Ling Ling Li

US Patent:

6887896, May 3, 2005

Filed:

Oct 29, 2003

Appl. No.:

10/696748

Inventors:

Richard L. Beard - Newport Beach CA, US
Tien T. Duong - Irvine CA, US
Janet A. Takeuchi - Anaheim CA, US
Ling Li - Irvine CA, US
Kwok Yin Tsang - Irvine CA, US
Xiaoxia Liu - Tustin CA, US
Jayasree Vasudevan - Anaheim CA, US
Liming Wang - Irvine CA, US
Santosh C. Sinha - Irvine CA, US
Haiqing Yuan - Irvine CA, US
Roshantha A. Chandraratna - Laguna Hills CA, US

Assignee:

Allergan, Inc. - Irvine CA

International Classification:

A61K031/35
A61K031/235
A61K031/19

US Classification:

514456, 514532, 514569, 560 56, 562466

Abstract:

Compounds of the formula where the variations have the meaning defined in the specification are capable of reducing serum glucose levels in diabetic mammals without the undesirable side effects of transiently increasing triglyceride levels and reducing serum thyroxine levels.

US Patent:

7226951, Jun 5, 2007

Filed:

Dec 16, 2004

Appl. No.:

11/014460

Inventors:

Jayasree Vasudevan - Anaheim CA, US
Liming Wang - Irvine CA, US
Xiaoxia Liu - Tustin CA, US
Kwok Yin Tsang - Irvine CA, US
Ling Li - Irvine CA, US
Janet A. Takeuchi - Anaheim CA, US
Thong Vu - Garden Grove CA, US
Richard Beard - Newport Beach CA, US
Smita Bhat - Irvine CA, US
Vidyasagar Vuligonda - Irvine CA, US
Roshantha A. Chandraratna - Laguna Hills CA, US

Assignee:

Allergan, Inc. - Irvine CA

International Classification:

A61K 31/135
C07C 62/00
C07C 69/52
C07C 211/16

US Classification:

514654, 562500, 564384

Abstract:

Compounds of formulas 1 through 17 provided in the specification specifically or selectively inhibit either the cytochrome P450RAI-1 enzyme or the cytochrome P450RAI-2 enzyme.

US Patent:

7468391, Dec 23, 2008

Filed:

Dec 13, 2004

Appl. No.:

11/010953

Inventors:

Jayasree Vasudevan - Anaheim CA, US
Rong Yang - Viejo CA, US
Liming Wang - Irvine CA, US
Xiaoxia Liu - Nashua NH, US
Ling Li - Irvine CA, US
Janet Takeuchi - Anaheim CA, US
Thong Vu - Garden Grove CA, US
Richard Beard - Newport Beach CA, US
Smita Bhat - Irvine CA, US
Roshantha A. Chandraratna - Laguna Hills CA, US

Assignee:

Allergan, Inc. - Irvine CA

International Classification:

A01N 31/00
A61K 9/00
A61K 31/415
A61K 9/20
A61K 9/48

US Classification:

514567, 424400, 424404

Abstract:

The invention provides methods for treating an individual having a retinoid responsive disorder. In one embodiment, a method involves administering to the individual an effective amount of a selective CYP26B inhibitor, the selective CYP26B inhibitor having at least 10-fold selectivity for CYP26B relative to CYP26A. In another embodiment, a method involves administering to the individual an effective amount of a selective CYP26A inhibitor, the selective CYP26A inhibitor having a chemical formula set forth in the specification. The invention further provides screening methods for identifying a selective CYP26A inhibitor or selective CYP26B inhibitor.

US Patent:

7638648, Dec 29, 2009

Filed:

Mar 23, 2007

Appl. No.:

11/728313

Inventors:

Jayasree Vasudevan - Anaheim CA, US
Liming Wang - Irvine CA, US
Xiaoxia Liu - Tustin CA, US
Kwok Yin Tsang - Irvine CA, US
Ling Li - Irvine CA, US
Janet A. Takeuchi - Anaheim CA, US
Thong Vu - Garden Grove CA, US
Richard Beard - Newport Beach CA, US
Smita Bhat - Irvine CA, US
Vidyasagar Vuligonda - Irvine CA, US
Roshantha A. Chandraratna - Laguna Hills CA, US

Assignee:

Allergan Inc. - Irvine CA

International Classification:

C07D 265/06
C07D 263/02
C07D 277/02
C07D 213/02
C07D 333/04
C07D 307/34
C07C 229/34

US Classification:

562433, 562442, 562452, 562488, 562492, 549332, 549398, 549405, 549408, 549429, 548146, 548206, 548215, 548240, 546329

Abstract:

Compounds of formulas 1 through 17 provided in the specification specifically or selectively inhibit either the cytochrome P450RAI-1 enzyme or the cytochrome P450RAI-2 enzyme.

