Ling W Li

US Patent:

6653318, Nov 25, 2003

Filed:

Jul 21, 1999

Appl. No.:

09/358028

Inventors:

Yung-Chi Cheng - Woodbridge CT
Chung K. Chu - Athens GA
Ling Li - Hamden CT
Yongseok Chai - Athens GA

Assignee:

Yale University - New Haven CT
The University of Georgia Research Foundation, Inc. - Athens GA

International Classification:

A61K 31505

US Classification:

514274, 514256, 514269, 514272, 514467, 514461

Abstract:

The present invention relates to pyrimidine nucleoside compounds and their use to treat viral infections of Varicella Zoster virus and Epstein Barr Virus, as well as cancers which are complications of Epstein Barr virus.

US Patent:

7244717, Jul 17, 2007

Filed:

Aug 21, 2002

Appl. No.:

10/226799

Inventors:

Ling Li - Seattle WA, US
Alexander Gall - Woodinville WA, US
Richard Daifuku - Mercer Island WA, US

Assignee:

Koronis Pharmaceuticals, Incorporated - Redmond WA

International Classification:

A61K 31/70
C07H 19/067
C07H 19/09

US Classification:

514 50, 514 51, 536 2854, 536 274

Abstract:

The present invention relates to methods of treating viral disease using mutagenic nucleoside analogs. In particular, the invention provides 5-aldehydo-uracil nucleosides and derivatives thereof, and methods of administration thereof to increase the virus mutation rate in a virally infected cell.

US Patent:

7648967, Jan 19, 2010

Filed:

Feb 13, 2006

Appl. No.:

11/353489

Inventors:

Ling Li - Seattle WA, US
Alexander Gall - Woodinville WA, US
Richard Daifuku - Mercer Island WA, US

Assignee:

Koronis Pharmaceuticals, Incorporated - Redmond WA

International Classification:

A61K 31/70
C07H 19/167
C07H 19/173
C07H 19/20
C12P 19/40
C12P 19/30
C12P 19/34

US Classification:

514 45, 514 48, 435 88, 435 89, 435 9121, 536 2626, 536 267, 536 277

Abstract:

The present invention relates to methods of treating viral disease using mutagenic nucleoside analogs. In particular, the invention provides isoguanosine nucleosides and derivatives thereof as well a method of increasing the mutation rate of a virus such as bovine viral diarrhea virus (BVDV) and hepatitis C virus (HCV).

US Patent:

20040053891, Mar 18, 2004

Filed:

Sep 2, 2003

Appl. No.:

10/653538

Inventors:

Yung-Chi Cheng - Woodbridge CT, US
Chung Chu - Athens GA, US
Ling Li - Hamden CT, US

International Classification:

A61K031/675
A61K031/513

US Classification:

514/085000, 514/269000

Abstract:

The present invention relates to pyrimidine nucleoside compounds and their use to treat viral infections of Varicella Zoster Virus, Epstein Barr Virus and Kaposi's Sarcoma virus, also known as HV-8 and related complications of these viral infections. In another aspect of the present invention, the use of one or more nucleoside compound to increase the retention or half-life of 5-fluorouracil (FU) in patients is also described.

US Patent:

20080314519, Dec 25, 2008

Filed:

Jul 11, 2006

Appl. No.:

11/995043

Inventors:

Shabbir Attarwala - Simsbury CT, US
Rosa M. Davila - Sabana Grande PR, US
Benjamin Surowiecki - Cheshire CT, US
Stan Wojciak - New Britain CT, US
Ling Li - Glastonbury CT, US
Roger Grismala - Enfield CT, US

Assignee:

Henkel Corporation - Rocky Hill CT

International Classification:

C09J 4/04
C09J 5/00

US Classification:

1563318, 525295, 524560, 522116

Abstract:

This invention relates to cyanoacrylate-containing compositions that include, in addition to the cyanoacrylate component, a rubber toughening component, which is substantially clear and colorless and which is substantially free of release agents and anti-oxidants known to impair the fixture speeds and shelf life stability of cyanoacrylate compositions to which they are added. As a result, the inventive rubber cyanoacrylate adhesive compositions demonstrate improved properties, such as fixture speed, strength and shelf life under accelerated aging conditions.

US Patent:

20090093560, Apr 9, 2009

Filed:

Sep 17, 2008

Appl. No.:

12/283934

Inventors:

Paul Van Rheenen - Warminster PA, US
Eric G. Lundquist - North Wales PA, US
Brian H. Clare - Portland OR, US
Ling Li - Blue Bell PA, US

International Classification:

C08J 9/00
C08L 27/14
C08L 33/10
C08L 33/26

US Classification:

521134, 525199, 525227, 525218

Abstract:

A halogenated polymer containing a functionalized polymer and optionally a blowing agent.

US Patent:

20090298969, Dec 3, 2009

Filed:

Jun 18, 2009

Appl. No.:

12/487090

Inventors:

Shabbir Attarwala - Simsbury CT, US
Ling Li - Glastonbury CT, US
John J. Cocco - Vernon CT, US

Assignee:

Henkel Corporation - Rocky Hill CT

International Classification:

C08L 67/00

US Classification:

523201

Abstract:

The present invention provides a cyanoacrylate composition comprising a cyanoacrylate component; and a core shell rubber component having a particle size in the range of 3 nm to 1,000 nm dispersed in a curable (meth)acrylate matrix.

US Patent:

20100279968, Nov 4, 2010

Filed:

Dec 27, 2006

Appl. No.:

11/616622

Inventors:

Ling Li - Seattle WA, US
Alexander Gall - Woodinville WA, US
Richard Daifuku - Mercer Island WA, US

Assignee:

Koronis Pharmaceuticals, Inc. - Redmond WA

International Classification:

A61K 31/708
C12N 7/06
A61K 31/7072
A61P 31/16
A61P 31/14
A61P 31/20
C07H 19/06
C07H 19/16
A61P 31/18

US Classification:

514 45, 435238, 514 50, 536 2853, 536 277

Abstract:

The present invention relates to methods of treating viral disease using mutagenic nucleoside analogs.