Kevin K Chen

US Patent:

6624945, Sep 23, 2003

Filed:

Feb 12, 2001

Appl. No.:

09/781825

Inventors:

Shanhui Fan - Palo Alto CA
John D. Joannopoulos - Belmont MA
George B. Kenney - Medfield MA
Michal Lipson - Waltham MA
Kevin M. Chen - Cambridge MA
Lionel C Kimerling - Concord MA

Assignee:

Massachusetts Institute of Technology - Cambridge MA

International Classification:

G02B 2700

US Classification:

359584, 359587, 359580, 359578, 359577

Abstract:

An electromagnetic wavelength filter that allows the transmission of electromagnetic energy within a narrow range of wavelengths while reflecting incident electromagnetic energy at other wavelengths. The filter includes at least one cavity region; and at least two reflectors surrounding the at least one cavity region, at least one of the reflectors being an omni-directional reflector. The omni-directional reflector includes a structure with a surface and an index of refraction variation perpendicular to the surface, and the omni-directional reflector is specifically configured to exhibit high omni-directional reflection for a predetermined range of frequencies of incident electromagnetic energy for any angle of incidence and any polarization.

US Patent:

6846509, Jan 25, 2005

Filed:

Nov 21, 2001

Appl. No.:

09/991438

Inventors:

Kevin M. Chen - Santa Clara CA, US
Lionel C. Kimerling - Concord MA, US

Assignee:

Massachusetts Institute of Technology - Cambridge MA

International Classification:

B05D 302
B05D 512
C23C 1400

US Classification:

427 66, 427 74, 4271263, 427166, 427380, 20419215, 20419226

Abstract:

A system for producing Erbium Oxide thin films with increased photoluminescence. The system includes a depositing stage for forming Erbium Oxide molecules by reacting Erbium sputtered atoms with Oin a gas phase and creating the Erbium Oxide thin film by depositing the Erbium Oxide molecules on a substrate coated with Silicon Oxide. The system further includes an annealing stage for annealing the Erbium Oxide thin films by utilizing a low temperature treatment for a specified amount of time and temperature followed by a high temperature treatment for another specified amount of time and temperature, wherein the crystallinity of the thin films has improved.

US Patent:

6914122, Jul 5, 2005

Filed:

Apr 17, 2001

Appl. No.:

09/836636

Inventors:

Srikanth Venkatraman - Woodbridge NJ, US
Kevin X. Chen - Iselin NJ, US
Ashok Arasappan - Bridgewater NJ, US
F. George Njoroge - Warren NJ, US
Viyyoor Moopil Girijavallabhan - Parsippany NJ, US
Ashit K. Ganguly - Upper Montclair NJ, US
Tin-Yau Chan - Edison NJ, US
Brian Alexander Mc Kittrick - Bloomfield NJ, US
Nanhua Hugh Yao - Irvine CA, US
Andrew Joseph Prongay - Stewartsville NJ, US
Vincent Stewart Madison - Mountain Lakes NJ, US

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

C07K007/50

US Classification:

530317, 514 11

Abstract:

The present invention discloses novel macrocyclic compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such macrocycles as well as methods of using them to treat disorders associated with the HCV protease.

US Patent:

7012066, Mar 14, 2006

Filed:

Jul 19, 2001

Appl. No.:

09/908955

Inventors:

Anil K. Saksena - Upper Montclair NJ, US
Viyyoor Moopil Girijavallabhan - Parsippany NJ, US
Raymond G. Lovey - West Caldwell NJ, US
Edwin Jao - Warren NJ, US
Frank Bennett - Piscataway NJ, US
Jinping L. Mc Cormick - Edison NJ, US
Haiyan Wang - Cranbury NJ, US
Russell E. Pike - Stanhope NJ, US
Stephane L. Bogen - Somerset NJ, US
Tin-Yau Chan - Edison NJ, US
Yi-Tsung Liu - Morris Township NJ, US
Zhaoning Zhu - East Windsor NJ, US
F. George Njoroge - Warren NJ, US
Ashok Arasappan - Bridgewater NJ, US
Tejal Parekh - Mountain View CA, US
Ashit K. Ganguly - Upper Montclair NJ, US
Kevin X. Chen - Iselin NJ, US
Srikanth Venkatraman - Fords NJ, US
Henry A. Vaccaro - South Plainfield NJ, US
Patrick A. Pinto - Morris Plains NJ, US
Bama Santhanam - Bridgewater NJ, US
Scott Jeffrey Kemp - San Diego CA, US
Odile Esther Levy - San Diego CA, US
Marguerita Lim-Wilby - La Jolla CA, US
Susan Y. Tamura - Santa Fe NM, US
Wanli Wu - Edison NJ, US
Siska Hendrata - Edison NJ, US
Yuhua Huang - Scotch Plains NJ, US

Assignee:

Schering Corporation - Kenilworth NJ
Dendreon Corporation - Seattle WA

International Classification:

A61K 38/07
A61K 38/06
C07K 5/08
C07K 5/10

US Classification:

514 18, 530330, 530331

Abstract:

The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.

