Board of Governors for Higher Education, State of Rhode Island and Providence Plantations - Providence RI
International Classification:
C40B 40/04 C07D 417/04
US Classification:
506 15, 548201
Abstract:
This invention provides a novel method for synthesizing an ensemble of peptides that allows for the generation of an unlimited number of antibiotic compounds. More specifically, the method comprises utilizes synthetic heterocyclic amino acids containing thaizole and/or oxazole as building blocks in a solid phase combinatorial synthesis to yield natural and unnatural antibiotic compounds.
This invention provides a novel method for synthesizing an ensemble of peptides that allows for the generation of an unlimited number of antibiotic compounds. More specifically, the method comprises utilizes synthetic heterocyclic amino acids containing thaizole and/or oxazole as building blocks in a solid phase combinatorial synthesis to yield natural and unnatural antibiotic compounds.
Name / Title
Company / Classification
Phones & Addresses
Lenore Martin Associate Professor College Of Environmental And Life Sciences-cmb
University of Rhode Island Colleges, Universities, and Professional Scho...
University of Rhode Island - Kingston, RI USA since 2002
Associate Professor
University of Rhode Island Jun 1994 - May 2002
Assistant Professor
The Rockefeller University 1989 - 1994
Research Associate
UCLA 1983 - 1989
Graduate Student
Education:
University of California, Los Angeles 1983 - 1989
PhD, Chemistry & Biochemistry
Northwestern University 1979 - 1983
BA, Chemistry & Biochemistry
Skills:
Biochemistry Protein Chemistry Life Sciences Hplc Biotechnology Chemistry Fluorescence Science Organic Chemistry Molecular Biology Nmr Analytical Chemistry Cell Dna Bioinformatics Protein Purification Mass Spectrometry Cell Culture Peptides Peptide Synthesis Uv/Vis Lifesciences Chromatography Structural Biology Immunology High Performance Liquid Chromatography Quality Control Cancer Cell Biology Informatics Protein Expression Western Blotting Molecular Modeling Laboratory Drug Metabolism Drug Discovery Spectroscopy Biology Fluorescence Spectroscopy Purification Microscopy Medicinal Chemistry Sds Page Pcr Elisa Biophysics Nuclear Magnetic Resonance Uv/Vis Spectroscopy