Kenneth Fitzgerald Powell

US Patent:

6589202, Jul 8, 2003

Filed:

Jun 29, 2000

Appl. No.:

09/606907

Inventors:

Kenneth G. Powell - Raleigh NC

Assignee:

Becton Dickinson and Company - Franklin Lakes NY

International Classification:

A61M 100

US Classification:

604 27, 6048901

Abstract:

A device for delivering or withdrawing a substance from a patient includes a support member, a skin penetrating device and an advancing assembly for advancing the skin penetrating device to an operating position. The advancing assembly includes a supply spool for supporting a web having the skin penetrating devices attached thereon and a take up spool for receiving the web with the spent skin penetrating devices. The support has a bottom wall with at least one opening for exposing the skin penetrating device for penetrating the skin of a patient. In one embodiment the skin penetrating devices are micro needles having a length of about 50-2000 microns.

US Patent:

6589229, Jul 8, 2003

Filed:

Jul 31, 2000

Appl. No.:

09/629977

Inventors:

Robert I. Connelly - Raleigh NC
Charles D. Shermer - Raleigh NC
Kenneth G. Powell - Raleigh NC

Assignee:

Becton, Dickinson and Company

International Classification:

A61K 922

US Classification:

6048901, 604 65, 604 66, 604 67

Abstract:

A wearable, self contained drug infusion device is disclosed that is capable of achieving the precise flow rate control needed for dose-critical drugs such as insulin. In preferred embodiments of the device, piezoelectrically-actuated valve or pump structures are used in combination with thermal flow sensors and closed-loop control circuits for providing the desired flow rate control. The device has a two-part construction in which the more expensive electronic components are housed in a reusable portion and the fluid delivery components are housed in a separable disposable portion. The invention may also utilize a wireless unit for controlling the operation of the drug infusion device.

US Patent:

6702779, Mar 9, 2004

Filed:

Aug 17, 2001

Appl. No.:

09/931102

Inventors:

Robert I. Connelly - Raleigh NC
Kenneth G. Powell - Raleigh NC

Assignee:

Becton, Dickinson and Company - Franklin Lakes NJ

International Classification:

A61M 3100

US Classification:

604 9301, 6048901

Abstract:

A wearable, self-contained drug infusion device is disclosed that is capable of achieving the precise flow rate control needed for dose-critical drugs such as insulin. In preferred embodiments of the device, at least two flow channels are utilized in conjunction with a series of valves for providing a user with selectable, constant flow rate control. The device can be made with small dimensions so that it can be worn by the user with a minimum of discomfort and inconvenience. In addition, the simple mechanical nature of the device provides the user with close control over the flow rate, which is required for safe and effective delivery of insulin and other drugs. Also, the absence of electronic components allows the device to be manufactured inexpensively. The device is provided with a first channel that is long and narrow, functioning as a flow restrictor. The first channel is preferably provided in a serpentine pattern.

US Patent:

7024836, Apr 11, 2006

Filed:

Oct 7, 2003

Appl. No.:

10/679271

Inventors:

Kenneth G. Powell - Raleigh NC, US
Carl Sahi - Coventry CT, US
Charles Shermer - Raleigh NC, US
John Polidoro - Coventry CT, US
Chad C. Smutney - Stafford Springs CT, US

Assignee:

Becton, Dickinson and Company - Franklin Lakes NJ

International Classification:

B65B 3/04
B65B 31/02

US Classification:

53469, 53434, 53 86

Abstract:

Methods for filling and sealing containers having one or more flexible sides. Non-standard containers for holding fluid are releasably supported during the filling and sealing process. Both the interior and exterior of the filled container are subjected to an environment of reduced pressure to minimize the headspace and sealed.

