Kevin Quinton Taylor

US Patent:

20220387095, Dec 8, 2022

Filed:

May 17, 2022

Appl. No.:

17/746361

Inventors:

- San Carlos CA, US
William S. Krimsky - Forest Hill MD, US
Seth S. Gleiman - Guilford CT, US
Nicholas S. Mercer - San Francisco CA, US
Timothy J. O'Brien - Santa Clara CA, US
Quim Castellvi - Barcelona, ES
Jonathan R. Waldstreicher - West Orange NJ, US
Kevin J. Taylor - San Mateo CA, US
Luis L. Mangual Arbelo - Sunnyvale CA, US

Assignee:

Galvanize Therapeutics, Inc. - San Carlos CA

International Classification:

A61B 18/14
A61P 37/04
A61P 35/00

Abstract:

Damaged, diseased, abnormal, obstructive, cancerous or undesired neural tissue treated by delivering specialized pulsed electric field (PEF) energy to target tissue areas. In some instances, the target tissue includes a tumor, a benign tumor, a malignant tumor, a cyst, or an area of diseased tissue. Most brain and spinal cord tumors develop from glial cells. These tumors are sometimes referred to as a group called gliomas. They arise from the supporting cells of the brain, called the glia. These cells are subdivided into astrocytes, ependymal cells and oligodendroglial cells (or oligos). One difficulty in the treatment of gliomas is that they are behind the blood-brain barrier (BBB) and blood-tumor barrier (BTB) which leads to poor delivery of anti-cancer drugs or immune agents to the tumor-infiltrated brain. Devices, systems and methods are provided that treat the tumor directly, such as by ablation, and optionally transiently disrupt the BBB coupled with adjuvant antibody, biologic, or other pharmaceutical interventions.

US Patent:

20230082389, Mar 16, 2023

Filed:

Sep 9, 2022

Appl. No.:

17/941815

Inventors:

- San Carlos CA, US
William Sanford Krimsky - Forest Hill MD, US
Denise M. Zarins - Saratoga CA, US
Robert J. Beetel - Sunnyvale CA, US
Paul Brian Friedrichs - Belmont CA, US
Kevin James Taylor - San Mateo CA, US
Roman Turovskiy - San Francisco CA, US

Assignee:

Galvanize Therapeutics, Inc. - San Carlos CA

International Classification:

A61B 18/12
A61N 1/06

Abstract:

Apparatuses, systems and methods are provided for treating pulmonary tissues via delivery of energy, generally characterized by high voltage pulses, to target tissue using a pulmonary tissue modification system (e.g., an energy delivery catheter system). Example pulmonary tissues include, without limitation, the epithelium (the goblet cells, ciliated pseudostratified columnar epithelial cells, and basal cells), lamina propria, submucosa, submucosal glands, basement membrane, smooth muscle, cartilage, nerves, pathogens resident near or within the tissue, or a combination of any of these. The system may be used to treat a variety of pulmonary diseases or disorders such as or associated with COPD (e.g., chronic bronchitis, emphysema), asthma, interstitial pulmonary fibrosis, cystic fibrosis, bronchiectasis, primary ciliary dyskinesia (PCD), acute bronchitis and/or other pulmonary diseases or disorders.

US Patent:

20210236815, Aug 5, 2021

Filed:

Mar 25, 2021

Appl. No.:

17/212833

Inventors:

- San Carlos CA, US
William S. Krimsky - Forest Hill MD, US
Denise M. Zarins - Saratoga CA, US
Robert J. Beetel - Sunnyvale CA, US
Paul Brian Friedrichs - Belmont CA, US
Kevin James Taylor - San Mateo CA, US
Roman Turovskiy - San Francisco CA, US
Gary L. Long - Cincinnati OH, US

Assignee:

Galary, Inc. - San Carlos CA

International Classification:

A61N 1/32
A61N 1/05

Abstract:

Apparatuses, systems and methods are provided for treating pulmonary tissues via delivery of energy, generally characterized by high voltage pulses, to target tissue using a pulmonary tissue modification system (e.g., an energy delivery catheter system). Example pulmonary tissues include, without limitation, those within the respiratory tract, particularly the epithelium (the goblet cells, ciliated pseudostratified columnar epithelial cells, and basal cells), lamina propria, submucosa, submucosal glands, basement membrane, smooth muscle, cartilage, nerves, pathogens resident near or within the tissue, or a combination of any of these. The systems may be used to treat pathogens, such as bacteria and viruses, particularly coronaviruses.

