Ranjan K Sen

US Patent:

6410516, Jun 25, 2002

Filed:

Jun 5, 1995

Appl. No.:

08/464364

Inventors:

David Baltimore - New York NY
Ranjan Sen - Cambridge MA
Phillip A. Sharp - Newton MA
Harinder Singh - Chicago IL
Louis Staudt - Silver Springs MD
Jonathan H. Lebowitz - Zionsville IN
Roger G. Clerc - Binningen, CH
Lynn M. Corcoran - Port Melbourne, AU
Patrick A. Baeuerle - Eichenau, DE
Michael J. Lenardo - Potomac MD
Chen-Ming Fan - San Francisco MA
Thomas P. Maniatis - Belmont MA

Assignee:

President Fellows of Harvard College - Cambridge MA
Massachusetts Institute of Technology - Cambridge MA
Whitehead Instittue for Biomedical Research - Cambridge MA

International Classification:

A61K 31711

US Classification:

514 44, 435 6, 435455, 435325, 435366, 435370, 435372, 4353722, 4353723

Abstract:

Constitutive and tissue-specific protein factors which bind to transcriptional regulatory elements of Ig genes (promoter and enhancer) are described. The factors were identified and isolated by an improved assay for protein-DNA binding. Genes encoding factors which positively regulate transcription can be isolated and employed to enhance transription of Ig genes. In particular, NF-kB, the gene encoding NF-kB, IkB and the gene encoding IkB and uses therefor.

US Patent:

20040214757, Oct 28, 2004

Filed:

Jan 4, 2002

Appl. No.:

10/037341

Inventors:

David Baltimore - New York NY, US
Ranjan Sen - Cambridge MA, US
Phillip Sharp - Newton MA, US
Harinder Singh - Chicago IL, US
Louis Staudt - Silver Springs MD, US
Jonathan LeBowitz - Zionsville IN, US
Albert Baldwin - Chapel Hill NC, US
Roger Clerc - Binningen, CH
Lynn Corcoran - Port Melbourne, AU
Patrick Baeuerle - Eichenau, DE
Michael Lenardo - Potomac MD, US
Chen-Ming Fan - San Francisco MA, US
Thomas Maniatis - Belmont MA, US

International Classification:

C07K014/47
C07H021/04

US Classification:

514/012000, 530/358000, 536/023500

Abstract:

Constitutive and tissue-specific protein factors which bind to transcriptional regulatory elements of Ig genes (promoter and enhancer) are described. The factors were identified and isolated by an improved assay for protein-DNA binding. Genes encoding factors which positively regulate transcription can be isolated and employed to enhance transcription of Ig genes. In particular, NF-kB, the gene encoding NF-kB, IkB and the gene encoding IkB and uses therefor.

US Patent:

20060063709, Mar 23, 2006

Filed:

Jan 4, 2002

Appl. No.:

10/037415

Inventors:

David Baltimore - New York NY, US
Ranjan Sen - Cambridge MA, US
Phillip Sharp - Newton MA, US
Harinder Singh - Chicago IL, US
Louis Staudt - Silver Springs MD, US
Jonathan LeBowitz - Zionsville, IN
Albert Baldwin - Chapel Hill NC, US
Roger Clerc - Binningen, CH
Lynn Corcoran - Port Melbourne, AU
Patrick Baeuerle - Eichenau, DE
Michael Lenardo - Potomac MD, US
Chen-Ming Fan - San Francisco CA, US
Thomas Maniatis - Belmont CA, US

International Classification:

A61K 38/17
C07K 14/47
C07H 21/04

US Classification:

514012000, 530358000, 536023500

Abstract:

Constitutive and tissue-specific protein factors which bind to transcriptional regulatory elements of Ig genes (promoter and enhancer) are described. The factors were identified and isolated by an improved assay for protein-DNA binding. Genes encoding factors which positively regulate transcription can be isolated and employed to enhance transcription of Ig genes. In particular, NF-kB, the gene encoding NF-kB, IkB and the gene encoding IkB and uses therefor.

