Laurie Ann Joseph

US Patent:

20030114520, Jun 19, 2003

Filed:

Aug 9, 2002

Appl. No.:

10/215832

Inventors:

Abel Pereira - Belleville NJ, US
Laurie Joseph - Monroe Township NJ, US
Robert Comber - New City NY, US

Assignee:

Croda, Inc. - Parsippany NJ

International Classification:

A61K031/235
A61K031/225
C07C069/76
C07C069/34
C07C069/52

US Classification:

514/532000, 514/547000, 560/089000, 560/198000

Abstract:

Alkoxylated esters of dicarboxylic or tricarboxylic acids have an anti-irritating activity measured as a reduction in intracellular leakage of sodium fluorescein of 15% or more at 1:50 dilution or 40% or more at 1:100 dilution from a test composition containing 5% of the alkoxylated ester. These alkoxylated esters are useful in cosmetic and personal care products, especially in products such as baby shampoos, hand dishwashing liquids and bubble bath preparations. A method of reducing irritation provides for application of an irritant with the alkoxylated esters to the subject in a personal care or cosmetic product.

US Patent:

20080039405, Feb 14, 2008

Filed:

Apr 20, 2007

Appl. No.:

11/788759

Inventors:

Nigel Langley - Belle Mead NJ, US
Abel Pereira - Bridgewater NJ, US
Laurie Joseph - Monroe Township NJ, US

Assignee:

Croda, Inc. - Edison NJ

International Classification:

A61K 31/075
A61K 31/01
A61K 31/185
A61K 31/35
A61K 31/415
A61K 31/70
A61K 31/56
A61K 31/355
A61K 31/315
A61K 31/07

US Classification:

514029000, 514169000, 514396000, 514456000, 514458000, 514494000, 514576000, 514714000, 514717000, 514725000, 514762000

Abstract:

The present invention relates to methods of influencing the flux or surface retention time of a topically active pharmaceutical ingredient through skin and formulations relating thereto.