US Patent:

7858539, Dec 28, 2010

Filed:

Apr 9, 2007

Appl. No.:

11/784711

Inventors:

Ling Li - Blue Bell PA, US
Shulong Li - Spartanburg SC, US
Jeffrey S. Lane - Moore SC, US

Assignee:

Milliken & Company - Spartanburg SC

International Classification:

B32B 27/04

US Classification:

442123, 811559

Abstract:

Provided herein are processes for topically applying an antimicrobial finish to a textile substrate, such as a yarn, a fabric, a composite, or an assembled article (for example, a garment). Specifically, the antimicrobial finish is based on hindered amine compounds that are applied in an aqueous bath (such as a commercial or home laundry setting), using the factors of pH and compound solubility to promote the formation of a durable antimicrobial halamine finish. Advantageously, the antimicrobial finish, which may be applied to fabrics made of any of a variety of fiber types and combinations of fiber types, has been found to be durable to repeated launderings.

US Patent:

7985795, Jul 26, 2011

Filed:

Sep 18, 2009

Appl. No.:

12/586266

Inventors:

Barrett Richard Bobsein - Sellersville PA, US
Melissa Merlau Johnson - Ambler PA, US
Joseph Joseph Rabasco - Allentown PA, US
Ling Li - Blue Bell PA, US

Assignee:

Rohm and Haas Company - Philadelphia PA

International Classification:

C08L 53/00
C08G 18/42

US Classification:

524505, 524500

Abstract:

A polymer composition with blocks of hydrophobes attached to or within the backbone of an associative thickener. The blocks are composed of two or more units of the same or different hydrophobes whereby the hydrophobe is reversibly switched between being hydrophilic and hydrophobic in nature. When the hydrophobe is rendered hydrophilic, the aqueous thickener is pourable and readily incorporated into aqueous polymer compositions. When this hydrophobe is rendered hydrophobic, the thickener performs its thickening function efficiently, especially in tinted systems. Switching is readily accomplished by adjusting the pH of the associative thickener composition and the aqueous polymer composition being thickened.

US Patent:

8080570, Dec 20, 2011

Filed:

May 1, 2009

Appl. No.:

12/433953

Inventors:

Janet A. Takeuchi - Anaheim CA, US
Ken Chow - Newport Coast CA, US
Ling Li - Irvine CA, US
Liming Wang - Irvine CA, US

Assignee:

Allergan, Inc. - Irvine CA

International Classification:

A01N 43/76
A61K 31/42
C07D 413/00
C07D 263/00

US Classification:

514377, 548233

Abstract:

Described herein are compounds that can be useful as bioactive agents. More specifically, the compounds described herein can be useful as both αand αadrenergic agonists. Methods of synthesis and administration of the compounds are also disclosed.

US Patent:

8183414, May 22, 2012

Filed:

Dec 7, 2009

Appl. No.:

12/632494

Inventors:

Ken Chow - Newport Coast CA, US
Janet A. Takeuchi - Anaheim CA, US
Ling Li - Irvine CA, US
Todd M. Heidelbaugh - Fountain Valley CA, US
Phong X. Nguyen - Placentia CA, US
Evelyn G. Corpuz - Irvine CA, US
Wenkui K Fang - Irvine CA, US
Santosh C. Sinha - Ladera Ranch CA, US
Michael E. Garst - Newport Beach CA, US

Assignee:

Allergan, Inc. - Irvine CA

International Classification:

C07C 257/00
A61K 31/155

US Classification:

564244, 514637

Abstract:

The present invention provides compounds which are N-(1-phenyl-2-arylethyl)-4,5-dihydro-2H-pyrrol-5-amine compounds and are subtype selective modulators of alpha 2B or alpha 2B and alpha 2C adrenoreceptors and are selected from the group of compounds represented by the formula.