Louise M Bergeron

US Patent:

20080145358, Jun 19, 2008

Filed:

Feb 16, 2006

Appl. No.:

11/816128

Inventors:

Sonya Zabludoff - Carlisle MA, US
Louise Bergeron - Lincoln MA, US

Assignee:

ASTRAZENECA AB - Södertälje

International Classification:

A61K 39/395
C12Q 1/48
A61K 38/02
A61P 35/02
G01N 33/53
A61K 31/7052

US Classification:

4241301, 435 15, 514 2, 514 44, 435 71

Abstract:

The invention is directed at a method for predicting a patient's responsiveness to a CHK1 inhibitor The method includes providing a sample from a test patient who is being treated with a DNA damaging agent; and determining for the presence of an activated CHK1 signal transduction pathway molecule, wherein the presence of an activated CHK1 signal transduction pathway molecule is indicative that a CHK1 inhibitor should be administered to the patient.

US Patent:

62464108, Jun 12, 2001

Filed:

Jan 19, 1996

Appl. No.:

8/588770

Inventors:

Louise M. Bergeron - Greenland NH
Mark P. Klein - Newmarket NH
Paul H. Orsillo - Kittery Pt. ME

Assignee:

International Business Machines Corp. - Armonk NY

International Classification:

G06F 1500

US Classification:

345357

Abstract:

The present invention comprises a method and system for accessing the contents of a database from an OLE enabled user application without requiring the database to be open on the users desktop or requiring the user to know a text based data manipulation language. That is, using OLE's drag and drop methodology, a user may search the contents of a database to generate a result set of rows from the database and utilize information content from the resulting rows as desired. An OLE enabled user application is opened on a user's computer. The user then selects the location of a database to be accessed using a dialogue. Once the desired database is located, a "palette" is created at a portion of the screen of the user's computer. Once the palette is created, the user then searches and accesses the contents of the database by using drag and drop gestures in conjunction with the OLE enabled user application and the established palette.