Julius J Knowles

Address:

80 Black Oak Rd, Weston, MA 02493

Phone:

7813735811

VIN:

JTJBC1BA6B2044441

Make:

LEXUS

Model:

RX 450H

Year:

2011

US Patent:

7569230, Aug 4, 2009

Filed:

Dec 15, 2006

Appl. No.:

11/611504

Inventors:

Andrew X Chen - San Diego CA, US
Julius Knowles - Del Mar CA, US
Eckard Weber - San Diego CA, US

Assignee:

Novalar Pharmaceuticals, Inc. - San Diego CA

International Classification:

A61K 9/08
A61K 31/417
A61K 31/497
A61K 47/12
A61K 47/16
A61K 47/26

US Classification:

424400, 51425216, 514401, 514818

Abstract:

The present invention provides compositions and stable liquid formulations comprising alpha adrenergic receptor antagonists and use thereof for increasing blood flow. In one embodiment, the stable liquid formulations of this invention are useful for reversing the effects of an anesthetic agent, preferably a long-lasting local anesthetic agent administered in conjunction with an alpha adrenergic receptor agonist.

US Patent:

7575757, Aug 18, 2009

Filed:

Mar 18, 2005

Appl. No.:

11/082968

Inventors:

Andrew X. Chen - San Diego CA, US
Julius Knowles - Del Mar CA, US
Eckard Weber - San Diego CA, US

Assignee:

Novalar Pharmaceuticals, Inc. - San Diego CA

International Classification:

A61K 9/08
A61K 31/417
A61K 31/497
A61K 47/12
A61K 47/16
A61K 47/26

US Classification:

424400, 51425216, 514401, 514818

Abstract:

The present invention provides compositions and stable liquid formulations comprising alpha adrenergic receptor antagonists and use thereof for increasing blood flow. In one embodiment, the stable liquid formulations of this invention are useful for reversing the effects of an anesthetic agent, preferably a long-lasting local anesthetic agent administered in conjunction with an alpha adrenergic receptor agonist.

US Patent:

20040044019, Mar 4, 2004

Filed:

Jun 20, 2003

Appl. No.:

10/465810

Inventors:

Andrew Chen - San Diego CA, US
Julius Knowles - Del Mar CA, US
Eckard Weber - San Diego CA, US

International Classification:

A61K031/4745
A61K031/4709

US Classification:

514/283000, 514/308000

Abstract:

The present invention provides compositions and stable liquid formulations comprising alpha adrenergic receptor antagonists and use thereof for increasing blood flow. In one embodiment, the stable liquid formulations of this invention are useful for reversing the effects of an anesthetic agent, preferably a long-lasting local anesthetic agent administered in conjunction with an alpha adrenergic receptor agonist.

US Patent:

20060257388, Nov 16, 2006

Filed:

May 13, 2005

Appl. No.:

11/128184

Inventors:

Julius Knowles - Del Mar CA, US

International Classification:

A61K 38/47
A61K 31/517
A61K 31/4745
A61K 31/4709
A61M 31/00

US Classification:

424094610, 514283000, 514252170, 514308000, 604500000

Abstract:

The present invention provides compositions and stable liquid formulations comprising alpha adrenergic receptor antagonists and use thereof for increasing blood flow. In one embodiment, the stable liquid formulations of this invention are useful for reversing the effects of an anesthetic agent, preferably a long-lasting local anesthetic agent administered in conjunction with an alpha adrenergic receptor agonist. The invention further relates to drug delivery systems for administering alpha adrenergic receptor antagonists.