Keith F Mcdaniel

US Patent:

6455571, Sep 24, 2002

Filed:

Oct 19, 1999

Appl. No.:

09/421787

Inventors:

Clarence J. Maring - Palatine IL
Yu Gui Gu - Grayslake IL
Hui-Ju Chen - Grayslake IL
Yuanwei Chen - North Haven CT
David A. Degoey - Kenosha WI
William J. Flosi - Des Plaines IL
Vincent L. Giranda - Gurnee IL
David J. Grampovnik - Waukegan IL
Warren M. Kati - Gurnee IL
Dale J. Kempf - Libertyville IL
April Kennedy - Grayslake IL
Larry L. Klein - Lake Forest IL
Allan C. Krueger - Gurnee IL
Zhen Lin - Gurnee IL
Darold L. Madigan - Elk Grove Village IL
Keith F. McDaniel - Grayslake IL
Steven W. Muchmore - Libertyville IL
Hing L. Sham - Mundelein IL
Kent D. Stewart - Gurnee IL
Vincent S. Stoll - Libertyville IL
Minghua Sun - Libertyville IL
Noah P. Tu - Gurnee IL
Frank L. Wagenaar - Gurnee IL
Gary T. Wang - Niles IL
Sheldon Wang - Grayslake IL
Paul E. Wiedeman - Deerfield IL
Yibo Xu - Ridgefield CT
Ming C. Yeung - Grayslake IL
Chen Zhao - Libertyville IL
Stephen Hanessian - Beaconsfield, CA
Malken Bayrakdarian - Verdun, CA
Xuehong Luo - Montreal, CA

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

A61K 3140

US Classification:

514423, 514422, 514397, 514365, 514374, 548532, 548533, 548518, 5483147, 548205, 548236, 548237

Abstract:

Disclosed are compounds of the formula: which are useful for inhibiting neuraminidases from disease-causing microorganisms, especially, influenza neuraminidase. Also disclosed are compositions and methods for preventing and treating diseases caused by microorganisms having a neuraminidase, processes for preparing the compounds and synthetic intermediates used in these processes.

US Patent:

6831096, Dec 14, 2004

Filed:

Sep 24, 2002

Appl. No.:

10/253152

Inventors:

Clarence J. Maring - Palatine IL
Yu Gui Gu - Grayslake IL
Hui-Ju Chen - Grayslake IL
Yuanwei Chen - North Haven CT
David A. Degoey - Kenosha WI
William J. Flosi - Des Plaines IL
Vincent L. Giranda - Gurnee IL
David J. Grampovnik - Waukegan IL
Warren M. Kati - Gurnee IL
Dale J. Kempf - Libertyville IL
April Kennedy - Boulder CO
Larry L. Klein - Lake Forest IL
Allan C. Krueger - Gurnee IL
Zhen Lin - Gurnee IL
Darold L. Madigan - Elk Grove Village IL
Keith F. McDaniel - Wauconda IL
Steven W. Muchmore - Libertyville IL
Hing L. Sham - Mundelein IL
Kent D. Stewart - Gurnee IL
Vincent S. Stoll - Libertyville IL
Minghua Sun - Libertyville IL
Noah P. Tu - Gurnee IL
Frank L. Wagenaar - Gurnee IL
Gary T. Wang - Niles IL
Sheldon Wang - Grayslake IL
Paul E. Wiedeman - Deerfield IL
Yibo Xu - New Milford CT
Ming C. Yeung - Grayslake IL
Chen Zhao - Libertyville IL
Stephen Hanessian - Beaconsfield, CA
Malken Bayrakdarian - Verdun, CA
Xuehong Luo - Montreal, CA

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

A61K 3140

US Classification:

514423

Abstract:

Disclosed are compounds of the formula: which are useful for inhibiting neuraminidases from disease-causing microorganisms, especially, influenza neuraminidase. Also disclosed are compositions and methods for preventing and treating diseases caused by microorganisms having a neuraminidase, processes for preparing the compounds and synthetic intermediates used in these processes.

