Qi Chao - San Diego CA, US Michael J. Hadd - San Diego CA, US Mark W. Holladay - San Diego CA, US Liu Gang - San Diego CA, US Eduardo Setti - San Diego CA, US
Assignee:
Ambit Biosciences Corp. - San Diego CA
International Classification:
A61K 31/517 A61K 45/06 A61K 31/5377
US Classification:
5142345, 51426623, 51426622
Abstract:
Provided herein are quinazoline compounds for treatment of JAK kinase mediated diseases, including JAK2 kinase-, JAK3 kinase- or TYK2 kinase-mediated diseases. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and compositions.