US Patent:

20210236816, Aug 5, 2021

Filed:

Mar 26, 2021

Appl. No.:

17/214688

Inventors:

- San Carlos CA, US
William Sanford Krimsky - Forest Hill MD, US
Denise M. Zarins - Saratoga CA, US
Robert J. Beetel - Sunnyvale CA, US
Paul Brian Friedrichs - Belmont CA, US
Kevin James Taylor - San Mateo CA, US
Roman Turovskiy - San Francisco CA, US
Gary L. Long - Cincinnati OH, US

Assignee:

Galary, Inc. - San Carlos CA

International Classification:

A61N 1/32
A61N 1/06

Abstract:

Apparatuses, systems and methods are provided for treating pulmonary tissues via delivery of energy, generally characterized by high voltage pulses, to target tissue using a pulmonary tissue modification system (e.g., an energy delivery catheter system). Example pulmonary tissues include, without limitation, the epithelium (the goblet cells, ciliated pseudostratified columnar epithelial cells, and basal cells), lamina propria, submucosa, submucosal glands, basement membrane, smooth muscle, cartilage, nerves, pathogens resident near or within the tissue, or a combination of any of these. The system may be used to treat a variety of pulmonary diseases or disorders such as or associated with COPD (e.g., chronic bronchitis, emphysema), asthma, interstitial pulmonary fibrosis, cystic fibrosis, bronchiectasis, primary ciliary dyskinesia (PCD), acute bronchitis and/or other pulmonary diseases or disorders.

US Patent:

20210146126, May 20, 2021

Filed:

Jun 26, 2020

Appl. No.:

16/914072

Inventors:

- Menlo Park CA, US
William Sanford Krimsky - Forest Hill MD, US
Denise M. Zarins - Saratoga CA, US
Robert J. Beetel - Sunnyvale CA, US
Paul Brian Friedrichs - Belmont CA, US
Kevin James Taylor - San Mateo CA, US
Roman Turovskiy - San Francisco CA, US
Gary L. Long - Cincinnati OH, US

Assignee:

Galary, Inc. - Menlo Park CA

International Classification:

A61N 1/32
A61N 1/06

Abstract:

Apparatuses, systems and methods are provided for treating pulmonary tissues via delivery of energy, generally characterized by high voltage pulses, to target tissue using a pulmonary tissue modification system (e.g., an energy delivery catheter system). Example pulmonary tissues include, without limitation, the epithelium (the goblet cells, ciliated pseudostratified columnar epithelial cells, and basal cells), lamina propria, submucosa, submucosal glands, basement membrane, smooth muscle, cartilage, nerves, pathogens resident near or within the tissue, or a combination of any of these. The system may be used to treat a variety of pulmonary diseases or disorders such as or associated with COPD (e.g., chronic bronchitis, emphysema), asthma, interstitial pulmonary fibrosis, cystic fibrosis, bronchiectasis, primary ciliary dyskinesia (PCD), acute bronchitis and/or other pulmonary diseases or disorders.