US Patent:

7169760, Jan 30, 2007

Filed:

Jul 19, 2001

Appl. No.:

09/909012

Inventors:

Anil K. Saksena - Upper Montclair NJ, US
Viyyoor Moopil Girijavallabhan - Parsippany NJ, US
Stephane L. Bogen - Somerset NJ, US
Raymond G. Lovey - West Caldwell NJ, US
Edwin Jao - Warren NJ, US
Frank Bennett - Piscataway NJ, US
Jinping L. Mc Cormick - Edison NJ, US
Haiyan Wang - Cranbury NJ, US
Russell E. Pike - Stanhope NJ, US
Yi-Tsung Liu - Morris Township NJ, US
Tin-Yau Chan - Edison NJ, US
Zhaoning Zhu - East Windsor NJ, US
Ashok Arasappan - Bridgewater NJ, US
Kevin X. Chen - Iselin NJ, US
Srinkanth Venkatraman - Fords NJ, US
Tejal Parekh - Mountain View CA, US
Patrick A. Pinto - Morris Plains NJ, US
Bama Santhanam - Bridgewater NJ, US
F. George Njoroge - Warren NJ, US
Ashit K. Ganguly - Upper Montclair NJ, US
Henry A. Vaccaro - South Plainfield NJ, US
Scott Jeffrey Kemp - San Diego CA, US
Odile Esther Levy - San Diego CA, US
Marguerita Lim-Wilby - La Jolla CA, US
Susan Y. Tamura - Santa Fe NM, US

Assignee:

Schering Corporation - Kenilworth NJ
Dendreon Corporation - Seattle WA

International Classification:

A61K 38/05
A61K 31/44
A61K 31/16
A61K 31/227

US Classification:

514 19, 514616, 564154, 564152, 564155

Abstract:

The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.

US Patent:

7173057, Feb 6, 2007

Filed:

Feb 24, 2005

Appl. No.:

11/065647

Inventors:

Kevin X. Chen - Edison NJ, US
F. George Njoroge - Warren NJ, US
Mousumi Sannigrahi - Summit NJ, US
Latha G. Nair - Edison NJ, US
Weiying Yang - Edison NJ, US
Bancha Vibulbhan - Kenilworth NJ, US
Srikanth Venkatraman - Woodbridge NJ, US
Ashok Arasappan - Bridgewater NJ, US
Stephane L. Bogen - Somerset NJ, US
Frank Bennett - Cranford NJ, US
Viyyoor M. Girijavallabhan - Parsippany NJ, US

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

A61K 31/4035
A61K 31/403
A61K 31/407
A61K 31/454
A61K 31/5355
A61K 31/4725
A61K 31/4166
C07D 209/48
C07D 209/52
C07D 209/02
C07D 471/02
C07D 401/12
C07D 413/12
C07D 217/24
C07D 233/02
C07D 233/74

US Classification:

514414, 514300, 514387, 514323, 5142308, 514309, 514389, 5483195, 548465, 548455, 546113, 546201, 546142, 544143

Abstract:

The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.

US Patent:

7192957, Mar 20, 2007

Filed:

Feb 24, 2005

Appl. No.:

11/065509

Inventors:

Srikanth Venkatraman - Woodbridge NJ, US
F. George Njoroge - Warren NJ, US
Melissa L. Blackman - Ocean NJ, US
Wanli Wu - Edison NJ, US
Latha G. Nair - Edison NJ, US
Ashok Arasappan - Bridgewater NJ, US
Stephane L. Bogen - Somerset NJ, US
Kevin X. Chen - Edison NJ, US
Mousumi Sannigrahi - Summit NJ, US
Frank Bennett - Cranford NJ, US
Viyyoor M. Girijavallabhan - Parsippany NJ, US

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

A61K 31/4035
A61K 31/454
A61K 31/5377
A61K 31/4439
A61K 31/4402
C07D 413/12
C07D 401/12
C07D 209/54

US Classification:

5142308, 514323, 514339, 514412, 514414, 544143, 546201, 5462771, 548515, 548465

Abstract:

The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.

US Patent:

7244721, Jul 17, 2007

Filed:

Jan 18, 2002

Appl. No.:

10/052386

Inventors:

Anil K. Saksena - Upper Montclair NJ, US
Viyyoor Moopil Girijavallabhan - Parsippany NJ, US
Raymond G. Lovey - West Caldwell NJ, US
Edwin Jao - Warren NJ, US
Frank Bennett - Piscataway NJ, US
Jinping L. Mc Cormick - Edison NJ, US
Haiyan Wang - Cranbury NJ, US
Russell E. Pike - Stanhope NJ, US
Stephane L. Bogen - Somerset NJ, US
Tin-Yau Chan - Edison NJ, US
Yi-Tsung Liu - Morris Township NJ, US
Zhaoning Zhu - East Windsor NJ, US
F. George Njoroge - Warren NJ, US
Ashok Arasappan - Bridgewater NJ, US
Tejal Parekh - Mountain View CA, US
Ashit K. Ganguly - Upper Montclair NJ, US
Kevin X. Chen - Iselin NJ, US
Srikanth Venkatraman - Woodbridge NJ, US
Henry A. Vaccaro - South Plainfield NJ, US
Patrick A. Pinto - Morris Plains NJ, US
Bama Santhanam - Bridgewater NJ, US
Scott Jeffrey Kemp - San Diego CA, US
Odile Esther Levy - San Diego CA, US
Marguerita Lim-Wilby - La Jolla CA, US
Susan Y. Tamura - San Diego CA, US
Wanli Wu - Edison NJ, US
Siska Hendrata - Rockaway NJ, US
Yuhua Huang - Scotch Plains NJ, US
Jesse K. Wong - Monroe Township NJ, US
Latha G. Nair - Scotch Plains NJ, US

Assignee:

Schering Corporation - Kenilworth NJ
Dendreon Corporation - Seattle WA

International Classification:

A61K 31/497
A61K 31/407
A61K 31/454
A61K 31/4025

US Classification:

51421021, 530330, 530331

Abstract:

The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.