Kevin R Mcclay

US Patent:

7169591, Jan 30, 2007

Filed:

May 26, 2000

Appl. No.:

10/088991

Inventors:

Robert J. Steffan - Wrightstown PA, US
Kevin R. McClay - Hightstown NJ, US

Assignee:

Shaw Environmental & Infrastructure, Inc. - Lawrenceville NJ

International Classification:

C12P 17/00

US Classification:

435189, 435117, 435123, 435280, 435 41, 435132

Abstract:

A method for converting alkenes into epoxides and, particularly, to convert alkenes into enantio-specific epoxides by the use of enzymes which may be in their naturally-occuring (native) form or in mutated form, such as a native or mutated non-haem diiron-containing monooxygenase, and novel compounds produced thereby.

US Patent:

58145141, Sep 29, 1998

Filed:

Jul 10, 1996

Appl. No.:

8/677516

Inventors:

Robert Jon Steffan - Newtown PA
Charles Whitman Condee - Morrisville PA
Kevin Rock McClay - Morrisville PA
Jennifer Diane Michelson - Yardley PA
Mary F. DeFlaun - Mercerville NJ

Assignee:

Envirogen, Inc. - Lawrenceville NJ

International Classification:

C07C 0000

US Classification:

435262

Abstract:

The present invention is directed to a method for degrading an undesirable ether-based environmental contaminant by contacting the ether with a propane-oxidizing microorganism or with an isopropanol-oxidizing microorganism to convert the ether to innocuous compounds which are environmentally acceptable, including treating the ether-based contaminants in situ or removing them from the contaminated site for treatment in a bioreactor. Examples of ether-based compounds which can be degraded are tertiary butyl ethers of the type utilized as gasoline oxygenates, for example, methyl tert-butyl ether, ethyl tert-butyl ether, and methyl tert-amyl ether and also ether solvents, for example, tetrahydrofuran.

US Patent:

59587571, Sep 28, 1999

Filed:

Sep 13, 1996

Appl. No.:

8/713992

Inventors:

Robert Jon Steffan - Newtown PA
Kevin Rock McClay - Morrisville PA

Assignee:

Envirogen, Inc. - Lawrenceville NJ

International Classification:

B09B 300
C02F 334
C12N 100

US Classification:

4352625

Abstract:

Saturated aliphatic halocarbons, including environmental contaminants, are degraded to innocuous, environmentally acceptable compounds by contact, either in situ or in a bioreactor, with microorganisms that produce aromatic oxygenases, preferably with use of a co-substrate, for example, phenol, toluene, benzene, ethylbenzene and xylene, including the provision of novel bacteria that produce aromatic oxygenases, and new recombinant microorganisms that contain cloned aromatic oxygenase genes, examples of saturated aliphatic halocarbon that may be degraded to innocuous compounds being chloroform; bromoform; 1,2-dichloroethane; 1,2-dibromoethane; monochloroethane and monobromoethane.

US Patent:

63033666, Oct 16, 2001

Filed:

Aug 10, 1999

Appl. No.:

9/214751

Inventors:

Robert Jon Steffan - Newtown PA
Charles Whitman Condee - Morrisville PA
Kevin Rock McClay - Morrisville PA
Jennifer Diane Michelson - Yardley PA
Mary F. DeFlaun - Princeton NJ

Assignee:

Envirogen, Inc. - Lawrenceville NJ

International Classification:

C07C 0000

US Classification:

435262

Abstract:

Disclosed is a method for monitoring the degradation of methyl tert-butyl ether in a contaminated media which contains methyl tert-butyl ether and/or which is treated under conditions which cause the degradation of methyl tert-butyl ether into 2-hydroxy isobutyric acid comprising: (A) evaluating the treated contaminated media to determine the absence or presence therein of 2-hydroxy isobutyric acid; (B) based on such evaluation, determining whether the conditions should be modified; and (C) modifying such conditions as may be necessary. Disclosed also is a method for degrading an ether comprising contacting the ether with a microorganism that is effective in oxidizing propane or isopropanol and 2-hydroxy-isobutyric acid.