Lisa L Gallegos

US Patent:

20210270837, Sep 2, 2021

Filed:

Mar 17, 2021

Appl. No.:

17/203832

Inventors:

- Tucson AZ, US
Aoune Barhoumi - Oro Valley AZ, US
Lisa L. Gallegos - Tucson AZ, US

International Classification:

G01N 33/574
G01N 15/14

Abstract:

Disclosed herein is a method of analyzing flow cytometry data for cells derived from homogenized whole tumor samples.

US Patent:

20200049599, Feb 13, 2020

Filed:

Apr 27, 2018

Appl. No.:

15/965786

Inventors:

- Tucson AZ, US
Aoune Barhoumi - Tucson AZ, US
Melinda Day - Oro Valley AZ, US
Lisa Gallegos - Tucson AZ, US
Katherine Leith - Tucson AZ, US
Samantha Rajkovich - Marana AZ, US
Esteban Roberts - Tucson AZ, US
Stacey Stanislaw - Tucson AZ, US
Eric Walk - Tucson AZ, US

International Classification:

G01N 1/28
A01N 1/02
G01N 33/483
G01N 1/30
G01N 1/36

Abstract:

The disclosure generally relates to the preparation of representative samples from clinical samples, e.g., tumors (whole or in part), lymph nodes, metastases, cysts, polyps, or a combination or portion thereof, using mechanical and/or biochemical dissociation methods to homogenize intact samples or large portions thereof. The resulting homogenate provides the ability to obtain a correct representative sample despite spatial heterogeneity within the sample, increasing detection likelihood of low prevalence subclones, and is suitable for use in various diagnostic assays as well as the production of therapeutics, especially “personalized” anti-tumor vaccines or immune cell based therapies.

US Patent:

20200011775, Jan 9, 2020

Filed:

Sep 16, 2019

Appl. No.:

16/571785

Inventors:

- Tucson AZ, US
Aoune Barhoumi - Oro Valley AZ, US
Lisa Gallegos - Tucson AZ, US
Stacey Stanislaw - Tucson AZ, US

International Classification:

G01N 1/40
G01N 1/28
G01N 33/574
B01L 3/00
C12Q 1/6886

Abstract:

The present disclosure provides a method of separating cellular particles from a tissue sample and then sorting the cellular particles into two or more cellular particle populations.