US Patent:

20130054293, Feb 28, 2013

Filed:

Aug 21, 2012

Appl. No.:

13/590580

Inventors:

Nayana Sen - Saint Augustine FL, US
Ranjan Kumar Sen - Orange Park FL, US

International Classification:

G06Q 10/10

US Classification:

705 718

Abstract:

A process for matching event planners with vendors using real-time information. with the steps of: a server having a memory configured to store data and instructions, a database stored in the memory and accessed by vendors and event planners through a website and, a processor associated with the server and configured to execute instructions to: receive and store in the database profiles of a plurality of vendors, receive and store in the database criteria of planner, Method, in response to the profile of the planner, access the database and match the planner with at least one vendor having a profile that meets at least one criteria of the planner, receive an input from the planner indicating one or more vendors the event planner would like to obtain more information from, and in response to the planner accepting contact by the selected vendors, transmit an e-mail notification to the selected vendors.

US Patent:

61500909, Nov 21, 2000

Filed:

Jun 5, 1995

Appl. No.:

8/463397

Inventors:

David Baltimore - New York NY
Ranjan Sen - Cambridge MA
Phillip A. Sharp - Newton MA
Harinder Singh - Chicago IL
Louis Staudt - Silver Springs MD
Jonathan H. LeBowitz - Zionsville IN
Albert S. Baldwin - Chapel Hill NC
Roger G. Clerc - Binningen, CH
Lynn M. Corcoran - Port Melbourne, AU
Patrick A. Baeuerle - Eichenau, DE
Michael J. Lenardo - Potomac MD
Chen-Ming Fan - San Francisco MA
Thomas P. Maniatis - Belmont MA

Assignee:

Massachusetts Institute of Technology - Cambridge MA
Whitehead Institute - Cambridge MA
President and Fellows of Harvard College - Cambridge MA

International Classification:

C12Q 102
C12Q 168
G01N 3353

US Classification:

435 6

Abstract:

Constitutive and tissue-specific protein factors which bind to transcriptional regulatory elements of Ig genes (promoter and enhancer) are described. The factors were identified and isolated by an improved assay for protein-DNA binding. Genes encoding factors which positively regulate transcription can be isolated and employed to enhance transription of Ig genes. In particular, NF-kB, the gene encoding NF-kB, IkB and the gene encoding IkB and uses therefor.

US Patent:

58043748, Sep 8, 1998

Filed:

Apr 6, 1995

Appl. No.:

8/418266

Inventors:

David Baltimore - New York NY
Ranjan Sen - Cambridge MA
Phillip A. Sharp - Newton MA
Harinder Singh - Chicago IL
Louis Staudt - Silver Springs MD
Jonathan H. LeBowitz - Zionsville IN
Albert S. Baldwin - Chapel Hill NC
Roger G. Clerc - Binningen, CH
Lynn M. Corcoran - Victoria, AU
Patrick A. Baeuerle - Eichenau, DE
Michael J. Lenardo - Potomac MD
Chen-Ming Fan - San Francisco MA
Thomas P. Maniatis - Belmont MA

Assignee:

Massachusetts Insti. Technology - Cambridge MA
Whitehead Insti. - Cambridge MA
Pres. and Fellow of Harvard College - Cambridge MA

International Classification:

C12Q 168
C12N 1511

US Classification:

435 6

Abstract:

Constitutive and tissue-specific protein factors which bind to transcriptional regulatory elements of Ig genes (promoter and enhancer) are described. The factors were identified and isolated by an improved assay for protein-DNA binding. Genes encoding factors which positively regulate transcription can be isolated and employed to enhance transription of Ig genes. In particular, NF-kB, the gene encoding NF-kB, IkB and the gene encoding IkB and uses therefor.