Larry V Walker

US Patent:

20100317078, Dec 16, 2010

Filed:

Aug 27, 2008

Appl. No.:

12/675881

Inventors:

Manuel J. Villa-Garcia - Ithaca NY, US
Erin J. Krause - Baldwinsville NY, US
Larry P. Walker - Ithaca NY, US
Susan A. Henry - Ithaca NY, US

International Classification:

C12P 7/06
C12N 1/16
C12N 15/81
C12P 7/02

US Classification:

435161, 4352551, 4352554, 4352555, 4352552, 435471, 435155

Abstract:

The present invention is directed to a method of producing organisms tolerant to alcohol, that includes selecting a microorganism needing tolerance to alcohol and modifying the selected microorganism under conditions effective to overproduce inositol by the microorganism compared to when the microorganism is not modified, with the modified microorganism being tolerant to alcohol. The present invention is also directed to a method of producing alcohol that includes providing a microorganism tolerant to alcohol which is modified to overproduce inositol by the microorganism compared to when the microorganism is not modified. A fermentable feedstock is treated with the modified microorganism under conditions effective to produce the alcohol. The modified microorganism is also able to produce and tolerate alcohol in high osmolarity feedstocks.

US Patent:

20130017579, Jan 17, 2013

Filed:

Mar 10, 2011

Appl. No.:

13/638338

Inventors:

Jeremy Luterbacher - Ithaca NY, US
Larry P. Walker - Ithaca NY, US
Jefferson W. Tester - Hingham MA, US

Assignee:

CORNELL UNIVERSITY - Ithaca NY

International Classification:

C12P 19/14
C09K 3/00
C12P 7/06

US Classification:

435 99, 435161, 25218212

Abstract:

A process for pretreatment of a biomass material, comprising subjecting a biomass material to a biphasic mixture of water and supercritical COat a temperature in the range of 150 C. to 250 C. under high pressure for a time of from 10 seconds to 100 minutes. In particular embodiments, the process is performed as a two-stage temperature process wherein an initial short high-temperature stage is conducted at a temperature of at least 200 C. for up to 20 minutes and a subsequent longer low-temperature stage is conducted at a temperature of at least 140 C. and up to 190 C. for 10-120 minutes.

US Patent:

20140004583, Jan 2, 2014

Filed:

Mar 9, 2012

Appl. No.:

14/004311

Inventors:

Stephane C. Corgie - Ithaca NY, US
Patarawan Kahawong - Nakhonsithammarat, TH
Emmanuel P. Giannelis - Ithaca NY, US
Larry P. Walker - Ithaca NY, US

Assignee:

CORNELL UNIVERSITY - Ithaca NY

International Classification:

B01J 31/00
C02F 3/34

US Classification:

435156, 435176, 210632

Abstract:

A composition comprising mesoporous aggregates of magnetic nanoparticles and free-radical producing enzyme (i.e., enzyme-bound mesoporous aggregates), wherein the mesoporous aggregates of magnetic nanoparticles have mesopores in which the free-radical-producing enzyme is embedded. Methods for synthesizing the enzyme-bound mesoporous aggregates are also described. Processes that use said enzyme-bound mesoporous aggregates for depolymerizing lignin, removing aromatic contaminants from water, and polymerizing monomers polymerizable by a free-radical reaction are also described.

US Patent:

56771517, Oct 14, 1997

Filed:

Jun 24, 1994

Appl. No.:

8/265429

Inventors:

David B. Wilson - Ithaca NY
Larry P. Walker - Ithaca NY
Sheng Zhang - Ithaca NY

Assignee:

Cornell Research Foundation, Inc. - Ithaca NY

International Classification:

C12P 1920
C12N 926
A61K 3847
C07H 2104

US Classification:

435 72

Abstract:

The invention relates to a gene isolated from Thermomonospora fusca, wherein the gene encodes a thermostable cellulase. Disclosed is the nucleotide sequence of the T. fusca gene; and nucleic acid molecules comprising the gene, or a fragment of the gene, that can be used to recombinantly express the cellulase or a catalytically active polypeptide thereof, respectively. The isolated and purified recombinant cellulase or catalytically active polypeptide may be used to hydrolyze substrate either by itself; or in combination with other cellulases, with the resultant combination having unexpected hydrolytic activity.

US Patent:

46567690, Apr 14, 1987

Filed:

Mar 13, 1984

Appl. No.:

6/588942

Inventors:

Larry L. Walker - Lakewood CO

International Classification:

A01K 9700
D03J 300

US Classification:

43 1

Abstract:

A device for use in the assembly of fishing flies and in particular the attachment of loose dubbing material to the thread used in making the fishing fly is disclosed. The device comprises an elongated rod which has positioned around a portion of the rod means for holding the rod while permitting the rod to be rotated as desired. On one end of the rod is attached rotating means for rotating the rod at predetermined speeds within the holding means. The other end of the elongated rod has formed thereon gripping means for gripping the thread used in the assembly of the fishing fly in a spaced apart manner. The dubbing is positioned between the spaced apart thread and the elongated rod may be rotated to tightly wrap the thread around a portion of the dubbing. The method for attaching dubbing to a thread using the applicants device is also disclosed. The device may be used in a modified form as a conversation piece and as a pacifier for nervous people such as executives.

