Lei Zhu

US Patent:

7332343, Feb 19, 2008

Filed:

Jan 14, 2005

Appl. No.:

11/036642

Inventors:

Eric V. Anslyn - Austin TX, US
Lei Zhu - Tallahassee FL, US

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

G01N 33/00
C07D 209/82
C07D 209/94
C07D 251/00

US Classification:

436 86, 435 792, 435 793, 548439, 544218

Abstract:

The invention includes an enantioselective indicator-displacement assay useful to determine enantiomeric excess (ee) enantiomeric samples calorimetrically. Determination may be by inspection of color with the naked eye, spectrographic measurement, or mathematical calculation. Concentration may also be determined. The assay may involve two independent absorption measurements. On suitable group of enantiomeric molecules to be assayed include α-hydroxyacids. The inherent relationship between the absorbance of the indicator-displacement ensemble and the overall concentration and ee of the analyte is established through solution equilibria. The invention also includes use of the assay in drug screening and manufacturing, high throughput screening of catalysts and kits for use in conducting assays of the invention.

US Patent:

7479548, Jan 20, 2009

Filed:

May 28, 2004

Appl. No.:

10/855893

Inventors:

James Wayne Canary - New York NY, US
Nadrian C. Seeman - New York NY, US
Lei Zhu - Austin TX, US
Philip Lukeman - New York NY, US

Assignee:

New York University - New York NY

International Classification:

C07H 21/04
C07H 21/00
C07K 2/00

US Classification:

536 231, 536 253, 536 243, 530300

Abstract:

The present invention relates to a copolymer termed a ladder copolymer because it has two backbones that serve as legs/sides of a ladder structure. These two backbones, one of which is a nucleic acid or nucleic acid-like polymer, are linked together as the legs/sides of a ladder are linked together by the rungs.

US Patent:

7670847, Mar 2, 2010

Filed:

Aug 15, 2007

Appl. No.:

11/839085

Inventors:

Eric V. Anslyn - Austin TX, US
Lei Zhu - Austin TX, US

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

G01N 21/00
G01N 33/00
B01D 15/08

US Classification:

436164, 436 86, 435 792, 435 793, 564424

Abstract:

The invention includes an enantioselective indicator-displacement assay useful to determine enantiomeric excess (ee) enantiomeric samples colorimetrically. Determination may be by inspection of color with the naked eye, spectrographic measurement, or mathematical calculation. Concentration may also be determined. The assay may involve two independent absorption measurements. On suitable group of enantiomeric molecules to be assayed include α-hydroxy acids. The inherent relationship between the absorbance of the indicator-displacement ensemble and the overall concentration and ee of the analyte is established through solution equilibria. The invention also includes use of the assay in drug screening and manufacturing, high throughput screening of catalysts and kits for use in conducting assays of the invention.

US Patent:

7943751, May 17, 2011

Filed:

Dec 8, 2008

Appl. No.:

12/330250

Inventors:

James Wayne Canary - New York NY, US
Nadrian C. Seeman - New York NY, US
Lei Zhu - Austin TX, US
Philip Lukeman - New York NY, US

Assignee:

New York University - New York NY

International Classification:

C07H 21/04
C07H 21/00
C07K 2/00

US Classification:

536 231, 536 253, 536 243, 530300

Abstract:

The present invention relates to a copolymer termed a ladder copolymer because it has two backbones that serve as legs/sides of a ladder structure. These two backbones, one of which is a nucleic acid or nucleic acid-like polymer, are linked together as the legs/sides of a ladder are linked together by the rungs.

