The Regents of the University of California - Oakland CA, US Tao Zhang - San Diego CA, US Kanwar K. Singh - Pittsburg CA, US Len A. Pennacchio - Sebastopol CA, US Jeff L. Froula - Walnut Creek CA, US Kevin S. Eng - San Francisco CA, US
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA
International Classification:
C12Q 1/68
US Classification:
506 2
Abstract:
Methods for sequencing single large DNA molecules by clonal multiple displacement amplification using barcoded primers. Sequences are binned based on barcode sequences and sequenced using a microdroplet-based method for sequencing large polynucleotide templates to enable assembly of haplotype-resolved complex genomes and metagenomes.
Diagnostic Markers For Treating Cell Proliferative Disorders With Telomerase Inhibitors
- Menlo Park CA, US Bart BURINGTON - Oakland CA, US Hui WANG - Sunnyvale CA, US Kevin ENG - Mountain View CA, US
International Classification:
C12Q 1/68
Abstract:
Provided herein are methods for identifying individuals diagnosed with a cell proliferative disorder that will benefit from treatment with a telomerase inhibitor compound. Also provided herein are methods for treating these individuals with telomerase inhibitor compounds.
Diagnostic Markers For Treating Cell Proliferative Disorders With Telomerase Inhibitors
- Menlo Park CA, US Bart BURINGTON - Oakland CA, US Hui WANG - Sunnyvale CA, US Kevin ENG - Mountain View CA, US
International Classification:
C12Q 1/68 C12N 15/113
Abstract:
Provided herein are methods for identifying individuals diagnosed with a cell proliferative disorder that will benefit from treatment with a telomerase inhibitor compound. Also provided herein are methods for treating these individuals with telomerase inhibitor compounds. The methods comprise identifying individuals who will benefit from said treatment based on the average relative length of telomeres in cancer cells from said individuals.
Diagnostic Markers For Treating Cell Proliferative Disorders With Telomerase Inhibitors
- Menlo Park CA, US Bart Burington - Oakland CA, US Hui Wang - Sunnyvale CA, US Kevin Eng - Mountain View CA, US
International Classification:
C12Q 1/68
US Classification:
514 44 R, 435 612, 435 611
Abstract:
Provided herein are methods for identifying individuals diagnosed with a cell proliferative disorder that will benefit from treatment with a telomerase inhibitor compound. Also provided herein are methods for treating these individuals with telomerase inhibitor compounds.
Resumes
Associate Director Alliance Management And Business Development
Geron - Menlo Park, CA since Sep 2012
Scientist, Business Development
Geron - Menlo Park, CA since Aug 2012
Scientist, Translational Research
Geron Corporation Aug 2010 - Aug 2012
Postdoctoral Scientist
Natera - San Carlos, CA Dec 2011 - Mar 2012
Consultant, Research
Education:
Case Western Reserve University School of Medicine 2005 - 2010
PhD, Pharmacology
University of California, Irvine 2000 - 2004
BS, Biological Sciences
Skills:
Pharmacology Assay Development Genomics Protein Chemistry Biochemistry Protein Purification Biotechnology Clinical Development Biomarkers Biomarker Discovery High Throughput Screening Translational Research
Olofson Environmental, Inc.
Field Biologist
Copper Mountain Resort Nov 2012 - May 2014
Certified Ski Instructor
Nyc Department of Parks & Recreation Dec 2013 - Feb 2014
Project Specialist and Field Biologist
Mountain Creek Ski Resort Oct 2007 - Feb 2014
Ski and Snowboard Instructor
Natural Areas Conservancy May 2013 - Nov 2013
Field Biologist
Education:
Rutgers University 2007 - 2012
Bachelors, Bachelor of Arts, Biology
Randolph High School 2003 - 2007
Randolph High School, Nj 2007
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City and County of San Francisco
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City and County of San Francisco Jan 1, 2016 - Feb 2017
Environmental Health Inspector
Kern County Environmental Health Services Sep 2013 - Jan 2016
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San Francisco Department of Public Health Jul 2012 - Jul 2013
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San Francisco Department of Elections Oct 2012 - Nov 2012
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Uc Irvine 2008 - Jun 2012
Bachelors, Bachelor of Science, Public Health
Galileo High School
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Pacific Biosciences since Nov 2012
Senior Research Associate
Education:
University of Michigan - Flint 1995 - 1998
Bachelors, Bachelor of Science, Health Science, Physical Therapy
University of California, Santa Cruz 1986 - 1990
Bachelors, Bachelor of Arts, Biology
Skills:
Molecular Biology Biotechnology Pcr Qpcr Lifesciences Western Blotting Cell Culture Drug Discovery Sequencing Rt Pcr Genomics Life Sciences Polymerase Chain Reaction Transfection Rna Isolation Genetics
"Ovarian cancer is sometimes called the silent killer. It's hard to detect, and it's hard to predict," said Kevin Eng, an associate professor of oncology at the Roswell Park Comprehensive Cancer Center and a leading author of the study.
Date: Feb 24, 2018
Category: Health
Source: Google
Fathers' Genes Could Raise Daughters' Ovarian Cancer Risk
think that other cases of ovarian cancermight actually be inherited from one's father, via the X chromosome. Lead study author Kevin Eng and his team at the Roswell Park Center Institute in Buffalo, New York, narrowed things down to one suspect gene - MAGEC3 - on the X chromosome from the father.
"Our study may explain why we find families with multiple affected daughters: Because a dad's chromosomes determine the sex of his children, all of his daughters have to carry the same X chromosome genes," said study author Kevin Eng. He's an assistant professor of oncology at Roswell Park Comprehen
Date: Feb 16, 2018
Category: Health
Source: Google
Ovarian Cancer Risk Factors May Include Your Father's Genes
Women carry two X chromosomes in their cellsone from their mother, the other from their father. The gene does exist on moms chromosomes, too, Kevin Eng, a researcher at the Roswell Park Cancer Institute who was one of the authors of the paper, told Newsweek. But because a womans father has only
Date: Feb 16, 2018
Category: Health
Source: Google
Fathers May Pass On Increased Risk For Ovarian Cancer To Daughters
Kevin Eng and colleagues focused on the gene MAGEC3, found in the X chromosome inherited from fathers. Ovarian cancers linked to genes from the father had an earlier onset than genes liked to the maternal side.
Lead author Kevin Eng from the Roswell Park Comprehensive Cancer Centre in Buffalo, New York said: "What we have to do next is make sure we have the right gene by sequencing more families. This finding has sparked a lot of discussion within our group about how to find these X-linked families.
Date: Feb 15, 2018
Category: Health
Source: Google
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Center Grove Elementary School Randolph NJ 1996-2000
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