US Patent:

7052268, May 30, 2006

Filed:

Jul 24, 2003

Appl. No.:

10/626391

Inventors:

Kenneth G. Powell - Raleigh NC, US
Larry A. Monahan - Raleigh NC, US

Assignee:

Becton, Dickinson and Company - Franklin Lakes NJ

International Classification:

B29C 33/38

US Classification:

425542, 425470, 249134

Abstract:

A device, preferably a micro-device, is molded from a plastic material by injection molding, compression molding or embossing. A microabrader can be molded having microneedles for abrading the stratum corneum of the skin to form an abraded site in the tissue for enhancing drug delivery. The micro-device is molded using a mold assembly having a silicon molding surface. The silicon molding surface can include a recess corresponding to the desired shape and length of the microneedles. The silicon molding surface enables micron and submicron size features to be molded from polymeric materials without the polymeric material adhering to the mold surface. Micro-devices having molded features having micron and submicron dimensions can be rapidly produced without the use of a release agent.

US Patent:

7150138, Dec 19, 2006

Filed:

Feb 22, 2006

Appl. No.:

11/359351

Inventors:

Kenneth G. Powell - Raleigh NC, US
Carl Sahi - Coventry CT, US
Charles Shermer - Raleigh NC, US
John Polidoro - Coventry CT, US
Chad C. Smutney - Stafford Springs CT, US

Assignee:

Becton, Dickinson and Company - Franklin Lakes NJ

International Classification:

B65B 3/04
B65B 31/02

US Classification:

53469, 53434, 53 86

Abstract:

Methods for filling and sealing containers having one or more flexible sides. Non-standard containers for holding fluid are releasably supported during the filling and sealing process. Both the interior and exterior of the filled container are subjected to an environment of reduced pressure to minimize the headspace and sealed.

US Patent:

7214221, May 8, 2007

Filed:

Mar 26, 2003

Appl. No.:

10/396719

Inventors:

James K. Fentress - Morrisville NC, US
Kenneth G. Powell - Raleigh NC, US

Assignee:

Becton, Dickinson and Company - Franklin Lakes NJ

International Classification:

A61K 9/22

US Classification:

6048901, 6048911, 604134

Abstract:

A fluid delivery device for delivering a substance to a patient by way of infusion delivers the preparation at a rate of flow which varies in steps from a substantially constant higher rate, to a stepped-down substantially constant lower rate or rates. The delivery device includes one or more reservoirs, and one or more Belleville springs for applying generally constant pressures to the substance contained in the reservoirs. Each reservoir will have a different constant pressure applied in a mid-range of operation. The reservoirs can be interconnected to each other and to an infusion device in a number of arrangements, including various manifolds and flow restrictors, such that the rate of flow is controlled in steps in accordance with the pressures applied by the springs of the plurality of reservoirs.

US Patent:

7250037, Jul 31, 2007

Filed:

Jul 22, 2003

Appl. No.:

10/623702

Inventors:

Charles D. Shermer - Raleigh NC, US
Kenneth G. Powell - Raleigh NC, US
Alexander G. Lastovich - Raleigh NC, US
P. Spencer Kinsey - Vernon CT, US
Chad C. Smutney - Stafford Springs CT, US
John M. Polidoro - Coventry CT, US
Ed Browka - Oakland NJ, US
Carl R. Sahi - Coventry CT, US
James K. Fentress - Morrisville NC, US
David S. Chapin - Raleigh NC, US
Daniel Stipe - Raleigh NC, US
Jeff M. Moss - Golden CO, US
Melody Kuroda - Oakland NJ, US

Assignee:

Becton, Dickinson and Company - Franklin Lakes NJ

International Classification:

A61M 5/20

US Classification:

604134

Abstract:

A system and method for a patch-like, self-contained substance infusion device which provides one or more substantially hidden patient needles which can be placed in fluid communication with a fluid reservoir subassembly that includes a rigid bladder portion used in conjunction with a non-distensible bladder film, such as a metallized film. Simple removal of an interlock allows a disk, or Belleville spring assembly to apply an essentially even and constant pressure to the contents of the fluid reservoir assembly, and allows the device to then be attached to a skin surface via an adhesive contact surface. A push button activation assembly is provided which can then be used to release and seat one or more spring-loaded patient needles into the skin surface, and establish a fluid communication path between the patient needles and the pressurized fluid reservoir contents thereby delivering an infusion into the skin.