Roger D. Cone - Oregon City OR Kathleen G. Mountjoy - Portland OR Linda S. Robbins - Portland OR
Assignee:
Oregon Health Science University - Portland OR
International Classification:
C07K 14705 C12N 510
US Classification:
435325
Abstract:
The present invention relates to a mammalian melanocortin receptor. The invention is directed toward the isolation, characterization and pharmacological use of a mammalian melanocortin receptor (MC3-R). The invention specifically provides a particular melanocortin receptor, termed MC3-R, isolated as a complementary DNA copy of mRNA corresponding to the gene for this receptor in rats. Also provided is a eukaryotic recombinant expression construct capable of expressing a mammalian melanocortin receptor in cultures of transformed eukaryotic cells and such cultures of transformed eukaryotic cells that synthesize a mammalian melanocortin receptor. The invention also provides methods for screening in vitro agonists and antagonists of such a melanocortin receptor using preparations of receptor protein from such cultures of eukaryotic cells transformed with a recombinant expression construct.
Roger D. Cone - Oregon City OR Kathleen G. Mountjoy - Portland OR Linda S. Robbins - Portland OR
Assignee:
Oregon Health Sciences University - Portland OR
International Classification:
G01N 33567 G01N 3353 G01N 33574 G01N 3348
US Classification:
435 721
Abstract:
The present invention relates to a mammalian melanocortin receptor. The invention is directed toward the isolation, characterization and pharmacological use of a mammalian melanocortin receptor (MC3-R). The invention specifically provides a particular melanocortin receptor, termed MC3-R, isolated as a complementary DNA copy of mRNA corresponding to the gene for this receptor in rats. Also provided is a eukaryotic recombinant expression construct capable of expressing a mammalian melanocortin receptor in cultures of transformed eukaryotic cells and such cultures of transformed eukaryotic cells that synthesize a mammalian melanocortin receptor. The invention also provides methods for screening in vitro agonists and antagonists of such a melanocortin receptor using preparations of receptor protein from such cultures of eukaryotic cells transformed with a recombinant expression construct.
Nucleic Acids Encoding The .Gamma.-Msh Receptor Mc3-R
Roger D. Cone - Oregon City OR Kathleen G. Mountjoy - Portland OR Linda S. Robbins - Portland OR
Assignee:
State of Oregon - Portland OR
International Classification:
C07H 2104 C12N 1512
US Classification:
4352401
Abstract:
The present invention relates to a mammalian melanocortin receptor. The invention is directed toward the isolation, characterization and pharmacological use of a mammalian melanocortin receptor (MC3-R). The invention specifically provides a particular melanocortin receptor, termed MC3-R, isolated as a complementary DNA copy of mRNA corresponding to the gene for this receptor in rats. Also provided is a eukaryotic recombinant expression construct capable of expressing a mammalian melanocortin receptor in cultures of transformed eukaryotic cells and such cultures of transformed eukaryotic cells that synthesize a mammalian melanocortin receptor. The invention also provides methods for screening in vitro agonists and antagonists of such a melanocortin receptor using preparations of receptor protein from such cultures of eukaryotic cells transformed with a recombinant expression construct.
Niantic-Harristown High School Niantic IL 1964-1968
Community:
Sami Bloemer, Cinda Cindy, Ann Travis, Maryann Eastman, Claudia Beckham, Mary Byers, Jane Durflinger, Jeanna Glacken, Richard Nicolas, Linda Hupp, Sandy Livesey, David Frazee
Biography:
STILL LIVE IN DECATUR. WORK FOR MACON COUNTY CORONER. LOVE MY JOB. KIDS GROWN-(GO...
Aug 24, 2011 (Herald-Times - McClatchy-Tribune Information Services via COMTEX) -- Monroe County Clerk Linda Robbins is being stubborn. She's disregarding the will of the Legislature and the opinion of the Secretary of State's office by insisting that ...
She is survived by her father, Robert Lee Fuller; brother, Tony Fuller of Murfreesboro; sisters, Robbie Minchey of Lebanon, Linda Robbins of Lebanon and Cherrie Fuller of Mt. Juliet. Graveside service will be held at 2:00 pm on Saturday, August 13, ...
'ONE OF THE BEST': Linda Robbins of Spartanburg is singing the praises of the Gibbs Cancer Center. It is one of the best, she declares. My son went there, and they saved his life. He can really test your nerves when he is sick, but down there they ...
Crowd turns out for Chickasaw reunion; more north Mobile County news from Jo ...
11 at the home of Linda Robbins, 605 Vallier Court. For information, call Ramona Knight, 251-675-4008. Chickasaw Recreation Department is offering self-defense and karate classes for Young and Older on Tuesdays and Thursdays, 5:30-7 pm at McConnell ...
The complaint, filed by attorney Walter Skotynsky, asks for damages in excess of $35000. The case was assigned to Judge Linda Jennings. Robbins was indicted Feb. 2, 2010, by a Lucas County grand jury on two alternate counts of murder. ...