Kevin Antonio Hester

US Patent:

8182993, May 22, 2012

Filed:

Jun 5, 2008

Appl. No.:

12/134186

Inventors:

Austin B. Tomaney - San Francisco CA, US
Kenneth Mark Maxham - Redwood City CA, US
David Holden - Burlingame CA, US
Kevin Hester - Belmont CA, US
Devon Murphy - Mountain View CA, US
Patrick Marks - San Francisco CA, US

Assignee:

Pacific Biosciences of California, Inc. - Menlo Park CA

International Classification:

C12Q 1/68
C12P 19/34
C07H 21/04

US Classification:

435 612, 435 912, 536 2433

Abstract:

Computer implemented methods, and systems performing such methods for processing signal data from analytical operations and systems, and particularly in processing signal data from sequence-by-incorporation processes to identify nucleotide sequences of template nucleic acids and larger nucleic acid molecules, e. g. , genomes or fragments thereof.

US Patent:

8318094, Nov 27, 2012

Filed:

Jun 16, 2011

Appl. No.:

13/162433

Inventors:

Hovig Bayandorian - Berkeley CA, US
Yujuan Cheng - Foster City CA, US
John Dixon - Moss Beach CA, US
Kevin Hester - Belmont CA, US
Yanqiao Huang - San Mateo CA, US
Paul Lundquist - San Francisco CA, US
Joy Roy - San Jose CA, US
Stephen Turner - Menlo Park CA, US
Peiqian Zhao - Mountain View CA, US
Cheng Frank Zhong - Fremont CA, US

Assignee:

Pacific Biosciences of California, Inc. - Menlo Park CA

International Classification:

G01N 31/00

US Classification:

422 63, 422 62, 422 67, 422 681, 422 8205, 422400, 436 43, 436164

Abstract:

This invention provides systems for analyzing substrates. Also provided by the invention are improved optical systems for enhanced multiplex illumination, optical systems with compact multi-wavelength illumination architectures, optical systems for enhanced detection of optical signals, and optical systems for reduced autofluorescence background noise.

US Patent:

20110256631, Oct 20, 2011

Filed:

Feb 24, 2011

Appl. No.:

13/034199

Inventors:

Austin Tomaney - Burlingame CA, US
Kenneth Mark Maxham - Redwood City CA, US
David Holden - Burlingame CA, US
Kevin Hester - Belmont CA, US
Devon Murphy - Mountain View CA, US
Patrick Marks - San Francisco CA, US

Assignee:

Pacific Biosciences of California, Inc. - Menlo Park CA

International Classification:

G01N 33/50
G06F 15/18

US Classification:

436 94, 706 12

Abstract:

Computer implemented methods, and systems performing such methods for processing signal data from analytical operations and systems, and particularly in processing signal data from sequence-by-incorporation processes to identify nucleotide sequences of template nucleic acids and larger nucleic acid molecules, e.g., genomes or fragments thereof.

US Patent:

20160097093, Apr 7, 2016

Filed:

Oct 13, 2015

Appl. No.:

14/882110

Inventors:

- Menlo Park CA, US
Kenneth Mark Maxham - Redwood City CA, US
David Holden - Burlingame CA, US
Kevin Hester - Belmont CA, US
Devon Murphy - Mountain View CA, US
Patrick Marks - San Francisco CA, US

International Classification:

C12Q 1/68
G01N 21/64

Abstract:

Computer implemented methods, and systems performing such methods for processing signal data from analytical operations and systems, and particularly in processing signal data from sequence-by-incorporation processes to identify nucleotide sequences of template nucleic acids and larger nucleic acid molecules, e.g., genomes or fragments thereof

US Patent:

20160017024, Jan 21, 2016

Filed:

Mar 7, 2014

Appl. No.:

14/773329

Inventors:

- South San Francisco CA, US
Hongbing Zhang - Albany CA, US
Kevin Hester - Kensington CA, US
Thomas Harding - South San Francisco CA, US

International Classification:

C07K 16/18
C07K 16/40
G01N 33/573
A61K 45/06
A61K 39/395
A61K 38/17
C07K 16/00
A61K 38/45

Abstract:

Methods of identifying and using FAM150A agents, FAM150B agents, and FAM150 antagonists are provided. Methods of identifying and using LTK agonists (including LTK agonist antibodies, FAM150A agents, and FAM150B agents) and FAM150 antagonists are provided. Such methods include, but are not limited to, methods of treating cancer, methods of treating immune disorders such as autoimmune diseases, and methods of treating neurodegenerative diseases.