Manivannan Ethirajan

US Patent:

20140011989, Jan 9, 2014

Filed:

Jul 9, 2012

Appl. No.:

13/544558

Inventors:

Ravindra K. Pandey - East Amherst NY, US
Anurag Gupta - Hamburg NY, US
Penny Joshi - Amherst NY, US
Manivannan Ethirajan - Cheektowaga NY, US
Avinash Srivatsan - Buffalo NY, US

Assignee:

PHOTOLITEC, LLC - East Amherst NY

International Classification:

C07D 487/22
C07D 471/22

US Classification:

536 271, 540145

Abstract:

A tetrapyrrolic photosensitizer and imaging compound having a substituent other than hydrogen at its 10 carbon atom which substituent may contain a PAA nanoparticle.

US Patent:

20150329490, Nov 19, 2015

Filed:

Feb 6, 2013

Appl. No.:

14/758427

Inventors:

- Taizhou City, Zhejiang, CN
Hua BAI - Zhejiang, CN
Manivannan ETHIRAJAN - Cheektowaga NY, US
Nayan PATEL - Buffalo NY, US
Zhenliang CHEN - Zhejiang, CN

International Classification:

C07D 209/60
C07D 403/14
A61K 41/00
C09B 23/04
C07D 487/22

Abstract:

Disclosed are a cyanine dye compound and a preparation method therefor, and a dual-function agent for photodynamic therapy and a preparation method therefor. The provided cyanine dye compound is connected to multiple markers, which improves the accuracy of combination of dye and tumor cells, effectively reduces the background value, and avoids excessive residues in the liver. The provided cyanine dye compound is conjugated with the photosensitizer at 2′″ position, so that tumor highly absorbs the conjugates.

US Patent:

20150051245, Feb 19, 2015

Filed:

Nov 13, 2012

Appl. No.:

13/261870

Inventors:

- Buffalo NY, US
Ravindra K. Pandey - East Amherst NY, US
Elena V. Kurenova - West Falls NY, US
Manivannan Ethirajan - Ellicott City MD, US

International Classification:

C07D 215/38
C07D 213/74

US Classification:

514313, 514352, 546163, 546304

Abstract:

The invention relates to protein binding inhibitor compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for treating cell proliferative disorders, especially cancer.