Ling Bin Chen

US Patent:

7604771, Oct 20, 2009

Filed:

May 5, 2006

Appl. No.:

11/418957

Inventors:

Sun-Ju Song - Orland Park IL, US
Tae H. Lee - Naperville IL, US
Ling Chen - Woodridge IL, US
Stephen E. Dorris - LaGrange Park IL, US
Uthamalingam Balachandran - Hinsdale IL, US

Assignee:

UChicago Argonne, LLC - Chicago IL

International Classification:

B28B 3/00
B01D 53/22

US Classification:

264674, 264676, 96 11

Abstract:

A thermal method of making a hydrogen permeable composition is disclosed. A mixture of metal oxide powder and ceramic oxide powder and optionally a pore former is formed and pressed to form an article. The article is dried at elevated temperatures and then sintered in a reducing atmosphere to provide a dense hydrogen permeable portion near the surface of the sintered mixture. The dense hydrogen permeable portion has a higher initial concentration of metal than the remainder of the sintered mixture and is present in the range of from about 20 to about 80 percent by volume of the dense hydrogen permeable portion.

US Patent:

7959716, Jun 14, 2011

Filed:

Sep 30, 2009

Appl. No.:

12/586978

Inventors:

Sun-Ju Song - Orland Park IL, US
Tae H. Lee - Naperville IL, US
Ling Chen - Woodridge IL, US
Stephen E. Dorris - LaGrange Park IL, US
Uthamalingam Balachandran - Hinsdale IL, US

Assignee:

UChicago Argonne, LLC - Chicago IL

International Classification:

B01D 53/22
C04B 35/64

US Classification:

96 11, 96 7, 95 55, 95 56, 429411, 502 4, 264 44, 264666, 264674, 264676, 264681

Abstract:

A hydrogen permeable membrane is disclosed. The membrane is prepared by forming a mixture of metal oxide powder and ceramic oxide powder and a pore former into an article. The article is dried at elevated temperatures and then sintered in a reducing atmosphere to provide a dense hydrogen permeable portion near the surface of the sintered mixture. The dense hydrogen permeable portion has a higher initial concentration of metal than the remainder of the sintered mixture and is present in the range of from about 20 to about 80 percent by volume of the dense hydrogen permeable portion.

US Patent:

8017733, Sep 13, 2011

Filed:

Jul 16, 2004

Appl. No.:

10/892830

Inventors:

KoChung Lin - Lexington MA, US
R. Blake Pepinsky - Arlington MA, US
Ling Ling Chen - Wellesley MA, US
Donna M. Hess - Waltham MA, US
Edward Y. Lin - Somerville MA, US
Russell C. Petter - Stow MA, US
Darren P. Baker - Hingham MA, US

Assignee:

Biogen Idec MA Inc. - Cambridge MA

International Classification:

C07K 17/08
C07K 14/565
C11D 3/38
C08G 59/00
C08G 59/14
C11D 3/386

US Classification:

530351, 435 6951, 436 86, 510320, 525525, 525526

Abstract:

The invention relates to novel polyalkylene glycol compounds and methods of using them. In particular, compounds comprising a novel polyethylene glycol conjugate are used alone, or in combination with antiviral agents to treat a viral infection, such as chronic hepatitis C.

US Patent:

8524660, Sep 3, 2013

Filed:

Sep 12, 2011

Appl. No.:

13/230080

Inventors:

KoChung Lin - Lexington MA, US
R. Blake Pepinsky - Arlington MA, US
Ling Ling Chen - Wellesley MA, US
Donna M. Hess - Waltham MA, US
Edward Y. Lin - Somerville MA, US
Russell C. Petter - Stow MA, US
Darren P. Baker - Hingham MA, US

Assignee:

Biogen Idec MA Inc. - Cambridge MA

International Classification:

A61K 47/48
C08G 65/329
A61K 38/00
C07K 17/08
A61K 31/00
A61K 38/21
C07K 14/565
C12N 15/22

US Classification:

514 43, 514 179, 514 37, 514 23, 514 11, 514 1, 435 6951, 436 86, 510320, 525525, 525526, 530351

Abstract:

The invention relates to novel polyalkylene glycol compounds and methods of using them. In particular, compounds comprising a novel polyethylene glycol conjugate are used alone, or in combination with antiviral agents to treat a viral infection, such as chronic hepatitis C.

