Central Indiana OrthopedicsCentral Indiana Orthopedics Center 2610 Enterprise Dr, Anderson, IN 46013 7656834400 (phone), 7656427903 (fax)
Education:
Medical School Baylor College of Medicine Graduated: 1998
Procedures:
Carpal Tunnel Decompression Lower Arm/Elbow/Wrist Fractures and Dislocations Occupational Therapy Evaluation Shoulder Surgery Arthrocentesis Hip/Femur Fractures and Dislocations
Conditions:
Fractures, Dislocations, Derangement, and Sprains Internal Derangement of Knee Cartilage Intervertebral Disc Degeneration Osteoarthritis Rotator Cuff Syndrome and Allied Disorders
Languages:
English
Description:
Dr. Chen graduated from the Baylor College of Medicine in 1998. He works in Anderson, IN and specializes in Orthopaedic Surgery and Hand Surgery. Dr. Chen is affiliated with Saint Vincent Anderson Center.
Central Indiana Orthopedics 13914 Southeastern Pkwy STE 304, Fishers, IN 46037 3177734301 (phone), 7656083659 (fax)
Languages:
English
Description:
Dr. Chen works in Fishers, IN and specializes in Orthopaedic Surgery and Hand Surgery. Dr. Chen is affiliated with Community Hospital North, Community Hospital Of Anderson, IU Health Ball Memorial Hospital and St Vincent Anderson Regional Hospital.
The invention provides modified recombinant nucleic acid sequences (preferably DNA) and methods for increasing the mRNA levels and protein expression of malarial surface protein MSP-1 which is known to be difficult to express in cell culture systems, mammalian cell culture systems, or in transgenic animals. The preferred protein candidates for expression using the recombinant techniques of the invention are MSP-1 proteins expressed from DNA coding sequences comprising reduced overall AT content or AT rich regions and/or mRNA instability motifs and/or rare codons relative to the native MSP-1 gene.
Modified Nucleic Acid Sequences And Methods For Increasing Mrna Levels And Protein Expression In Cell Systems
Li How Chen - Acton MA, US Harry Meade - Newton MA, US
Assignee:
GTC Biotherapeutics, Inc. - Framingham MA
International Classification:
C12P 21/00 A01K 61/00
US Classification:
800 7, 800 13, 530350, 536 237, 536 241
Abstract:
The invention provides modified recombinant nucleic acid sequences (preferably DNA) and methods for increasing the mRNA levels and protein expression of proteins which are known to be, or are likely to be, difficult to express in cell culture systems, mammalian cell culture systems, or in transgenic animals. The preferred “difficult” protein candidates for expression using the recombinant techniques of the invention are those proteins derived from heterologous cells preferably those of lower organisms such as parasites, bacteria, and virus, having DNA coding sequences comprising high overall AT content or AT rich regions and/or mRNA instability motifs and/or rare codons relative to the recombinant expression system to be used.
Merozoite Surface Protein 1 Lacking Glycosylation Sites
The invention provides modified recombinant nucleic acid sequences (preferably DNA) and methods for increasing the mRNA levels and protein expression of malarial surface protein MSP-1 which is known to be difficult to express in cell culture systems, mammalian cell culture systems, or in transgenic animals. The preferred protein candidates for expression using the recombinant techniques of the invention are MSP-1 proteins expressed from DNA coding sequences comprising reduced overall AT content or AT rich regions and/or mRNA instability motifs and/or rare codons relative to the native MSP-1 gene.
Modified Nucleic Acid Sequences And Methods For Increasing Mrna Levels And Protein Expression In Cell Systems
Li How Chen - Acton MA, US Harry Meade - Newton MA, US
Assignee:
GTC Biotherapeutics, Inc. - Framingham MA
International Classification:
C12P 21/00 A01K 67/00
US Classification:
800 7, 800 13, 530350, 536 237, 536 241
Abstract:
The invention provides modified recombinant nucleic acid sequences (preferably DNA) and methods for increasing the mRNA levels and protein expression of proteins which are known to be, or are likely to be, difficult to express in cell culture systems, mammalian cell culture systems, or in transgenic animals. The preferred “difficult” protein candidates for expression using the recombinant techniques of the invention are those proteins derived from heterologous cells preferably those of lower organisms such as parasites, bacteria, and virus, having DNA coding sequences comprising high overall AT content or AT rich regions and/or mRNA instability motifs and/or rare codons relative to the recombinant expression system to be used.
