeric excess. This invention also provides for a process for preparing a (2S, 3R, 4S)-methyl 6,6-dimethyl-3-azabicyclo[3,1,0]hexane-2-carboxylate dibenzoyl-D-tartaric acid (“D-DBTA”) salt or a (2R, 3S, 4R)-methyl 6,6-dimethyl-3-azabicyclo[3,1,0]hexane-2-carboxylate L-tartaric acid (“L-DBTA”) salt in a high enantiomeric excess. Further, this invention provides a process for preparing intermediates II, IIB, III, IV, IV salt, V, VI, and VII.

US Patent:

7728165, Jun 1, 2010

Filed:

Jun 15, 2009

Appl. No.:

12/484461

Inventors:

Jeonghan Park - Whippany NJ, US
Anantha R Sudhakar - Fremont CA, US
George S. K. Wong - Summit NJ, US
Minzhang Chen - Plainsboro NJ, US
Juergen Weber - East Windsor NJ, US
Xiaojing Yang - Waterford CT, US
Ingyu Jeon - Fanwood NJ, US
Ramani R Raghavan - Lexington MA, US
Maria Tamarez - Rahway NJ, US
Weidong Tong - Mountainside NJ, US
Eugene J. Vater - Lyndhurst NJ, US

Assignee:

Schering Plough Corporation - Kenilworth NJ

International Classification:

C07C 69/01
C07C 211/17
C07C 235/02

US Classification:

560124, 564182, 564455

Abstract:

In one embodiment, the present application relates to a process of making a compound of formula I.

US Patent:

8198463, Jun 12, 2012

Filed:

Apr 9, 2010

Appl. No.:

12/757322

Inventors:

George Wu - Basking Ridge NJ, US
Frank X. Chen - Plainsboro NJ, US
Paitoon Rashatasakhon - Samutsakhon, TH
Jeffrey M. Eckert - Hazlet NJ, US
George S. K. Wong - Summit NJ, US
Hong-Chang Lee - Livingston NJ, US
Nolan C. Erickson - West Orange NJ, US
Jennifer Ann Vance - Scotch Plains NJ, US
Peter C. Nirchio - Lebanon NJ, US
Juergen Weber - East Windsor NJ, US
David Jieh-Shyh Tsai - Warren NJ, US
Nanfei Zou - East Brunswick NJ, US

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

C07D 209/52

US Classification:

548515, 548452

Abstract:

The present invention provides for a process for preparing racemic methyl 6,6-dimethyl-3-azabicyclo[3,1,0]hexane-2-carboxylate, its corresponding salt: (1R,2S,5S)-methyl 6,6-dimethyl-3-azabicyclo[3,1,0]hexane-2-carboxylate di-p-toluoyl-D-tartaric acid (“D-DTTA”) salt or a (1S,2R,5R)-methyl 6,6-dimethyl-3-azabicyclo[3,1,0]hexane-2-carboxylate di-p-toluoyl-L-tartaric acid salt (“L-DTTA”) in a high enantiomeric excess. This invention also provides for a process for preparing a (1R,2S,5S)-methyl 6,6-dimethyl-3-azabicyclo[3,1,0]hexane-2-carboxylate dibenzoyl-D-tartaric acid (“D-DBTA”) salt or a (1S,2R,5R)-methyl 6,6-dimethyl-3-azabicyclo[3,1,0]hexane-2-carboxylate L-tartaric acid (“L-DBTA”) salt in a high enantiomeric excess. Further, this invention provides a process for preparing intermediates II, IIB, III, IV, IV salt, V, VI, and VII.

US Patent:

20190348607, Nov 14, 2019

Filed:

Jul 23, 2019

Appl. No.:

16/519476

Inventors:

- Seoul, KR
Kerwin D. Dobbs - Wilmington DE, US
Adam Fennimore - Wilmington DE, US
Weiying Gao - Landenberg PA, US
Gene M. Rossi - Wilmington DE, US
Juergen Weber - Lincoln University PA, US

International Classification:

H01L 51/00
C08G 61/12

Abstract:

A hole transport copolymer having the following Formula III is disclosed herein:In some embodiments, A is a monomeric unit having Formula Ia or Formula IIa, B is a B is a monomeric unit having at least three points of attachment in the copolymer, E is the same or different at each occurrence and is selected from the group consisting of H, D, halide, alkyl, aryl, arylamino, siloxane, crosslinkable groups, deuterated alkyl, deuterated aryl, deuterated arylamino, deuterated siloxane, and deuterated crosslinkable groups, and x, y, and z are the same or different and are mole fractions, such that x+y+z=1, and x and y are non-zero.

US Patent:

20180282299, Oct 4, 2018

Filed:

Oct 16, 2015

Appl. No.:

15/518262

Inventors:

- Wilmington DE, US
Juergen Weber - Lincoln University PA, US

International Classification:

C07D 401/10
C07D 403/10
C07D 413/10
C07D 401/14
C07D 417/10
C07D 209/86
H01L 51/00
H01L 51/50

Abstract:

There is provided a compound having Formula I, Formula II, Formula III, Formula IV, Formula V, or Formula VI: