Lisa Benko Rodriguez

US Patent:

20110152340, Jun 23, 2011

Filed:

May 18, 2009

Appl. No.:

12/990362

Inventors:

Eileen Emison - Princeton NJ, US
Terrye Aigeldinger DelMonte - Princeton NJ, US
Koustubh Ranade - Princeton NJ, US
Lisa Renee Rodriguez - Princeton NJ, US
Katy Lynn Moore Simonsen - Princeton NJ, US

Assignee:

BRISTOL-MYERS SQUIBB COMPANY - Princeton NJ

International Classification:

A61K 31/403
C12Q 1/68
A61P 3/10
C07H 21/04
C40B 30/04

US Classification:

514412, 435 611, 536 231, 506 9

Abstract:

The invention provides novel in vitro diagnostic methods for identifying subjects or patients who may have an increased likelihood of responding to DPP-IV inhibitor therapy. The invention also provides novel polynucleotides associated with increased responsiveness of a patient to DPP-IV inhibition. Polynucleotide fragments which comprise at least one polymorphic locus, are also provided. Allele-specific primers and probes which hybridize to these polymorphic regions, and/or which comprise at least one polymorphic locus are also provided. The polynucleotides, primers, and probes of the invention are useful in phenotype correlations, medicine, and genetic analysis.

US Patent:

20180349135, Dec 6, 2018

Filed:

Jun 4, 2018

Appl. No.:

15/997345

Inventors:

WILLIAM R. BURNS - Brick NJ, US
Joseph McGovem - Sewell NJ, US
Lisa Rodriguez - Ormond Beach FL, US
Henry Rodriguez - Ormond Beach FL, US

International Classification:

G06F 8/77
G06F 17/50

Abstract:

A method, computer program product, and computer system for receiving, at a computing device, a plurality of development requirements of a software development project. A plurality of possible results for one or more development factors estimated to complete the software development project may be generated based upon, at least in part, the plurality of development requirements for the software development project. A plurality of results for the one or more development factors estimated to complete the software development project may be generated and may include processing a different set of random values from the plurality of possible results for the one or more development factors estimated to complete the software development project during each iteration of a plurality of iterations of one or more probabilistic models. The plurality of results for the one or more development factors may be provided in a user interface.