Method For Managing And Controlling Stability In Business Activity Monitoring And Management Systems
Bala Ramachandran - Harrison NY, US Li Chen - Palo Alto CA, US
Assignee:
International Business Machines Corporation - Armonk NY
International Classification:
G06F 17/30
US Classification:
705 728
Abstract:
A stabilization methodology and system component in Business Activity Monitoring and Management systems. This enables firms to use Business Activity Management (BAM) systems to manage business activity by only responding to monitored data when the overall business performance can be improved. This enables firms to identify appropriate tradeoffs between potentially conflicting objectives while meeting business objectives. Information from BAM systems are analyzed based on models of the business process and different information filter criteria are assessed for their impact on business performance indicators. Based on this, a filter criterion is chosen which is executed by an information filter. The outputs from the information filter are used as the basis for deciding the inputs for business process execution.
Reduced Stiction Mems Device With Exposed Silicon Carbide
Li Chen - Arlington MA, US Christine H. Tsau - Arlington MA, US Thomas Kieran Nunan - Carlisle MA, US Kuang L. Yang - Newton MA, US
Assignee:
Analog Devices, Inc. - Norwood MA
International Classification:
H01L 21/00
US Classification:
438 53, 257414
Abstract:
A MEMS device has a first member that is movable relative to a second member. At least one of the first member and the second member has exposed silicon carbide with a water contact angle of greater than about 70 degrees.
Method Of Fabricating A Dual Single-Crystal Backplate Microphone
A dual backplate MEMS microphone system including a flexible diaphragm sandwiched between two single-crystal silicon backplates may be formed by fabricating each backplate in a separate wafer, and then transferring one backplate from its wafer to the other wafer, to form two separate capacitors with the diaphragm.
Novel Modified Msp-1 Nucleic Acid Sequences And Methods For Increasing Mrna Levels And Protein Expression In Cell Systems
The invention provides modified recombinant nucleic acid sequences (preferably DNA) and methods for increasing the mRNA levels and protein expression of malarial surface protein MSP-1 which is known to be difficult to express in cell culture systems, mammalian cell culture systems, or in transgenic animals. The preferred protein candidates for expression using the recombinant techniques of the invention are MSP-1 proteins expressed from DNA coding sequences comprising reduced overall AT content or AT rich regions and/or mRNA instability motifs and/or rare codons relative to the native MSP-1 gene.
Jul 2010 to Sep 2013 Project coordinator, Corporate DevelopmentWatsons Asia, an A.S. Watsons Group company
Jan 2009 to Jun 2010 Buyer assistant, Merchandise Department
Education:
Northeastern University Boston, MA 2014 to 2015 Master of Science in Project ManagementChinese Culture University Jan 2008 Bachelor of Tourism Management
Skills:
Computer: MS Project, Microsoft Office, Adobe Photoshop, Photo Impact
Fudan University 1993 to 1997 BS in Genetics and Genetic EngineeringLehman College New York, NY Master of Science in Geographic Information System
Skills:
General computer knowledge - Microsoft Office, Photoshop, Python, RDBMS, etc. GIS-related software/tools - ESRI ArcGIS 10 or higher, WebGIS, GeoDa, QGIS, SaTScan, IDRISI, Spatial database (ArcSDE, Microsoft SQL server), Google Earth, Trimble GPS, etc. Problem solving - Resolves in-depth queries in a methodical manner independently to find appropriate resolutions with high level of quality and efficiency. Team Player - Enjoys sharing knowledge and encouraging development of others to achieve specific team goals. Planning and organizing - Refined planning and organizational skills that balance work, team support and responsibilities in a timely and professional manner. Communication - Deals with people at all levels via meeting, telephone and email, to ensure successful communication via actively listening and probing questions. Other Valid NYS driver license, Permanent residency of USA
CTIC CAPITAL Palo Alto, CA Sep 2014 to Dec 2014 Business AnalystNew York University NY Sep 2012 to Dec 2014 Project experienceHigh temperature metal lab,SKKU Suwon, South Korea Sep 2008 to Jun 2010 Research AssistantNews Agency of Materials School Wuhan, China Aug 2006 to Apr 2008 Intership
