Manzer J Durrani

US Patent:

7759338, Jul 20, 2010

Filed:

Apr 26, 2007

Appl. No.:

11/796039

Inventors:

Manzer Durrani - Scottsdale AZ, US
William B. Geiss - Athens NY, US
David J. Fairfax - Slingerlands NY, US
Dmytro O. Tymoshenko - Albany NY, US
Van-Duc Le - Selkirk NY, US
Lisa Helen Peterson - Schenectady NY, US

Assignee:

The Regents of the University of Michigan - Ann Arbor MI

International Classification:

A61K 31/5513
A61P 35/00
C07D 243/18

US Classification:

514221, 540504, 540512

Abstract:

The present invention relates to novel chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides benzodiazepine derivatives and related compounds and methods of using benzodiazepine derivatives and related compounds as therapeutic agents to treat a number of conditions associated with the faulty regulation of the processes of programmed cell death, autoimmunity, inflammation, hyperproliferation, and the like.

US Patent:

20050271711, Dec 8, 2005

Filed:

Apr 25, 2005

Appl. No.:

11/113505

Inventors:

Michael Lynch - Hollywood FL, US
Rudyard Istvan - Fort Lauderdale FL, US
Bart Chernow - Fort Lauderdale FL, US
Manzer Durrani - Plantation FL, US
Robert Pan - Cincinnati OH, US
Abel Saud - Loveland OH, US
Rosa Moese - West Chester OH, US

Assignee:

The Procter & Gamble Company - Cincinnati OH

International Classification:

A61K031/185
A61K009/70

US Classification:

424443000, 514553000

Abstract:

Therapeutic antimicrobial compositions and methods for providing enhanced immediate and residual anti-viral and antibacterial efficacy against rhinovirus, rotavirus, coronovirus, respitory syricytial virus, Gram-positive bacteria, Gram-negative bacteria and combinations thereof. More specifically, therapeutic antimicrobial compositions comprising an organic acid or organic acid mixture and a short-chain anionic surfactant having at least one of a large head group; a branched alkyl chain and an unsaturated alkyl chain, and therapeutic methods of use thereof.

US Patent:

20080312136, Dec 18, 2008

Filed:

Nov 11, 2004

Appl. No.:

10/579088

Inventors:

Manzer Durrani - Plantation FL, US
Harish Kumar - Fullerton CA, US
Timothy Krieger - Lowell MA, US
Ken Kabingue - Los Angeles CA, US
Virginia Mosher - Lebanon MO, US
Philip J. Barr - Oakland CA, US
Ian C. Bathurst - Breitenbach, AT

International Classification:

A61K 38/55
A61P 11/00

US Classification:

514 8

Abstract:

Alpha 1-antitrypsin compositions and treatment methods using such compositions for treating a variety of pulmonary diseases are provided. The compositions generally contain AAT, a stabilizing carbohydrate such as trehalose, a surfactant such as Polysorbate 80 and an antioxidant to stabilize AAT for use as a therapeutic. The formulations can be prepared as both liquids and solids and administered by nebulization of the liquid formulation or by conversion of dry powder formulation into an aerosol.

US Patent:

20090131521, May 21, 2009

Filed:

Oct 20, 2008

Appl. No.:

12/288411

Inventors:

Mitchell S. Wortzman - Scottsdale AZ, US
Manzer Durrani - Scottsdale AZ, US

International Classification:

A61K 31/327
A61K 31/19
A61P 17/10

US Classification:

514557, 514714

Abstract:

Embodiments of this invention relate to a composition containing both benzoyl peroxide and a retinoid. Additionally, it relates to the treatment of acne vulgaris by applying an aqueous gel comprising BPO and a retinoid.

US Patent:

20100286066, Nov 11, 2010

Filed:

Feb 26, 2010

Appl. No.:

12/714432

Inventors:

Manzer Durrani - Plantation FL, US
Harish Kumar - Fullerton CA, US
Timothy Krieger - Richmond TX, US
Ken Kabingue - Los Angeles CA, US
Virginia Mosher - Lebanon MO, US
Philip J. Barr - Oakland CA, US
Ian C. Bathurst - Breitenbach, AT

International Classification:

A61K 38/14
A61K 38/02
A61P 11/00

US Classification:

514 209, 514 11

Abstract:

Alpha 1-antitrypsin compositions and treatment methods using such compositions for treating a variety of pulmonary diseases are provided. The compositions generally contain AAT, a stabilizing carbohydrate such as trehalose, a surfactant such as Polysorbate 80 and an antioxidant to stabilize AAT for use as a therapeutic. The formulations can be prepared as both liquids and solids and administered by nebulization of the liquid formulation or by conversion of dry powder formulation into an aerosol.

US Patent:

20110009393, Jan 13, 2011

Filed:

Jul 19, 2010

Appl. No.:

12/838565

Inventors:

Manzer Durrani - Scottsdale AZ, US
William B. Geiss - Athens NY, US
David J. Fairfax - Slingerlands NY, US
Dmytro O. Tymoshenko - Albany NY, US
Van-Duc Le - Selkirk NY, US
Lisa H. Peterson - Schenectady NY, US

Assignee:

THE REGENTS OF THE UNIVERSITY OF MICHIGAN - Ann Arbor

International Classification:

A61K 31/5513
C07D 243/24
A61P 37/00
A61P 29/00
A61P 35/00
A61P 35/02
A61P 17/06
A61P 11/06
A61P 37/06

US Classification:

514221, 540504

Abstract:

The present invention relates to novel chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides benzodiazepine derivatives and related compounds and methods of using benzodiazepine derivatives and related compounds as therapeutic agents to treat a number of conditions associated with the faulty regulation of the processes of programmed cell death, autoimmunity, inflammation, hyperproliferation, and the like.

US Patent:

20110245238, Oct 6, 2011

Filed:

Jun 17, 2011

Appl. No.:

13/162731

Inventors:

Manzer Durrani - Scottsdale AZ, US
William B. Geiss - Athens NY, US
David J. Fairfax - Slingerlands NY, US
Dmytro O. Tymoshenko - Albany NY, US
Van-Duc Le - Selkirk NY, US
Lisa H. Peterson - Schenectady NY, US

Assignee:

THE REGENTS OF THE UNIVERSITY OF MICHIGAN - Ann Arbor MI

International Classification:

A61K 31/5513
C07D 413/12
C07D 243/24
A61P 35/00
A61P 11/06
A61P 17/06
A61P 37/06

US Classification:

514221, 540504

Abstract:

The present invention relates to novel chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides benzodiazepine derivatives and related compounds and methods of using benzodiazepine derivatives and related compounds as therapeutic agents to treat a number of conditions associated with the faulty regulation of the processes of programmed cell death, autoimmunity, inflammation, hyperproliferation, and the like.

US Patent:

20120115954, May 10, 2012

Filed:

Jan 18, 2012

Appl. No.:

13/352497

Inventors:

Mitchell S. Wortzman - Scottsdale AZ, US
Manzer Durrani - Scottsdale AZ, US

Assignee:

MEDICIS PHARMACEUTICAL CORPORATION - Scottsdale AZ

International Classification:

A61K 31/327
A61P 17/10
A61P 31/00
A61K 31/203

US Classification:

514559, 514714

Abstract:

Embodiments of this invention relate to a composition containing both benzoyl peroxide and a retinoid. Additionally, it relates to the treatment of acne vulgaris by applying an aqueous gel comprising BPO and a retinoid.