Linda A Wang

US Patent:

20110034485, Feb 10, 2011

Filed:

Apr 16, 2009

Appl. No.:

12/937405

Inventors:

Yuqiang Wang - Guangzhou, CN
Jie Jiang - Guangzhou, CN
Pei Yu - Guangzhou, CN
Yewei Sun - Guangzhou, CN
Linda Wang - Cupertino CA, US
Zaijun Zhang - Guangzhou, CN

International Classification:

A61K 31/505
C07D 239/30
A61P 25/00
A61P 9/00
A61P 27/02
A61P 29/00
A61P 35/00

US Classification:

514256, 544335

Abstract:

The present invention provides novel nitrones, their preparation and use. The novel compounds have the following formula: I The compounds of the present invention have strong antioxidative activity, and are thrombolytic. These compounds can be used to treat and/or prevent diseases caused by overproduction of free radicals and/or formation of thrombus.

US Patent:

20160150976, Jun 2, 2016

Filed:

Jun 25, 2014

Appl. No.:

14/900485

Inventors:

- Boston MA, US
Bernhard Zimmermann - Cambridge MA, US
Linda T. Wang - Newton MA, US
Patricia Hibberd - Lexington MA, US
Robert Cleveland - Newton Highlands MA, US
Jim Lewis - Brookline MA, US

Assignee:

The General Hospital Corporation - Boston MA

International Classification:

A61B 5/01
A61B 5/00

Abstract:

Exemplary of the present disclosure can include an apparatus for generating thermal imaging information of a biological structure(s), including detector arrangement(s) which can be configured to receive and detect light radiation(s), a determination arrangement(s) which can be configured to determine a position or an orientation of the detector arrangement(s) with respect to the biological structure(s) to generate data, and a computer arrangement configured to generate the thermal imaging information based on the radiation and the data when the detector arrangement(s) is moved. The thermal imaging information can include a 2-dimension temperature map(s) of a portion(s) of the biological structure(s). The thermal imaging information can include a 3-dimension temperature map(s) of a portion(s)