US Patent:

20220213464, Jul 7, 2022

Filed:

Jan 28, 2022

Appl. No.:

17/587006

Inventors:

- Ithaca NY, US
Xiaonan DUAN - Ithaca NY, US
Emmanuel GIANNELIS - Ithaca NY, US
Daniel ANESHANSLEY - Ithaca NY, US
Larry P. WALKER - Ithaca NY, US

Assignee:

CORNELL UNIVERSITY - Ithaca NY

International Classification:

C12N 11/04
A62D 3/02
B01J 19/12
B01J 35/04
B01J 37/02
C02F 1/48
C02F 3/00
C02F 3/34
C07C 1/12
C07G 1/00
C08F 14/00
C08F 18/00
C07D 301/22
C12N 11/14
C12P 7/22
C12N 9/02
C12N 9/04
C12N 9/08
C12N 13/00
C12P 7/04
C12P 17/02
B01J 31/00
B01J 35/00
C12N 11/098
C12N 11/091
C12N 11/08
B01J 31/02
B01J 8/00

Abstract:

A hierarchical catalyst composition comprising a continuous or particulate macroporous scaffold in which is incorporated mesoporous aggregates of magnetic nanoparticles, wherein an enzyme is embedded in mesopores of the mesoporous aggregates of magnetic nanoparticles. Methods for synthesizing the hierarchical catalyst composition are also described. Also described are processes that use the recoverable hierarchical catalyst composition for depolymerizing lignin, remediation of water contaminated with aromatic substances, polymerizing monomers by a free-radical mechanism, epoxidation of alkenes, halogenation of phenols, inhibiting growth and function of microorganisms in a solution, and carbon dioxide conversion to methanol. Further described are methods for increasing the space time yield and/or total turnover number of a liquid-phase chemical reaction that includes magnetic particles to facilitate the chemical reaction, the method comprising subjecting the chemical reaction to a plurality of magnetic fields of selected magnetic strength, relative position in the chemical reaction, and relative motion.

US Patent:

20210047630, Feb 18, 2021

Filed:

Aug 28, 2020

Appl. No.:

17/005962

Inventors:

- Ithaca NY, US
Xiaonan DUAN - Ithaca NY, US
Emmanuel GIANNELIS - Ithaca NY, US
Daniel ANESHANSLEY - Ithaca NY, US
Larry P. WALKER - Ithaca NY, US

Assignee:

CORNELL UNIVERSITY - Ithaca NY

International Classification:

C12N 11/04
A62D 3/02
B01J 19/12
B01J 35/04
B01J 37/02
C02F 1/48
C02F 3/00
C02F 3/34
C07C 1/12
C07G 1/00
C08F 14/00
C08F 18/00
C07D 301/22
C12N 11/14
C12P 7/22
C12N 9/02
C12N 9/04
C12N 9/08
C12N 13/00
C12P 7/04
C12P 17/02
B01J 31/00
B01J 35/00
B01J 31/02
B01J 8/00
C12N 11/08

Abstract:

A hierarchical catalyst composition comprising a continuous or particulate macroporous scaffold in which is incorporated mesoporous aggregates of magnetic nanoparticles, wherein an enzyme is embedded in mesopores of the mesoporous aggregates of magnetic nanoparticles. Methods for synthesizing the hierarchical catalyst composition are also described. Also described are processes that use the recoverable hierarchical catalyst composition for depolymerizing lignin, remediation of water contaminated with aromatic substances, polymerizing monomers by a free-radical mechanism, epoxidation of alkenes, halogenation of phenols, inhibiting growth and function of microorganisms in a solution, and carbon dioxide conversion to methanol. Further described are methods for increasing the space time yield and/or total turnover number of a liquid-phase chemical reaction that includes magnetic particles to facilitate the chemical reaction, the method comprising subjecting the chemical reaction to a plurality of magnetic fields of selected magnetic strength, relative position in the chemical reaction, and relative motion.

US Patent:

20200002698, Jan 2, 2020

Filed:

Jun 27, 2019

Appl. No.:

16/454714

Inventors:

- Ithaca NY, US
Xiaonan DUAN - Ithaca NY, US
Emmanuel GIANNELIS - Ithaca NY, US
Daniel ANESHANSLEY - Ithaca NY, US
Larry P. WALKER - Ithaca NY, US

Assignee:

CORNELL UNIVERSITY - Ithaca NY

International Classification:

C12N 11/04
A62D 3/02
B01J 19/12
B01J 35/04
B01J 37/02
C02F 1/48
C02F 3/00
C02F 3/34
C07C 1/12
C07G 1/00
C08F 14/00
C08F 18/00
C07D 301/22
C12N 11/14
C12P 7/22
C12N 9/02
C12N 9/04
C12N 9/08
C12N 13/00
C12P 7/04
C12P 17/02
B01J 31/00
B01J 35/00
B01J 31/02
B01J 8/00
C12N 11/08

Abstract:

A hierarchical catalyst composition comprising a continuous or particulate macroporous scaffold in which is incorporated mesoporous aggregates of magnetic nanoparticles, wherein an enzyme is embedded in mesopores of the mesoporous aggregates of magnetic nanoparticles. Methods for synthesizing the hierarchical catalyst composition are also described. Also described are processes that use the recoverable hierarchical catalyst composition for depolymerizing lignin remediation of water contaminated with aromatic substances, polymerizing monomers by a free-radical mechanism, epoxidation of alkenes, halogenation of phenols, inhibiting growth and function of microorganisms in a solution, and carbon dioxide conversion to methanol. Further described are methods for increasing the space time yield and/or total turnover number of a liquid-phase chemical reaction that includes magnetic particles to facilitate the chemical reaction, the method comprising subjecting the chemical reaction to a plurality of magnetic fields of selected magnetic strength, relative position in the chemical reaction, and relative motion.