US Patent:

20200177167, Jun 4, 2020

Filed:

Feb 7, 2020

Appl. No.:

16/784392

Inventors:

- Edinburgh, GB
Tejasvi DAS - Austin TX, US
Xin ZHAO - Austin TX, US
Lei ZHU - Austin TX, US
Xiaofan FEI - Austin TX, US

Assignee:

Cirrus Logic International Semiconductor Ltd. - Edinburgh

International Classification:

H03K 3/01
H03K 17/687

Abstract:

A driver system may include a first n-type field-effect transistor coupled at its non-gate terminals between an output of the driver system and a first terminal of a supply voltage and configured to drive the output when the first n-type field-effect transistor is activated, a second n-type field-effect transistor coupled at its non-gate terminals between an output of the driver system and a second terminal of the supply voltage and configured to drive the output when the second n-type field-effect transistor is activated, a high-side capacitor coupled to the output of the driver system, and a low-side capacitor coupled to the second terminal of the supply voltage, wherein the high-side capacitor and the low-side capacitor are configured to track and correct for mismatches between a first resistance of the first n-type field-effect transistor and a second resistance of the second n-type field-effect transistor.

US Patent:

20200044616, Feb 6, 2020

Filed:

Nov 14, 2018

Appl. No.:

16/190427

Inventors:

- Edinburgh, GB
Eric J. KING - Austin TX, US
Xin ZHAO - Austin TX, US
Xiaofan FEI - Austin TX, US
Johann G. GABORIAU - Austin TX, US
Lei ZHU - Austin TX, US
John L. MELANSON - Austin TX, US
Thomas HOFF - Austin TX, US

Assignee:

Cirrus Logic International Semiconductor Ltd. - Edinburgh

International Classification:

H03F 3/393
H03F 3/217
H03F 3/187
H03G 3/30

Abstract:

A system may include a digital modulator configured to modulate an input signal received at an input of the digital modulator to generate a modulated input signal at an output of the digital modulator, a digital gain element having a digital gain and coupled to the digital modulator, an open-loop Class-D amplifier coupled to an output of the digital modulator and configured to amplify the modulated input signal, wherein the open-loop Class-D amplifier is powered from a variable power supply having a variable supply voltage which is variable in response to one or more characteristics of the input signal, and a control circuit configured to control the digital gain to approximately cancel changes in an analog gain of the open-loop Class-D amplifier due to variation in the variable supply voltage in response to the one or more characteristics of the input signal.

US Patent:

20200021289, Jan 16, 2020

Filed:

Sep 25, 2019

Appl. No.:

16/582528

Inventors:

- Edinburgh, GB
Lei ZHU - Austin TX, US
Kyehyung LEE - Austin TX, US

Assignee:

Cirrus Logic International Semiconductor Ltd. - Edinburgh

International Classification:

H03K 19/00
H03G 1/00

Abstract:

In accordance with embodiments of the present disclosure, a system may include a buffer and a switch coupled between the buffer and a voltage supply such that the switch controls a varying voltage at a varying voltage node coupled to the buffer.

US Patent:

20190260377, Aug 22, 2019

Filed:

Oct 17, 2018

Appl. No.:

16/162960

Inventors:

- Edinburgh, GB
Tejasvi DAS - Austin TX, US
Xin ZHAO - Austin TX, US
Lei ZHU - Austin TX, US
Xiaofan FEI - Austin TX, US

Assignee:

Cirrus Logic International Semiconductor Ltd. - Edinburgh

International Classification:

H03K 17/687
H03K 17/06
G06F 3/01

Abstract:

A driver system may include a first n-type field-effect transistor coupled at its non-gate terminals between an output of the driver system and a first terminal of a supply voltage and configured to drive the output when the first n-type field-effect transistor is activated, a second n-type field-effect transistor coupled at its non-gate terminals between an output of the driver system and a second terminal of the supply voltage and configured to drive the output when the second n-type field-effect transistor is activated, a high-side capacitor coupled to the output of the driver system, and a low-side capacitor coupled to the second terminal of the supply voltage, wherein the high-side capacitor and the low-side capacitor are configured to track and correct for mismatches between a first resistance of the first n-type field-effect transistor and a second resistance of the second n-type field-effect transistor.

Address:

4925 Pyrenees Pass, Austin, TX 78738

VIN:

WVWLK73C77E005540

Make:

VOLKSWAGEN

Model:

PASSAT

Year:

2007