Lin Song Li

US Patent:

6508959, Jan 21, 2003

Filed:

May 29, 2001

Appl. No.:

09/867843

Inventors:

Lin Song Li - Los Alamos NM
Quanxi Jia - Los Alamos NM

Assignee:

The Regents of the University of California - Los Alamos NM

International Classification:

H01B 108

US Classification:

252514, 2525181, 2525212, 2525213, 106 115, 106 121, 106 128, 106 688, 4231795, 423594, 4271265, 427380, 428446, 428688, 501 53

Abstract:

A process is provided for the preparation of a metallic oxide composite including mixing an aqueous solution of a water-soluble metal compound and colloidal silica, depositing the mixture upon a substrate, heating the mixture-coated substrates at temperatures from about 150Â C. to about 300Â C. for time sufficient to form a metallic oxide film, and, removing the silica from the metallic oxide film whereby a porous metal oxide structure is formed.

US Patent:

6656390, Dec 2, 2003

Filed:

Jan 21, 2003

Appl. No.:

10/349297

Inventors:

Lin Song Li - Los Alamos NM
Quanxi Jia - Los Alamos NM

Assignee:

The Regents of the University of California - Los Alamos CA

International Classification:

H01B 108

US Classification:

2525181, 252514, 106 105, 4271261, 428688, 423 35

Abstract:

A process is provided for the preparation of a metallic oxide composite including mixing an aqueous solution of a water-soluble metal compound and colloidal silica, depositing the mixture upon a substrate, heating the mixture-coated substrates at temperatures from about 150Â C. to about 300Â C. for time sufficient to form a metallic oxide film, and, removing the silica from the metallic oxide film whereby a porous metal oxide structure is formed.

US Patent:

7160525, Jan 9, 2007

Filed:

Oct 14, 2004

Appl. No.:

10/965685

Inventors:

Xiaogang Peng - Fayetteville AR, US
Lin Song Li - Fayetteville AR, US
Nikhil Jana - Singapore, SG

Assignee:

The Board of Trustees of the University of Arkansas - Little Rock AR

International Classification:

C01G 5/00
C01G 7/00
C01G 51/00
C01G 55/00

US Classification:

423 1, 423 22, 423 23, 423 24, 423138, 423139

Abstract:

Nanoparticle compositions of noble metals, and methods of making them, are described. The nanoparticle compositions are made by reacting a salt or complex of a noble metal, such as Au, Ag, Cu or Pt, with a weak ligand, and a reducing agent, in a single liquid phase. The noble metal is typically provided as a halide or carboxylate. The ligand is preferably a fatty acid or aliphatic amine. The reducing agent is preferably a borohydride reagent, hydrazine, or a mixture thereof. Nanocrystals in the size range of 1 nm to 20 nm are produced, and can be made in substantially monodisperse form.

US Patent:

7541196, Jun 2, 2009

Filed:

Jun 29, 2005

Appl. No.:

11/172244

Inventors:

Jennifer S. Martinez - Santa Fe NM, US
Basil I. Swanson - Los Alamos NM, US
John E. Shively - Arcadia CA, US
Lin Li - Monrovia CA, US

Assignee:

Los Alamos National Security, LLC - Los Alamos NM

International Classification:

G01N 33/551

US Classification:

436524, 422 8205, 422 8211, 435 5, 435 6, 435 72, 4352872, 4352887, 436164, 436172, 436805

Abstract:

An assay element is described including recognition ligands adapted for binding to carcinoembryonic antigen (CEA) bound to a film on a single mode planar optical waveguide, the film from the group of a membrane, a polymerized bilayer membrane, and a self-assembled monolayer containing polyethylene glycol or polypropylene glycol groups therein and an assay process for detecting the presence of CEA is described including injecting a possible CEA-containing sample into a sensor cell including the assay element, maintaining the sample within the sensor cell for time sufficient for binding to occur between CEA present within the sample and the recognition ligands, injecting a solution including a reporter ligand into the sensor cell; and, interrogating the sample within the sensor cell with excitation light from the waveguide, the excitation light provided by an evanescent field of the single mode penetrating into the biological target-containing sample to a distance of less than about 200 nanometers from the waveguide thereby exciting any bound reporter ligand within a distance of less than about 200 nanometers from the waveguide and resulting in a detectable signal.

US Patent:

20040171175, Sep 2, 2004

Filed:

Feb 28, 2003

Appl. No.:

10/377515

Inventors:

Basil Swanson - Los Alamos NM, US
Clifford Unkefer - Los Alamos NM, US
Jurgen Schmidt - Los Alamos NM, US
Scott Reed - Tesuque NM, US
John Shively - Arcadia CA, US
Lin Li - Monrovia CA, US

International Classification:

G01N033/543

US Classification:

436/518000

Abstract:

A process is provided of conjugating a recognition element such as a biomolecule to a hydrophobic multifunctional linker molecule by incorporating a multifunctional linker molecule including one or more anchoring groups, a reporter group and a reactive site thereon into a membrane, and, reacting the membrane including the incorporated multifunctional linker molecule with a pre-selected recognition element to form a covalently bound recognition element-multifunctional linker molecule-membrane assembly. Also, a chemical assembly suitable for subsequent covalent attachment of a recognition element is provided such assembly including a multifunctional linker molecule including one or more anchoring groups, a reporter group, and a hydrophilic spacer terminated by a reactive group capable of subsequent covalent bonding, the one or more anchoring groups incorporated in a membrane.

US Patent:

20060057766, Mar 16, 2006

Filed:

Jul 8, 2003

Appl. No.:

10/615645

Inventors:

Quanxi Jia - Los Alamos NM, US
Lin Li - Fayetteville AR, US

International Classification:

H01L 21/00

US Classification:

438085000, 438104000, 438086000

Abstract:

A polymer assisted solution process for deposition of semiconductive thin films is presented. The process can be organic solvent-free. The process includes solutions of necessary metal precursors and soluble polymers. After a coating operation, the resultant coating is fired at high temperatures to yield optical quality metal oxide thin films that can be converted to semiconductive thin films.

US Patent:

20110217459, Sep 8, 2011

Filed:

Oct 16, 2007

Appl. No.:

11/974970

Inventors:

Basil I. Swanson - Los Alamos NM, US
Clifford J. Unkefer - Los Alamos NM, US
Jurgen G. Schmidt - Los Alamos NM, US
Scott M. Reed - Tesuque NM, US
John E. Shively - Arcadia CA, US
Lin Li - Monrovia CA, US

International Classification:

B05D 5/06

US Classification:

427157

Abstract:

A process is provided of conjugating a recognition element such as a biomolecule to a hydrophobic multifunctional linker molecule by incorporating a multifunctional linker molecule including one or more anchoring groups, a reporter group and a reactive site thereon into a membrane, and, reacting the membrane including the incorporated multifunctional linker molecule with a pre-selected recognition element to form a covalently bound recognition element-multifunctional linker molecule-membrane assembly. Also, a chemical assembly suitable for subsequent covalent attachment of a recognition element is provided such assembly including a multifunctional linker molecule including one or more anchoring groups, a reporter group, and a hydrophilic spacer terminated by a reactive group capable of subsequent covalent bonding, the one or more anchoring groups incorporated in a membrane.