Kevin Y Chen

US Patent:

7190853, Mar 13, 2007

Filed:

Jun 25, 2002

Appl. No.:

10/178965

Inventors:

John D. Joannopoulos - Belmont MA, US
Shanhui Fan - Somerville MA, US
Michal Lispon - Waltham MA, US
Kevin M. Chen - Santa Clara CA, US
Lionel C. Kimerling - Concord MA, US

Assignee:

Massachusetts Institute of Technology - Cambridge MA

International Classification:

G02B 6/26

US Classification:

385 15, 385129, 385130

Abstract:

A system for dispersion compensation is provided including a plurality of optical cavities with each including a specific resonant frequency and resonant linewidth. At least one coupling element interconnects the optical cavities. The at least one coupling element defines the coupling strength between the cavities. The optical cavities are interconnected with the at least one coupled element that forms a multi-cavity structure. The multi-cavity structure generates appropriate dispersion properties for dispersion compensation purposes.

US Patent:

20130156731, Jun 20, 2013

Filed:

Dec 20, 2010

Appl. No.:

13/518336

Inventors:

Kevin X. Chen - Cambridge MA, US
Stuart B. Rosenblum - Malden MA, US
Joseph A. Kozlowski - Princeton NJ, US
F. George Njoroge - Camel IN, US

International Classification:

A61K 45/06
A61K 31/454
C07D 403/14
C07D 409/14
A61K 31/4184

US Classification:

424 854, 5483021, 514394, 546199, 514322, 4241411, 4241301, 514 44 A, 4241841

Abstract:

The present invention relates to novel Fused Tricyclic Compounds, compositions comprising at least one Fused Tricyclic Compound, and methods of using Fused Tricyclic Compounds for treating or preventing a viral infection or a virus-related disorder in a patient.

US Patent:

20190338238, Nov 7, 2019

Filed:

May 3, 2019

Appl. No.:

16/403161

Inventors:

- Cambridge MA, US
Jason Walther - Holliston MA, US
Jonathan Wang - Brighton MA, US
Kevin Victor Chen - Marlborough MA, US

International Classification:

C12M 1/36
B01D 61/18
B01D 61/22
B01D 15/18
C12M 1/00
C12M 1/34

Abstract:

The disclosure provides a filtration system for a cell culture apparatus and a method of cell culture. The filtration system comprises a bioreactor vessel and two or more alternating tangential flow (ATF) filters connected in parallel. A failure in either filter is detected by an in-line sensor, and an automated response system functions to sequester the malfunctioning filter by stopping the flow of liquid media through the filter. Media flow through the remaining operable filters can be increased so that the rate of perfusion through the bioreactor remains relatively unchanged. Such a system may prevent issues that arise from ATF filter failures in conventional perfusion bioreactors, thereby improving the long-term viability of cell cultures.