Krzysztof Z Lazarski

age ~61

from Darien, IL

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Automatic Cryoloop Alignment For Protein Crystals
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US Patent:

7438472, Oct 21, 2008
Filed:

Jul 9, 2007
Appl. No.:

11/774679
Inventors:

Krzysztof Z. Lazarski - Darien IL, US
Andrzej Joachimiak - Bolingbrook IL, US
Assignee:

UChicago Argonne, LLC - Chicago IL
International Classification:

A61B 6/08
US Classification:

378205, 378 73, 378 985
Abstract:

Methods and apparatus for implementing robust and efficient cryoloop auto-centering for crystal location and alignment to the x-ray beam are provided. Image processing techniques are used for recognition of the small protein crystals. The detected crystal location enables crystal positioning in the x-ray beam, and optimization of the x-ray optics such as beam profile and intensity to the size and shape of the protein crystals.