Kieran C O'Donoghue

US Patent:

20090234022, Sep 17, 2009

Filed:

Mar 12, 2009

Appl. No.:

12/381467

Inventors:

Christopher G. Salentine - San Rafael CA, US
Kieran O'Donoghue - San Mateo CA, US

Assignee:

Hana Biosciences, Inc. - South San Francisco CA

International Classification:

A61K 31/122
A61P 17/00

US Classification:

514681

Abstract:

The present invention provides topical formulations containing a vitamin K analog, e.g., menadione, that deliver a uniform, therapeutically effective concentration of the vitamin K analog to the skin in a vehicle which is stable, non-irritating, non-drying and cosmetically acceptable. These topical formulations are useful for the treatment and prevention of dermatological conditions associated with inflammation, particularly, dermatological conditions resulting from anti-EGFR therapies.

US Patent:

20140336268, Nov 13, 2014

Filed:

Jul 21, 2014

Appl. No.:

14/336876

Inventors:

- Irvine CA, US
Kieran O'Donoghue - San Mateo CA, US

International Classification:

A61K 47/14
A61K 9/00
A61K 31/122

US Classification:

514682

Abstract:

The present invention provides topical formulations containing a vitamin K analog, e.g., menadione, that deliver a uniform, therapeutically effective concentration of the vitamin K analog to the skin in a vehicle which is stable, non-irritating, non-drying and cosmetically acceptable. These topical formulations are useful for the treatment and prevention of dermatological conditions associated with inflammation, particularly, dermatological conditions resulting from anti-EGFR therapies.