Lily Yeh Lin

US Patent:

6566046, May 20, 2003

Filed:

Dec 7, 2000

Appl. No.:

09/732174

Inventors:

Lily Lin - Berkeley CA
Laurence Corash - San Francisco CA
Marc Payrat - Nivelles, BE

Assignee:

Baxter International Inc. - Deerfield IL
Cerus Corporation - Concord CA

International Classification:

A01N 102

US Classification:

435 2, 604 4, 604 20

Abstract:

Synthetic media formulations are disclosed for use with blood preparations intended for in vivo use, including synthetic media formulations to be employed in conjunction with the photodecontamination of platelets.

US Patent:

6866992, Mar 15, 2005

Filed:

Apr 14, 2003

Appl. No.:

10/413110

Inventors:

Lily Lin - Berkeley CA, US
Laurence Corash - San Francisco CA, US
Jean Marc Payrat - Nivelles, BE

Assignee:

Baxter International Inc. - Deerfield IL
Cerus Corporation - Concord CA

International Classification:

A01N001/02

US Classification:

435 2, 604 4, 604 20

Abstract:

Synthetic platelet storage media is disclosed for use with blood preparations intended for in vivo use. The synthetic platelet storage media is prepared by providing sodium chloride, sodium citrate, sodium acetate and sodium phosphate, and formulating in water 45-120 mM sodium chloride, 5-15 mM sodium citrate, 20-40 mM sodium acetate and 20-30 mM sodium phosphate.

US Patent:

56208529, Apr 15, 1997

Filed:

Oct 31, 1994

Appl. No.:

8/332616

Inventors:

Lily Lin - Berkeley CA
George Cimino - Richmond CA
Yu S. Zhu - Richmond CA

Assignee:

HRI Research, Inc. - Concord CA

International Classification:

C12Q 168
C12P 1934

US Classification:

435 6

Abstract:

The present invention provides a much simplified method for the preparation of nucleic acid samples. This method provides many advantages over prior sample preparation methods in terms of greater sensitivity, reliability and ease of use. Importantly, the present invention provides a method in which nucleic acid samples may be prepared so as to conserve reagents and time. The samples so prepared are readily amplifiable and may be used for other purposes as well.

US Patent:

59087420, Jun 1, 1999

Filed:

Aug 5, 1996

Appl. No.:

8/692444

Inventors:

Lily Lin - Berkeley CA
Laurence Corash - San Francisco CA
Jean Marc Payrat - Nivelles, BE

Assignee:

Cerus Corporation - Concord CA

International Classification:

A01N 102

US Classification:

435 2

Abstract:

Synthetic media formulations are disclosed for use with blood preparations intended for in vivo use, including essentially magnesium free synthetic media formulations to be employed in conjunction with the photodecontamination of platelets.

US Patent:

56186622, Apr 8, 1997

Filed:

Jan 21, 1994

Appl. No.:

8/184016

Inventors:

Lily Lin - Berkeley CA
Laurence Corash - San Francisco CA

Assignee:

Cerus Corporation - Concord CA

International Classification:

A01N 102
C12N 1300
A61K 3514

US Classification:

435 2

Abstract:

Intravenous administration of 8-methoxypsoralen is disclosed, and more specifically intravenous administration of 8-methoxypsoralen-blood preparations, including platelets. Random donor platelet bags are treated, stored and pooled prior to transfusion.

US Patent:

57099910, Jan 20, 1998

Filed:

Jun 7, 1995

Appl. No.:

8/480013

Inventors:

Lily Lin - Berkeley CA
Laurence Corash - San Francisco CA
John Tessman - San Leandro CA
George D. Cimino - Lafayette CA
Stephen T. Isaacs - Orinda CA

Assignee:

Cerus Corporation - Concord CA

International Classification:

A01N 102
A61M 3500

US Classification:

435 2

Abstract:

Methods are disclosed for photodecontamination to inactivate microorganisms in platelet preparations and for removal of psoralen after photodecontamination. Removal is achieved by contacting the psoralen with a psoralen-binding polymer.

US Patent:

56541791, Aug 5, 1997

Filed:

Oct 3, 1994

Appl. No.:

8/317220

Inventors:

Lily Lin - Berkeley CA

Assignee:

HRI Research, Inc. - Concord CA

International Classification:

C12P 1934
C07H 2102

US Classification:

435 912

Abstract:

The present invention provides an improved method for the preparation of ribonucleic acid (RNA) samples. This method utilizes heat and guanidinium thiocyanate treatment of samples followed by alcohol precipitation and centrifugation to prepare RNA samples with a high degree of sensitivity, reliability, and ease of use. Importantly, the prevent invention provides a method in which RNA samples may be prepared so as to conserve RNA preservation and precipitation reagents and time. The samples so prepared are readily amplifiable and may be used for other purposes as well.

US Patent:

59653493, Oct 12, 1999

Filed:

Mar 17, 1997

Appl. No.:

8/819379

Inventors:

Lily Lin - Berkeley CA
Laurence Corash - San Francisco CA

Assignee:

Cerus Corporation - Concord CA

International Classification:

A01N 102

US Classification:

435 2

Abstract:

Methods of photodecontamination are described which employ phosphate buffered aqueous solutions. Blood products comprising plasma are diluted with these solutions and treated with psoralen.