Keith R Walker

US Patent:

6900336, May 31, 2005

Filed:

Jul 16, 2002

Appl. No.:

10/197353

Inventors:

Todd Richard Elworthy - Los Gatos CA, US
Tara Mirzadegan - Los Altos CA, US
Michael Garret Roepel - San Francisco CA, US
David Bernard Smith - San Mateo CA, US
Keith Adrian Walker - Los Altos Hills CA, US

Assignee:

Syntex (U.S.A.) LLC - Palo Alto CA

International Classification:

C07D207/12

US Classification:

548551, 548543

Abstract:

This invention relates to compounds which are generally EPreceptor agonists and which are represented by Formula I: wherein A is a —CH—CH—, or —CH═CH—; B is absent, an aryl, or heteroaryl group; Ris alkyl, alkenyl, alkynyl, cycloalkylalkyl, heterocyclylalkyl, aryl, arylalkyl or heteroaryl, when B is aryl or heteroaryl and R, R, Rand Rare not simultaneously hydrogen, or Ris heterocyclylalkyl, aryl, or heteroaryl when B is absent and R, R, Rand Rare simultaneously hydrogen; and the other substituents are as defined in the specification; or individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds, methods for their use as therapeutic agents, and methods of preparation thereof.

US Patent:

7071177, Jul 4, 2006

Filed:

Apr 26, 2001

Appl. No.:

09/844061

Inventors:

Nancy Elisabeth Krauss - Sunnyvale CA, US
Taraneh Mirzadegan - Los Altos CA, US
David Bernard Smith - San Mateo CA, US
Keith Adrian Walker - Los Altos Hills CA, US

Assignee:

Syntex (U.S.A.) LLC - Palo Alto CA

International Classification:

A01N 51/00
A61K 31/63
C07D 251/00

US Classification:

514155, 514316, 544180, 544194, 544238, 544 92, 544284, 544287, 546152, 546179, 546193, 546201

Abstract:

This invention relates to anti-inflammatory and analgesic compounds, especially to certain p-(sulfonyl)phenyl amino derivatives, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds.

US Patent:

7582760, Sep 1, 2009

Filed:

Jul 12, 2006

Appl. No.:

11/485911

Inventors:

Timothy Owens - Mountain View CA, US
Steven Sethofer - Fremont CA, US
Keith Adrian Walker - Los Altos Hills CA, US
Shu Hai Zhao - Cupertino CA, US

Assignee:

Roche Palo Alto LLC - Palo Alto CA

International Classification:

C07D 403/00
A61K 31/497

US Classification:

544359, 51425212

Abstract:

Compounds of the formula I:.

US Patent:

8326855, Dec 4, 2012

Filed:

Dec 2, 2009

Appl. No.:

12/629555

Inventors:

Ankur Chandra - San Jose CA, US
Nalini K. Kartha - San Jose CA, US
Keith R. Walker - Austin TX, US

Assignee:

International Business Machines Corporation - Armonk NY

International Classification:

G06F 15/16
G06F 3/048

US Classification:

707759, 707802

Abstract:

A system and method for abstracting objects in a virtual universe (VU) deployment is provided. The system and method abstracts VU objects for editing in a common abstraction utility and for deploying to one or more VU grids containing one or more VU architectures and/or platforms (servers). The method can be implemented in a computer infrastructure having programming instructions operable to: obtain an object associated with a first virtual universe server; translate the object with syntax specific to at least a second virtual universe server, the syntax being different than that used with the first virtual universe server; and deploy the translated object to the second virtual universe server.

US Patent:

8495078, Jul 23, 2013

Filed:

Aug 3, 2012

Appl. No.:

13/566591

Inventors:

Ankur Chandra - Bangalore, IN
Nalini K. Kartha - San Jose CA, US
Keith R. Walker - Austin TX, US

Assignee:

International Business Machines Corporation - Armonk NY

International Classification:

G06F 15/16
G06F 3/048

US Classification:

707759, 726 3, 709217, 707802

Abstract:

A system and method for abstracting objects in a virtual universe (VU) deployment is provided. The system and method abstracts VU objects for editing in a common abstraction utility and for deploying to one or more VU grids containing one or more VU architectures and/or platforms (servers). The method can be implemented in a computer infrastructure having programming instructions operable to: obtain an object associated with a first virtual universe server; translate the object with syntax specific to at least a second virtual universe server, the syntax being different than that used with the first virtual universe server; and deploy the translated object to the second virtual universe server.

US Patent:

20020169133, Nov 14, 2002

Filed:

Feb 7, 2002

Appl. No.:

10/072730

Inventors:

Sharon Dankwardt - Sunnyvale CA, US
Harold Van Wart - Los Altos CA, US
Keith Walker - Los Altos CA, US

International Classification:

A61K038/06
C07K005/08

US Classification:

514/018000, 530/331000

Abstract:

This invention relates to compounds of Formula (I) wherein R-R, A, Z and n are as described in the Summary of the Invention that are inhibitors of procollagen C-proteinase, pharmaceutical compositions containing them, methods for their use and methods for their preparation.

US Patent:

20030199520, Oct 23, 2003

Filed:

Oct 9, 2002

Appl. No.:

10/267292

Inventors:

Chris Broka - Foster City CA, US
Jeffrey Campbell - Middletown CT, US
Jian Chen - Santa Clara CA, US
Sharon Dankwardt - Foster City CA, US
Nancy Delaet - San Diego CA, US
Leslie Robinson - San Diego CA, US
Keith Walker - Los Altos CA, US

International Classification:

A61K031/495
A61K031/44
A61K031/381
A61K031/277
C07D213/72
C07D241/04
A61K031/40

US Classification:

514/255030, 514/352000, 514/408000, 514/438000, 514/524000, 544/392000, 546/304000, 548/566000, 558/413000, 558/418000

Abstract:

This invention relates to certain sulfonamide derivatives that are inhibitors of procollagen C-proteinase, pharmaceutical compositions containing them, methods for their use and methods for preparing these compounds.

US Patent:

20030216405, Nov 20, 2003

Filed:

Oct 9, 2002

Appl. No.:

10/267727

Inventors:

Chris Broka - Foster City CA, US
Jeffrey Campbell - Middletown CT, US
Jian Chen - Santa Clara CA, US
Sharon Dankwardt - Foster City CA, US
Nancy Delaet - San Diego CA, US
Leslie Robinson - San Diego CA, US
Keith Walker - Los Altos CA, US

International Classification:

A61K031/496
A61K031/435
A61K031/4184
A61K031/405
A61K031/277
A61K031/165
A61K031/19

US Classification:

514/252130, 514/277000, 514/419000, 514/394000, 514/534000, 514/575000, 544/359000, 546/335000, 546/336000, 548/304400, 548/494000, 560/041000, 562/450000, 562/621000

Abstract:

This invention relates to certain sulfonamide derivatives that are inhibitors of procollagen C-proteinase, pharmaceutical compositions containing them, methods for their use and methods for preparing these compounds.