US Patent:

20070044662, Mar 1, 2007

Filed:

May 5, 2006

Appl. No.:

11/418954

Inventors:

Sun-Ju Song - Orland Park IL, US
Tae Lee - Naperville IL, US
Ling Chen - Woodridge IL, US
Stephen Dorris - LaGrange Park IL, US
Uthamalingam Balachandran - Hinsdale IL, US

Assignee:

The University of Chicago - Chicago IL

International Classification:

B01D 53/22

US Classification:

096004000

Abstract:

A method of making a hydrogen permeable in which a colloid suspension of metal powder and ceramic oxide powder dispersed in an organic carrier is contacted with a porous ceramic substrate to deposit a thin film of the colloid suspension on the substrate. The film is then dried and sintered to provide a two part membrane adhered to the porous ceramic substrate. The two part membrane has a metal powder part of one or more of Ni, Pd, Pd alloys, Nb, Ta, Zr, V or mixtures thereof, and an oxide part of one or more of yttria stabilized zirconia, shrinkable alumina, suitably doped cerates, titanates, zirconates of barium or strotium or mixtures thereof, wherein the metal powder part is present in the range of from about 20 to about 80 percent by volume of the two-part membrane.

US Patent:

20070044663, Mar 1, 2007

Filed:

May 5, 2006

Appl. No.:

11/418955

Inventors:

Sun-Ju Song - Orland Park IL, US
Tae Lee - Naperville IL, US
Ling Chen - Woodridge IL, US
Stephen Dorris - LaGrange Park IL, US
Uthamalingam Balachandran - Hinsdale IL, US

Assignee:

The University of Chicago - Chicago IL

International Classification:

B01D 53/22

US Classification:

096011000

Abstract:

A hydrogen permeable composition having a porous ceramic substrate, and a two part membrane adhered thereto. The two part membrane has a metal powder part and a ceramic oxide part, with the metal powder part being Ni, Pd, Pd alloys, Nb, Ta, Zr, V or mixtures thereof. The oxide part is yttria stabilized zirconia, shrinkable alumina, suitably doped cerates, titanate, zirconates of barium or strontium or mixtures thereof, and the hydrogen flux is at least 20 cmper minute-cmat 500 C. in a 100% hydrogen atmosphere. A paste method of forming the composition is disclosed. A method of extracting hydrogen from a gas is also disclosed.

US Patent:

62076485, Mar 27, 2001

Filed:

Jul 17, 1998

Appl. No.:

9/118179

Inventors:

David J. Waxman - Newton MA
Ling Chen - Blue Bell PA

Assignee:

Trustees of Boston University - Boston MA

International Classification:

A01N43/04
7
C12N15/00
15/63
7
C07H21/04

US Classification:

514 44

Abstract:

Methods of killing neoplastic cells are provided. The invention relates to the use of NADPH-cytochrome P450 reductase (RED) gene transfer in combination with cytochrome P450 gene transfer to enhance the sensitivity of tumor cells to anti-cancer drugs that are activated by P450 enzymes. The use of bioreductive drugs that are activated by RED and/or cytochrome P450, in this paradigm, is also provided.

US Patent:

20170049904, Feb 23, 2017

Filed:

Aug 15, 2016

Appl. No.:

15/237064

Inventors:

- Cambridge MA, US
Blake PEPINSKY - Arlington MA, US
Ling Ling CHEN - Wellesley MA, US
Donna M. HESS - Waltham MA, US
Edward Y. LIN - Somerville MA, US
Russell C. PETTER - Stow MA, US
Darren P. BAKER - Hingham MA, US

Assignee:

BIOGEN MA INC. - Cambridge MA

International Classification:

A61K 47/48
A61K 38/21
A61K 9/00
A61K 45/06

Abstract:

The invention relates to novel polyalkylene glycol compounds and methods of using them. In particular, compounds comprising a novel polyethylene glycol conjugate are used alone, or in combination with antiviral agents to treat a viral infection, such as chronic hepatitis C.