Liang Zhai

US Patent:

20220304712, Sep 29, 2022

Filed:

Mar 23, 2022

Appl. No.:

17/702633

Inventors:

- Tokyo, JP
Liang ZHAI - Belmont CA, US
James D. MAZZONE - San Jose CA, US
Desmond CHEUNG - San Jose CA, US
Jaime MERINO - Mountain View CA, US
Eric Dailey - San Jose CA, US
Lewis J. Thomas - La Paz, MX

International Classification:

A61B 17/22
A61B 18/14
A61N 7/02

Abstract:

Described herein are acoustic-based tissue treatment systems, apparatuses, and methods for use therewith. Certain such apparatuses comprise a catheter sized and shaped for delivery through a radial artery including a catheter shaft having distal and proximal ends, a plurality of lumens extending longitudinally through the catheter shaft between the distal and proximal ends thereof, and an ultrasound transducer distally positioned relative to the distal end of the catheter shaft. A balloon may surround the ultrasound transducer and at least one of the plurality of lumens may be configured to provide a cooling fluid to the balloon at a pressure and flow rate sufficient to protect non-target tissue in the blood vessel wall from thermal injury. In certain embodiments, the apparatus also includes a single electrical cable extending through one of the lumens and including first conductor(s) coupled to the first electrode of the ultrasound transducer, and second conductor(s) coupled to the second electrode of the ultrasound transducer. The single electrical cable may be configured to deliver sufficient electrical energy during sonication to the transducer such that the transducer thermally induces modulation of neural fibers surrounding the blood vessel sufficient to improve a measurable physiological parameter corresponding to a diagnosed condition of the patient.

US Patent:

20230000468, Jan 5, 2023

Filed:

Sep 14, 2022

Appl. No.:

17/931928

Inventors:

- Malvern PA, US
Liang Zhai - Castro Valley CA, US

International Classification:

A61B 8/08
A61B 8/06

Abstract:

Color Doppler imaging with line artifact reduction is provided in multi-beam scanning. Doppler estimates representing the same spatial location but calculated from spatially distinctive transmit beam groups are combined through weighted linear interpolation. Methods of calculating the linear interpolation weights are provided based on geometric relationships and optimization functions. Complete overlapping and superposition among receive beams in the interpolation region are not required. Partial interpolation among the receive beams, where only the estimates of the outer receive scan lines may overlap and be interpolated while estimates for scan lines closer to the transmit scan line are not interpolated, allowing for more rapid frame rate.

US Patent:

20180325492, Nov 15, 2018

Filed:

Jul 25, 2018

Appl. No.:

16/044885

Inventors:

- Malvern PA, US
Liang Zhai - Castro Valley CA, US

International Classification:

A61B 8/08
A61B 8/06

Abstract:

Color Doppler imaging with line artifact reduction is provided in multi-beam scanning. Doppler estimates representing the same spatial location but calculated from spatially distinctive transmit beam groups are combined through weighted linear interpolation. Methods of calculating the linear interpolation weights are provided based on geometric relationships and optimization functions. Complete overlapping and superposition among receive beams in the interpolation region are not required. Partial interpolation among the receive beams, where only the estimates of the outer receive scan lines may overlap and be interpolated while estimates for scan lines closer to the transmit scan line are not interpolated, allowing for more rapid frame rate.

US Patent:

20180153514, Jun 7, 2018

Filed:

Dec 1, 2016

Appl. No.:

15/366286

Inventors:

Liang Zhai - Castro Valley CA, US
Wilko Wilkening - Mountain View CA, US

International Classification:

A61B 8/00
A61B 5/024
A61B 5/00
A61B 5/0245
A61B 8/08

Abstract:

A heart rate monitor provides a pulse or heartbeat, but without the on-going or continuous phase signal of ECG and/or with a delay relative to the actual heartbeat. For phase determination in echocardiography, the heartbeat from the heart rate monitor is used to assist in identification of phase from acquired ultrasound data. Rather than relying on just ECG or just image processing, the worn or handheld heart rate monitor is used to simplify the image process-based identification of phase.

US Patent:

20180028154, Feb 1, 2018

Filed:

Jul 29, 2016

Appl. No.:

15/224451

Inventors:

- Malvern PA, US
Liang Zhai - Castro Valley CA, US

International Classification:

A61B 8/08
A61B 8/00
A61B 8/14

Abstract:

Line artifact reduction is provided in multi-beam scanning for Doppler imaging. An analytic solution uses estimated velocities for collocated receive scan lines from different transmit beams to reduce or remove the biases caused by multi-beam receive. For each location, a line or curve is fit to the estimated velocities as a function of distance of the transmit scan lines to the location. The velocity at an intercept of this line with the distance of zero (intercept with the origin) indicates the unbiased velocity. This approach allows a solution even where all of the velocity estimates have a bias with the same sign, such as due to the location being on a same side of the different transmit scan lines.

US Patent:

20160287208, Oct 6, 2016

Filed:

Mar 30, 2015

Appl. No.:

14/673274

Inventors:

- Malvern PA, US
Liang Zhai - Castro Valley CA, US

International Classification:

A61B 8/02
A61B 5/00
A61B 8/08
A61B 8/00
A61B 5/0456

Abstract:

Guidance is provided in stress echocardiography. The recovery time after cessation of the stress is predicted using patient-specific information. The prediction may assist the user in acquiring images of the heart for stress echocardiography during the patient-relevant period, avoid unnecessary rush, and/or avoid acquisition of less useful images.

US Patent:

20150245818, Sep 3, 2015

Filed:

Mar 3, 2014

Appl. No.:

14/195715

Inventors:

- Malvern PA, US
Liang Zhai - Castro Valley CA, US

Assignee:

SIEMENS MEDICAL SOLUTIONS USA, INC. - Malvern PA

International Classification:

A61B 8/08
A61B 8/06

Abstract:

Color Doppler imaging with line artifact reduction is provided in multi-beam scanning. Doppler estimates representing the same spatial location but calculated from spatially distinctive transmit beam groups are combined through weighted linear interpolation. Methods of calculating the linear interpolation weights are provided based on geometric relationships and optimization functions. Complete overlapping and superposition among receive beams in the interpolation region are not required. Partial interpolation among the receive beams, where only the estimates of the outer receive scan lines may overlap and be interpolated while estimates for scan lines closer to the transmit scan line are not interpolated, allowing for more rapid frame rate.