- Madrid, ES - New York NY, US Paula RIO GALDO - Madrid, ES Susana NAVARRO ORDONEZ - Madrid, ES Elena ALMARZA NOVOA - Madrid, ES Oscar QUINTANA BUSTAMANTE - Madrid, ES Cristina MESA NUNEZ - Madrid, ES Kenneth LAW - New York NY, US Kinnari PATEL - New York NY, US
International Classification:
A61K 35/28 C12N 5/0789 C12N 15/86
Abstract:
The present invention relates generally to methods for genetic modification of hematopoietic cells. In particular, the invention relates to use of Prostaglandin E2 (PGE2), poloxamer, and protamine sulfate to enhance transduction by a recombinant retroviral vector. The compositions and methods of the present disclosure are particularly suitable for gene therapy applications, including the treatment of monogenic genetic diseases and disorders.
Isbn (Books And Publications)
Translating Questionnaires and Other Research Instruments: Problems and Solutions
Sep 24, 2009 ... Kenneth Law is Associate Professor of violoncello at the Carroll McDaniel Petrie School of Music of Converse College, a liberal arts ...