Kevin E Kearney

US Patent:

7298415, Nov 20, 2007

Filed:

May 11, 2005

Appl. No.:

11/127842

Inventors:

David Nilson - Walnut Creek CA, US
Michael D. Cable - Danville CA, US
Bradley W. Rice - Danville CA, US
Kevin Kearney - Fairport NY, US

Assignee:

Xenogen Corporation - Alameda CA

International Classification:

H04N 5/222
A61B 6/00

US Classification:

348370, 600476

Abstract:

The present invention integrates a structured light source into an imaging system for reconstructing surface topography of an object being imaged. The structured light source includes a mechanism for transmitting a set of lines onto the object from an angle. The lines are displaced, or phase shifted relative to a stage, when they encounter an object with finite height, such as a mouse. This phase shift provides structured light information for the object. A camera captures the structured light information. Using software that employs a structured light analysis, surface topography data for the object is determined from the phase shift of the lines.

US Patent:

7797034, Sep 14, 2010

Filed:

May 11, 2005

Appl. No.:

11/127346

Inventors:

Bradley W. Rice - Danville CA, US
Michael D. Cable - Danville CA, US
Kevin Kearney - Fairport NY, US

Assignee:

Xenogen Corporation - Alameda CA

International Classification:

A61B 6/03
A61B 6/12

US Classification:

600473, 600425, 600476, 25036301, 2503171, 382128

Abstract:

The present invention provides systems and methods for obtaining a three-dimensional (3D) representation of one or more light sources inside a sample, such as a mammal. Mammalian tissue is a turbid medium, meaning that photons are both absorbed and scattered as they propagate through tissue. In the case where scattering is large compared with absorption, such as red to near-infrared light passing through tissue, the transport of light within the sample is described by diffusion theory. Using imaging data and computer-implemented photon diffusion models, embodiments of the present invention produce a 3D representation of the light sources inside a sample, such as a 3D location, size, and brightness of such light sources.

US Patent:

8279334, Oct 2, 2012

Filed:

Oct 11, 2007

Appl. No.:

11/871062

Inventors:

David Nilson - Walnut Creek CA, US
Michael D. Cable - Danville CA, US
Bradley W. Rice - Danville CA, US
Kevin Kearney - Fairport NY, US

Assignee:

Xenogen Corporation - Alameda CA

International Classification:

H04N 5/225
A61B 6/00

US Classification:

348374, 600476

Abstract:

The present invention integrates a structured light source into an imaging system for reconstructing surface topography of an object being imaged. The structured light source includes a mechanism for transmitting a set of lines onto the object from an angle. The lines are displaced, or phase shifted relative to a stage, when they encounter an object with finite height, such as a mouse. This phase shift provides structured light information for the object. A camera captures the structured light information. Using software that employs a structured light analysis, surface topography data for the object is determined from the phase shift of the lines.