Kevin Joseph Mccarthy

US Patent:

D497092, Oct 12, 2004

Filed:

Aug 26, 2002

Appl. No.:

29/166324

Inventors:

Kevin J. McCarthy - Woodbury MN

Assignee:

3M Innovative Properties Company - St. Paul MN

International Classification:

0805

US Classification:

D 8 90, D32 40

US Patent:

7621802, Nov 24, 2009

Filed:

Aug 26, 2002

Appl. No.:

10/227713

Inventors:

Kevin J. McCarthy - Woodbury MN, US

Assignee:

3M Innovative Properties Company - St. Paul MN

International Classification:

B24D 11/00

US Classification:

451523, 451533

Abstract:

A hand held corner sanding sponge includes a backing layer of an open-celled foam material having first and second major surfaces that meet at a right angle and third and fourth major surfaces that meet at a right angle. The cross-sectional dimension between the intersection of the first and second major surfaces from the intersection of the third and fourth major surfaces is about 4 inches to about 6 inches. First and second side surfaces are located between the first and second major surface and the third and fourth major surfaces forming a generally hexagonal shape. The cross-sectional dimension between the first and second side surfaces is about 3 inches to about 4 inches. A layer of flexible adhesive is adhered to at least the first and second major surfaces of the backing layer. A layer of abrasive particles is adhered to the major surfaces by the flexible adhesive.

US Patent:

20080070268, Mar 20, 2008

Filed:

Apr 21, 2007

Appl. No.:

11/788872

Inventors:

Karin Anderson - Georgetown MA, US
Niall Barron - Shankill, IE
Timothy Charlebois - Andover MA, US
Martin Clynes - Clontarf, IE
Dana Di Nino - North Andover MA, US
Padraig Doolan - Swords, IE
Patrick Gammell - Naas, IE
Kathleen Kopycinski - Somerville MA, US
Mark Leonard - Manchester NH, US
Kevin McCarthy - North Andover MA, US
Paula Meleady - Ratoath, IE
Mark Melville - Melrose MA, US
Martin Sinacore - Andover MA, US

Assignee:

Wyeth - Madison NJ
Dublin City University - Dublin

International Classification:

C07H 21/04
C07K 16/00
C12N 5/04
C12Q 1/20

US Classification:

435029000, 435325000, 435375000, 530350000, 536022100

Abstract:

The present invention provides methods for systematically identifying genes and proteins and related pathways that maximize protein expression and secretion by expression profiling analysis. The present invention further provides methods for manipulating the identified genes and proteins to engineer improved cell lines.

US Patent:

20090017460, Jan 15, 2009

Filed:

Jun 13, 2008

Appl. No.:

12/139294

Inventors:

Karin Anderson - Georgetown MA, US
Niall Barron - Shankill, IE
Martin Clynes - Clontarf, IE
Dana L. Di Nino - North Andover MA, US
Padraig Doolan - Swords, IE
Patrick Gammell - Naas, IE
Kathleen Kopycinski - Somerville MA, US
Kevin M. McCarthy - North Andover MA, US
Paula Meleady - Ratoath, IE
Mark Melville - Melrose MA, US
Ryan Nolan - Stoneham MA, US

Assignee:

Wyeth - Madison NJ
Dublin City University - Dublin

International Classification:

C12Q 1/68
C12N 5/10

US Classification:

435 6, 435375, 435325

Abstract:

The present invention provides, among other things, systems and methods for identifying genes and proteins that regulate and/or are indicative of cell phenotypes based on expression profiling analysis. The present invention further provides methods of manipulating identified genes and proteins to engineer improved cell lines.