US Patent:

7378414, May 27, 2008

Filed:

Aug 24, 2004

Appl. No.:

10/925072

Inventors:

Douglas K. Hutchinson - Antioch IL, US
John R. Bellettini - Antioch IL, US
David A. Betebenner - Libertyville IL, US
Richard D. Bishop - Third Lake IL, US
Thomas B. Borchardt - Kenosha WI, US
Todd D. Bosse - Chicago IL, US
Russell D. Cink - Grayslake IL, US
Charles A. Flentge - Salem WI, US
Bradley D. Gates - Mount Prospect IL, US
Brian E. Green - Wonder Lake IL, US
Mira M. Hinman - Libertyville IL, US
Peggy P. Huang - Lake Bluff IL, US
Larry L. Klein - Lake Forest IL, US
Allan C. Krueger - Gurnee IL, US
Daniel P. Larson - Oak Creek WI, US
M. Robert Leanna - Grayslake IL, US
Dachun Liu - Waukegan IL, US
Darold L. Madigan - Elk Grove Village IL, US
Keith F. McDaniel - Wauconda IL, US
John T. Randolph - Libertyville IL, US
Todd W. Rockway - Grayslake IL, US
Teresa A. Rosenberg - Gurnee IL, US
Kent D. Stewart - Gurnee IL, US
Vincent S. Stoll - Libertyville IL, US
Rolf Wagner - Gurnee IL, US
Ming C. Yeung - Grayslake IL, US

Assignee:

Abbott Laboratories - Abbott park IL

International Classification:

C07D 285/26
A61K 31/549

US Classification:

5142232, 544 12

Abstract:

Compounds having the formula.

US Patent:

7538105, May 26, 2009

Filed:

Apr 4, 2008

Appl. No.:

12/098024

Inventors:

Douglas K. Hutchinson - Antioch IL, US
John R. Bellettini - Antioch IL, US
David A. Betebenner - Libertyville IL, US
Richard D. Bishop - Third Lake IL, US
Thomas B. Borchardt - Kenosha WI, US
Todd D. Bosse - Chicago IL, US
Russell D. Cink - Grayslake IL, US
Charles A. Flentge - Salem WI, US
Bradley D. Gates - Mount Prospect IL, US
Brian E. Green - Wonder Lake IL, US
Mira M. Hinman - Libertyville IL, US
Peggy P. Huang - Lake Bluff IL, US
Larry L. Klein - Lake Forest IL, US
Allan C. Krueger - Gurnee IL, US
Daniel P. Larson - Oak Creek WI, US
M. Robert Leanna - Grayslake IL, US
Dachun Liu - Waukegan IL, US
Darold L. Madigan - Elk Grove Village IL, US
Keith F. McDaniel - Wauconda IL, US
John T. Randolph - Libertyville IL, US
Todd W. Rockway - Grayslake IL, US
Teresa A. Rosenberg - Gurnee IL, US
Kent D. Stewart - Gurnee IL, US
Vincent S. Stoll - Libertyville IL, US
Rolf Wagner - Gurnee IL, US
Ming C. Yeung - Grayslake IL, US

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

C07D 513/04
A61K 31/542

US Classification:

5142228, 544 10

Abstract:

Compounds having the formula.

US Patent:

7902203, Mar 8, 2011

Filed:

Oct 31, 2003

Appl. No.:

10/699513

Inventors:

John K. Pratt - Kenosha WI, US
David A. Betebenner - Libertyville IL, US
Pamela L. Donner - Mundelein IL, US
Brian E. Green - Wonder Lake IL, US
Dale J. Kempf - Libertyville IL, US
Keith F. McDaniel - Wauconda IL, US
Clarence J. Maring - Palatine IL, US
Vincent S. Stoll - Libertyville IL, US
Rong Zhang - Skokie IL, US
Hui-Ju Chen - Grayslake IL, US
William J. Flosi - Evanston IL, US
Larry L. Klein - Lake Forest IL, US
Allan C. Krueger - Gurnee IL, US
Dachun Liu - Waukegan IL, US
Darold L. Madigan - Elk Grove Village IL, US
Laura M. Maymon - Chicago IL, US
Todd W. Rockway - Grayslake IL, US
Kent D. Stewart - Gurnee IL, US
Ming C. Yeung - Grayslake IL, US
Qinghua Xie - Libertyville IL, US

Assignee:

Abbott Laboratories, Inc. - Abbott Park IL

International Classification:

A01N 43/54
A01N 43/90
C07D 285/00
C07D 285/22

US Classification:

5142581, 5142601, 514267, 544 3, 544 9, 544 10, 544 11, 544 12

Abstract:

The present invention provides an HCV polymerase inhibiting compound having the formula (I).

