Richard L. Dunn - Birmingham AL John W. Gibson - Kingsport TN Carlton A. Eddy - San Antonio TX Leonard E. Laufe - San Antonio TX
Assignee:
Southern Research Institute - Birmingham AL Texas Health Science Center - San Antonio TX
International Classification:
A61L 1700
US Classification:
1283355
Abstract:
The controlled first-order release of either an antithrombotic or thrombolytic agent from a sutures at an anastomosis site is disclosed which prevents postoperative thrombosis and improves vascular patency in animals. A suitable polymer, such as polycaprolactone, is blended with prostacyclin or analogues of prostacyclin to form the suture material.