Lin L Pan

US Patent:

20090155209, Jun 18, 2009

Filed:

May 2, 2008

Appl. No.:

12/114639

Inventors:

LAWRENCE M. BLATT - SAN FRANCISCO CA, US
LIN PAN - SUNNYVALE CA, US
SCOTT SEIWERT - PACIFICA CA, US
PIERRE MARTIN - RHEINFELDEN, CH
ANDREAS SCHUMACHER - EFRINGEN-KIRCHEN, DE
LEONID BEIGELMAN - SAN MATEO CA, US
JYANWEI LIU - SUNNYVALE CA, US
STEVEN W. ANDREWS - LONGMONT CO, US
KEVIN R. CONDROSKI - LAFAYETTE CO, US
YUTONG JIANG - LONGMONT CO, US
ROBERT J. KAUS - LONGMONT CO, US
APRIL L. KENNEDY - DENVER CO, US
TIMOTHY S. KERCHER - BOULDER CO, US
MICHAEL A. LYON - SUPERIOR CO, US
BIN WANG - LONGMONT CO, US

International Classification:

A61K 31/407
C07D 487/04
A61K 31/7056
A61K 31/427
A61K 38/21
A61P 31/12

US Classification:

424 855, 548428, 514411, 514 43, 514365, 424 857

Abstract:

The embodiments provide compounds of the general Formula I, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.