Karl Pfenninger - Englewood CO Becky De La Houssaye - Denver CO Keith Mikule - Arvada CO Steve Helmke - Englewood CO Harry Drabkin - Denver CO
Assignee:
The Regents of the University of Colorado - Boulder CO
International Classification:
C12Q 100
US Classification:
435 4, 435325, 435375, 530300, 530350
Abstract:
The present invention provides methods of identifying and using compounds that modulate cell motility. Such compounds can be used to inhibit cancer cell metastasis or promote neurite growth and regenaration. The methods generally relate to the repellent-receptor signalling pathway that controls cellular attachment and detachment to a substratum.