- New York NY, US Reid Martin Renny Feldman - San Francisco CA, US Ling Hon Matthew Chu - San Jose CA, US Javier Fernando Chaparro Riggers - San Mateo CA, US Ivana Djuretic - San Bruno CA, US Laura Lin - Weston MA, US Lidia Mosyak - Newton MA, US
The present invention relates to human interleukin 15 (IL-15) variants that have therapeutic and diagnostic use, and methods for making thereof. The present invention also provides fusion proteins comprising a human IL-15 variant. Also provided are methods of stimulating or suppressing immune responses in a mammal, and methods of treating a disorder (e.g., cancer) using the IL-15 variants or the fusion protein of such IL-15 variants.
- New York NY, US Reid Martin Renny Feldman - San Francisco CA, US Ling Hon Matthew Chu - San Jose CA, US Javier Fernando Chaparro Riggers - San Mateo CA, US Ivana Djuretic - San Bruno CA, US Laura Lin - Weston MA, US Lidia Mosyak - Newton MA, US
The present invention relates to human interleukin 15 (IL-15) variants that have therapeutic and diagnostic use, and methods for making thereof. The present invention also provides fusion proteins comprising a human IL-15 variant. Also provided are methods of stimulating or suppressing immune responses in a mammal, and methods of treating a disorder (e.g., cancer) using the IL-15 variants or the fusion protein of such IL-15 variants.