Education:
New York University New York, NY 2012 to 2014 Master in Finance and RiskSungkyunkwan University (SKKU) Suwon, South Korea 2010 to 2012 Master in Advanced Materials Science and EngineeringWuhan University of Technology Wuhan, China 2008 to 2010 BS in Materials
Skills:
R, SQL, STATA,Python, MS Excel, M.S. Office software,Origin Lab
CTIC Capital Palo Alto, CA Sep 2014 to Dec 2014 Business AnalystNew York University New York, NY Sep 2012 to Dec 2014 Academic ProjectsHTM Lab of SungKyunKwan University Suwon, South Korea Sep 2008 to Jun 2010 Research Assistant
Education:
New York University New York, NY 2012 to 2014 Master of Science in Finance EngineeringSungkyunkwan University Sep 2008 to Jun 2010 Master of Science in Advanced Material Science and EngineeringWuhan University of Technology Wuhan, CN Sep 2004 to Jun 2008 Bachelor of Science in Materials Science and Engineering
Center for Clinical Investigation, Brigham and Women's Hospital
Jul 2011 to 2000 Senior Clinical Research CoordinatorPain Research, Brigham and Women's Hospital Chestnut Hill, MA Nov 2007 to Jul 2011 Senior Clinical Research CoordinatorBarrett Lab, Boston College Chestnut Hill, MA Sep 2005 to May 2007 Undergraduate Faculty Research Fellow
Education:
Harvard University Extension School Cambridge, MA 2010 to 2013 Continuing Education in Biological SciencesNortheastern University College of Professional Studies Boston, MA 2010 to 2010 Continuing Education in Biological SciencesBoston College Chestnut Hill, MA Sep 2003 to May 2007 Bachelor of Arts in Psychology
Skills:
Computer: Extensive knowledge of Microsoft Word, Excel, Access, Outlook, PowerPoint, Adobe Photoshop, EndNote, SPSS, Teamsite Interwoven, REDCap Languages: Conversant in Cantonese Chinese
ChangZhou TCM Hospital, Department of Cardiovascular Changzhou, CN Jun 2013 to Jun 2014 InternAsian Community Development Corporation Boston, MA Jun 2012 to Dec 2012 InternNortheastern University Boston, MA May 2011 to May 2011 Volunteer Guide of Orientation
Education:
Northeastern University Boston, MA 2014 Master of Science in Regulatory affairsNortheastern University Boston, MA 2012 Bachelor of Science in Leadership, GPA 3.85
Skills:
1 year experience as a assistant of clinical trial in Department of Cardiovascular Strong knowledge of medical device regulation for example, 510 (K), IDE, and PMA. Strong knowledge of Investigational New Drug Application (IND), New Drug Application (NDA), Abbreviated New Drug Application (ANDA), Good Manufacturing Practices (cGMPs), Good Clinical Practices (GCP), Quality System Regulations (QSR), Federal Food, Drug, and Cosmetic Act of 1938 (FDCA), and ICH guidelines Strong knowledge of FDA regulations and CFDA regulations Solid knowledge of European, Canadian, and Australian Medical device regulations Proficiency in MS Office Applications (Microsoft Word, Excel and PowerPoint) Strong oral and written communication skill Excellent negotiation, and organization skill Verbal and written fluency in Mandarin and English
Name / Title
Company / Classification
Phones & Addresses
Li Yu Chen
Chous Consolidated Enterprise Real Estate Agents and Managers
4203 162Nd St, Flushing, NY 11358
Li Qin Chen Manager
Prudential Douglas Elliman Re Automotive Exhaust System Repair Shops
21545 Northern Blvd, Flushing, NY 11361
Li Chen Vice President
EIC Solutions USA Tour Operators
1511 3Rd Ave, Seattle, WA 98101
Li H. Chen President
Ching Chang Produce Co Whol Fruits/Vegetables
123 Newmarket Sq, Boston, MA 02118 6174642060
Li Chen Owner
Empire Chinese Restaurant Eating Place
321 Elwood Ave, Hawthorne, NY 10532 9147416210
Li Chen Owner
New Kings Food Restaurant Eating Place
127 Malcolm X Blvd, Brooklyn, NY 11221 7189197176
Li Rong Chen President
GOLD BOWL, INC Eating Place
22 Ashby State Rd, Fitchburg, MA 01420 749 Central St, Leominster, MA 01453
Li Hwa Chen Director
Hua Shing Inc Education Management
1 Griffin Way, Chelsea, MA 02150 66 Lochland St, Milton, MA 02186 6178840111
Toronto, CanadaSoftware Engineer at STMicroelectronics (Genesis) Past: Software Engineer at Blue Streak Electronics, Electronic Developer at Mandolyn Electronics...
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Li Chen
Work:
Shenzhen Capital Group (2011)
Education:
University of Pennsylvania - Finance, University of Chicago - International Relations
Li Chen
Education:
The Hong Kong Polytechnic University - Multimedia & Entertainment Technology, Huaqiao University - Industrial Design