Lisa Huang

US Patent:

8338190, Dec 25, 2012

Filed:

Jul 30, 2012

Appl. No.:

13/561587

Inventors:

John G. Hoey - Framingham MA, US
Denise P. Dimitrov - Hamilton NJ, US
Lisa P. Huang - Princeton NJ, US
Martin E. Adelson - East Windsor NJ, US
Eli Mordechai - Robbinsville NJ, US

Assignee:

Medical Diagnostic Laboratories, LLC - Hamilton NJ

International Classification:

G01N 33/543

US Classification:

436518

Abstract:

Disclosed are two (2) proteins in the Type IV Secretion System (TIVSS) in (namely, virB10 and virB11) useful in the ELISA detection of pathogen. The recombinant expression of virB10 and virB11 and their use as kits for ELISA are also disclosed.

US Patent:

20130189715, Jul 25, 2013

Filed:

Jul 30, 2012

Appl. No.:

13/561624

Inventors:

John G. Hoey - Framingham MA, US
Denise P. Dimitrov - Hamilton NJ, US
Lisa P. Huang - Princeton NJ, US
Martin E. Adelson - East Windsor NJ, US
Eli Mordechai - Robbinsville NJ, US

Assignee:

MEDICAL DIAGNOSTIC LABORATORIES, LLC - Hamilton NJ

International Classification:

C07K 14/29
G01N 33/569

US Classification:

435 792, 530324, 4352872, 435 693

Abstract:

Disclosed is the cloning, expression and purification of a hemolysin protein and its protein fragments in . The recombinant hemolysin and its protein fragments are useful in the ELISA detection of pathogen. The use of same as a kit for ELISA is also disclosed.

US Patent:

20220347265, Nov 3, 2022

Filed:

Oct 23, 2020

Appl. No.:

17/771330

Inventors:

- Cambridge MA, US
Lisa Huang - Cambridge MA, US
Scott Lauder - Andover MA, US
Suresh Katti - Hamden CT, US
Adam Tellier - Somerville MA, US

International Classification:

A61K 38/17

Abstract:

The present disclosure provides methods for treating, preventing, or inhibiting diseases in patients having one or more CFI mutations.

US Patent:

20220241258, Aug 4, 2022

Filed:

Jul 10, 2020

Appl. No.:

17/626437

Inventors:

- Boston MA, US
Margaret S. LEE - Middleton MA, US
Gabriel Maurice BELFORT - Cambridge MA, US
Sapna Makhija GARAD - Malden MA, US
Lisa HUANG - Cambridge MA, US
Mahesh PADVAL - Cambridge MA, US
Marion WITTMANN - Medford MA, US
Randall WAGNER - Bend OR, US

Assignee:

Praxis Precision Medicines, Inc. - Boston MA

International Classification:

A61K 31/445
A61K 9/00
A61P 25/14
A61K 9/48
A61K 9/20

Abstract:

Described herein, in part, are dosage forms and compositions useful for preventing and/or treating a disease or condition relating to aberrant function of a T-type calcium channel, such as epilepsy and epilepsy syndromes (e.g., absence seizures, juvenile myoclonic epilepsy, or a genetic epilepsy), tremor (e.g., essential tremor), and psychiatric disorder (e.g., mood disorders (e.g., major depressive disorder)). The present invention further comprises methods for modulating the function of a T-type calcium channel.

US Patent:

20210371480, Dec 2, 2021

Filed:

Oct 23, 2019

Appl. No.:

17/288311

Inventors:

- Cambridge MA, US
Adarsha Koirala - Framingham MA, US
Lisa Huang - Cambridge MA, US

International Classification:

C07K 14/47
C12N 9/64
C12N 15/86
A61P 27/02

Abstract:

The present disclosure provides compositions and methods for treating, preventing, or inhibiting diseases of the eye. In one aspect, the disclosure provides recombinant CF1 adeno-associated virus (rAAV) vectors comprising a complement system gene.

US Patent:

20210006580, Jan 7, 2021

Filed:

Sep 17, 2020

Appl. No.:

17/024534

Inventors:

- Seattle WA, US
Lisa Huang - Seattle WA, US
Leonard Tracy - Seattle WA, US

International Classification:

H04L 29/06

Abstract:

The disclosure includes a method that includes receiving network traffic having a first plurality of packets that each indicate a first packet source and a first packet destination; determining an analysis host destination for each of the first plurality of packets such that the packets are distributed among a plurality of analysis hosts with communications between a given source-destination pair being sent to the same analysis host; encapsulating the first plurality of packets to generate a second plurality of encapsulated packets having the first plurality of packets as a second packet payload; and sending the second plurality of encapsulated packets to respective analysis host destinations.