US Patent:

7910595, Mar 22, 2011

Filed:

Dec 20, 2006

Appl. No.:

11/613810

Inventors:

David A. Betebenner - Libertyville IL, US
David A. DeGoey - Salem WI, US
Clarence J. Maring - Palatine IL, US
Allan C. Krueger - Gurnee IL, US
Nobuhiko Iwasaki - Buffalo Grove IL, US
Todd W. Rockway - Grayslake IL, US
Curt S. Cooper - Vernon Hills IL, US
David D. Anderson - Kenosha WI, US
Pamela L. Donner - Mundelein IL, US
Brian E. Green - Wonder Lake IL, US
Dale J. Kempf - Libertyville IL, US
Dachun Liu - Waukegan IL, US
Keith F. McDaniel - Wauconda IL, US
Darold L. Madigan - Elk Grove Village IL, US
Christopher E. Motter - Oak Creek WI, US
John K. Pratt - Kenosha WI, US
Jason P. Shanley - Chicago IL, US
Michael D. Tufano - Chicago IL, US
Rolf Wagner - Antioch IL, US
Rong Zhang - Niskayuna NY, US
Akhteruzzaman Molla - Gurnee IL, US
Hongmei Mo - Foster City CA, US
Sherie V L. Masse - Kenosha WI, US
Robert J. Carrick - Pleasant Prairie WI, US
Wenping He - Libertyville IL, US
Liangjun Lu - Kildeer IL, US
David J. Grampovnik - Waukegan IL, US

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

C07D 471/04
A01N 31/519
A61P 31/12

US Classification:

51426411, 544279, 5142641

Abstract:

Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.

US Patent:

7915411, Mar 29, 2011

Filed:

Dec 20, 2006

Appl. No.:

11/613825

Inventors:

David A. Betebenner - Libertyville IL, US
David A. DeGoey - Salem WI, US
Clarence J. Maring - Palatine IL, US
Allan C. Krueger - Gurnee IL, US
Nobuhiko Iwasaki - Buffalo Grove IL, US
Todd W. Rockway - Grayslake IL, US
Curt S. Cooper - Vernon Hills IL, US
David D. Anderson - Kenosha WI, US
Pamela L. Donner - Mundelein IL, US
Brian E. Green - Wonder Lake IL, US
Dale J. Kempf - Libertyville IL, US
Dachun Liu - Waukegan IL, US
Keith F. McDaniel - Wauconda IL, US
Darold L. Madigan - Elk Grove Village IL, US
Christopher E. Motter - Oak Creek WI, US
John K. Pratt - Kenosha WI, US
Jason P. Shanley - Chicago IL, US
Michael D. Tufano - Chicago IL, US
Rolf Wagner - Antioch IL, US
Rong Zhang - Niskayuna NY, US
Akhteruzzaman Molla - Gurnee IL, US
Hongmei Mo - Foster City CA, US
Sherie V L. Masse - Kenosha WI, US
Robert J. Carrick - Pleasant Prairie WI, US
Wenping He - Libertyville IL, US
Liangjun Lu - Kildeer IL, US
David J. Grampovnik - Waukegan IL, US

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

C07D 471/04
A61P 1/16

US Classification:

544279

Abstract:

Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.

US Patent:

8232246, Jul 31, 2012

Filed:

Jun 30, 2009

Appl. No.:

12/495299

Inventors:

Keith F. McDaniel - Wauconda IL, US
Dale J. Kempf - Libertyville IL, US

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

A61K 38/00

US Classification:

514 37

Abstract:

Compounds capable of inhibiting replication of the hepatitis C virus (“HCV”) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.