US Patent:

20090280559, Nov 12, 2009

Filed:

May 1, 2009

Appl. No.:

12/434425

Inventors:

Kevin McCarthy - Plaistow NH, US

Assignee:

KOLLMORGEN CORPORATION - Northampton MA

International Classification:

C12M 1/00
G05B 19/40
G02B 27/10
G03B 13/34

US Classification:

4352872, 318685, 359629, 396133

Abstract:

A fluorescence microscopy sequencer comprises a fluid transport subsystem in which reagents are pumped through a series of multi-port valves to a mixer or one or more flow cells, or directly into the flow cell(s). The one or more multi-port valves can be mounted upon a fluids manifold having syringe tubes mounted on the opposite side. Mounted on a movable support, the manifold may be brought into and out of fluid communication with a storage block comprising the plurality of reagents. In another embodiment, the sequencer comprises a beamsplitter indexer that facilitates the quick and reliable switching of filter cubes through use of a stepper motor. In yet another embodiment, a motion control system is provided in which an inertial reference is interposed between and directly coupled to a first and second axis of control, thereby minimizing any low structural resonant frequencies and enabling high performance (high frequency response) motion control.

US Patent:

20100132059, May 27, 2010

Filed:

Nov 10, 2009

Appl. No.:

12/615710

Inventors:

Kevin Michael MCCARTHY - Haverhill MA, US
Robin Allison Heller-Harrison - Andover MA, US
Mark William Leonard - Manchester NH, US
Timothy Shea Charlebois - Andover MA, US

Assignee:

Wyeth LLC - Madison NJ

International Classification:

A01K 67/00
C07K 2/00
C12N 5/10
C07H 21/00
C07H 21/04
C12N 15/74

US Classification:

800 13, 530300, 536 231, 435358, 536 245, 536 235, 536 241, 4353201

Abstract:

The present invention is based on the discovery that the transcriptional activity of both hamster mammary tumor 7 (HMT-7) and hamster layilin genes are increased when Chinese Hamster Ovary (CHO) cells are cultured at temperatures lower than 37 C. The present invention provides novel genomic, cDNA, and protein sequences of HMT-7 and a novel genomic sequence for hamster layilin. Included in the genomic sequences are novel temperature-induced promoter sequences for each; two promoter sequences are provided for HMT-7 and one promoter sequence is provided for layilin. The invention additionally provides antisense and siRNA molecules to the nucleic acid molecules of HMT-7. The invention also provides genetically engineered expression vectors comprising the novel temperature-induced promoters of the invention, which are particularly useful as part of a mammalian temperature-inducible expression system. The invention also provides host cells and/or transgenic animals comprising the novel nucleic acid molecules of the invention. The invention further provides methods of using the polynucleotides of the invention, e.g., for temperature-induced transgene expression.

US Patent:

20110014624, Jan 20, 2011

Filed:

Mar 12, 2009

Appl. No.:

12/921717

Inventors:

Kevin Michael McCarthy - Haverhill MA, US
Megan Jill Hone - Hudson NH, US
Robin Allison Heller-Harrison - Andover MA, US
Mark William Leonard - Manchester NH, US

Assignee:

Wyeth LLC - Madison NJ

International Classification:

C12Q 1/68
C12N 5/071

US Classification:

435 6, 435325

Abstract:

The present invention provides methods of identifying a clonal population of cells suitable for large-scale production of a protein of interest. The invention further provides methods for high-throughput screening for genetic rearrangements in the gene encoding the protein of interest, whereby the absence of a deletion in the gene encoding the protein of interest indicates that the cell is suitable for large-scale production of the protein of interest.

US Patent:

50058010, Apr 9, 1991

Filed:

Aug 18, 1989

Appl. No.:

7/395895

Inventors:

Martin A. Giarrocco - Upper Darby PA
Kevin J. McCarthy - Philadelphia PA

International Classification:

E04G 1718

US Classification:

249211

Abstract:

An apparatus and a method for holding, rotating and positioning a jack for the purpose of attaching said jack to one side of a structural support. The apparatus comprises a base and a holder. The base has a device to mount the base on the structural support. The holder is pivotally connected at one end to the base for displacement between a first location above said structural support and a second location at said one side. The holder has a receiver operable in a closed position to retain the jack as the holder is pivoted between said locations in order to position the jack for attachment to said one side of the structural support. The receiver is actuatable to an open position for removal of the holder from the jack after said attachment. The holder is displaceable from said second location back to said first location for removal of the apparatus from the support.