Larry S Green

US Patent:

6354244, Mar 12, 2002

Filed:

Sep 16, 1999

Appl. No.:

09/397482

Inventors:

Larry Green - Redmond WA 98052

International Classification:

A01K 3100

US Classification:

119429

Abstract:

A modular garden accessory system. This system comprises a post assembly, one or more branch assemblies, and one or more garden accessories that may be connected to or suspended from the post assembly or the branch assemblies. The system is comprised of a relatively small number of standard parts that may be connected in a number of configurations to obtain a relatively large number of accessories. The system is designed for easy assembly with a minimum number of fasteners. Many of the accessories are constructed about a plastic base member that defines an upper surface appropriate for use as a feeder and a lower surface that allows the accessory to be attached to a post assembly or branch assembly in one of a number of configurations.

US Patent:

8114965, Feb 14, 2012

Filed:

Nov 7, 2007

Appl. No.:

11/983372

Inventors:

Paul J. Maddon - Scarsdale NY, US
Gerald P. Donovan - New York NY, US
William C. Olson - Ossining NY, US
Norbert Schuelke - Dedham MA, US
Jason Gardner - Merseyside, GB
Dangshe Ma - Milwood NY, US
Jaspal S. Kang - Surrey, CA
Larry Green - San Francisco CA, US

Assignee:

PSMA Development Company, LLC - Tarrytown NY
Amgen Fremont Inc. - Fremont CA

International Classification:

C07K 16/18

US Classification:

5303871, 5303917, 5303873, 5303877, 5303888, 5303913, 536 235, 4353201, 435325, 435 691, 435328, 435330

Abstract:

The invention includes antibodies or antigen-binding fragments thereof which bind specifically to conformational epitopes on the extracellular domain of PSMA, compositions containing one or a combination of such antibodies or antigen-binding fragments thereof, hybridoma cell lines that produce the antibodies, and methods of using the antibodies or antigen-binding fragments thereof for cancer diagnosis and treatment. The invention also includes oligomeric forms of PSMA proteins, compositions comprising the multimers, and antibodies that selectively bind to the multimers.

US Patent:

8470330, Jun 25, 2013

Filed:

Jul 28, 2010

Appl. No.:

12/845686

Inventors:

Paul J. Maddon - Scarsdale NY, US
Gerald P. Donovan - Kittery ME, US
William C. Olson - Yorktown Heights NY, US
Norbert Schuelke - East Walpole MA, US
Jason Gardner - Wayne PA, US
Dangshe Ma - Millwood NY, US
Jaspal S. Kang - Surrey, CA
Larry Green - San Francisco CA, US

Assignee:

PSMA Development Company, LLC - Tarrytown NY
Amgen Fremont Inc. - Thousand Oaks CA

International Classification:

A61K 39/00
A61K 39/395

US Classification:

4241831, 4241301, 4241331, 4241381, 4241551, 4241741, 4241781, 4241811, 530350, 5303871, 5303873, 5303877, 5303888, 5303913, 5303917

Abstract:

The invention includes stable multimeric, particularly dimeric, forms of PSMA protein, compositions and kits containing dimeric PSMA protein as well as methods of producing, purifying and using these compositions. Such methods include methods for eliciting or enhancing an immune response to cells expressing PSMA, including methods of producing antibodies to dimeric PSMA, as well as methods of treating cancer, such as prostate cancer.

US Patent:

20150197577, Jul 16, 2015

Filed:

Sep 10, 2012

Appl. No.:

13/608337

Inventors:

Paul J. Maddon - Scarsdale NY, US
Gerald P. Donovan - Kittery ME, US
William C. Olson - Yorktown Heights NY, US
Norbert Schuelke - East Walpole MA, US
Jason Gardner - Wayne PA, US
Dangshe Ma - Millwood NY, US
Jaspal S. Kang - Surrey, CA
Larry Green - San Francisco CA, US

Assignee:

PSMA Development Company, LLC - Tarrytown NY
Amgen Fremont Inc. - Thousand Oaks CA

International Classification:

C07K 16/40
A61K 51/10
G01N 33/574

Abstract:

The invention includes stable multimeric, particularly dimeric, forms of PSMA protein, compositions and kits containing dimeric PSMA protein as well as methods of producing, purifying and using these compositions. Such methods include methods for eliciting or enhancing an immune response to cells expressing PSMA, including methods of producing antibodies to dimeric PSMA, as well as methods of treating cancer, such as prostate cancer.