US Patent:

20200323586, Oct 15, 2020

Filed:

Jun 10, 2020

Appl. No.:

16/898320

Inventors:

- Menlo Park CA, US
William Sanford KRIMSKY - Forest Hill MD, US
Denise Marie ZARINS - Saratoga CA, US
Paul Brian FRIEDRICHS - Belmont CA, US
Kevin James TAYLOR - San Mateo CA, US
Roman TUROVSKIY - San Francisco CA, US
Gary L. LONG - Cincinnati OH, US

Assignee:

Galary, Inc. - Menlo Park CA

International Classification:

A61B 18/14
A61B 18/12
A61N 1/06
A61N 1/32

Abstract:

Apparatuses, systems and methods are provided for treating pulmonary tissues via delivery of energy, generally characterized by high voltage pulses, to target tissue using a pulmonary tissue modification system (e.g., an energy delivery catheter system). Example pulmonary tissues include, without limitation, the epithelium (the goblet cells, ciliated pseudostratified columnar epithelial cells, and basal cells), lamina propria, submucosa, submucosal glands, basement membrane, smooth muscle, cartilage, nerves, pathogens resident near or within the tissue, or a combination of any of these. The system may be used to treat a variety of pulmonary diseases or disorders such as or associated with COPD (e.g., chronic bronchitis, emphysema), asthma, interstitial pulmonary fibrosis, cystic fibrosis, bronchiectasis, primary ciliary dyskinesia (PCD), acute bronchitis and/or other pulmonary diseases or disorders.

US Patent:

20190231425, Aug 1, 2019

Filed:

Apr 11, 2019

Appl. No.:

16/381745

Inventors:

- New York NY, US
William Sanford KRIMSKY - Forest Hill MD, US
Denise Marie ZARINS - Saratoga CA, US
Paul Brian FRIEDRICHS - Belmont CA, US
Kevin James TAYLOR - San Mateo CA, US
Roman TUROVSKIY - San Francisco CA, US
Gary L. LONG - Cincinnati OH, US

Assignee:

Gala Therapeutics, Inc. - New York NY

International Classification:

A61B 18/14
A61B 18/12

Abstract:

Apparatuses, systems and methods are provided for treating pulmonary tissues via delivery of energy, generally characterized by high voltage pulses, to target tissue using a pulmonary tissue modification system (e.g., an energy delivery catheter system). Example pulmonary tissues include, without limitation, the epithelium (the goblet cells, ciliated pseudostratified columnar epithelial cells, and basal cells), lamina propria, submucosa, submucosal glands, basement membrane, smooth muscle, cartilage, nerves, pathogens resident near or within the tissue, or a combination of any of these. The system may be used to treat a variety of pulmonary diseases or disorders such as or associated with COPD (e.g., chronic bronchitis, emphysema), asthma, interstitial pulmonary fibrosis, cystic fibrosis, bronchiectasis, primary ciliary dyskinesia (PCD), acute bronchitis and/or other pulmonary diseases or disorders.

US Patent:

20190201089, Jul 4, 2019

Filed:

Dec 20, 2018

Appl. No.:

16/227796

Inventors:

- New York NY, US
William Sanford KRIMSKY - Forest Hill MD, US
Denise Marie ZARINS - Saratoga CA, US
Paul Brian FRIEDRICHS - Belmont CA, US
Kevin James TAYLOR - San Mateo CA, US
Roman TUROVSKIY - San Francisco CA, US
Gary L. LONG - Cincinnati OH, US

International Classification:

A61B 18/14
A61B 18/12

Abstract:

Apparatuses, systems and methods are provided for treating pulmonary tissues via delivery of energy, generally characterized by high voltage pulses, to target tissue using a pulmonary tissue modification system (e.g., an energy delivery catheter system). Example pulmonary tissues include, without cells), lamina propria, submucosa, submucosal glands, basement membrane, smooth muscle, cartilage, nerves, pathogens resident near or within the tissue, or a combination of any of these. The system may be used to treat a variety of pulmonary diseases or disorders such as or associated with COPD (e.g., chronic bronchitis, emphysema), asthma, interstitial pulmonary fibrosis, cystic fibrosis, bronchiectasis, primary ciliary dyskinesia (PCD), acute bronchitis and/or other pulmonary diseases or disorders.