Margaret M Sherlock

US Patent:

41338871, Jan 9, 1979

Filed:

Aug 12, 1977

Appl. No.:

5/824027

Inventors:

Margaret H. Sherlock - Bloomfield NJ

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

A61K 3144
C07D21355

US Classification:

424266

Abstract:

Disclosed herein are novel 5-tritylpicolinic acids, amides, esters and pharmaceutically acceptable salts thereof. Also disclosed are methods for the use of said novel compounds as anti-acne agents.

US Patent:

41276620, Nov 28, 1978

Filed:

Aug 12, 1977

Appl. No.:

5/824029

Inventors:

Margaret H. Sherlock - Bloomfield NJ

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

A61K 3144
C07D21357

US Classification:

424266

Abstract:

Disclosed herein are novel 5-tritylpicolinic acids, amides, esters and pharmaceutically acceptable salts thereof. Also disclosed are methods for the use of said novel compounds as anti-acne agents.

US Patent:

40175006, Apr 12, 1977

Filed:

Nov 12, 1975

Appl. No.:

5/631010

Inventors:

Joseph Mayer - New York NY
Margaret H. Sherlock - Bloomfield NJ

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

C07D21374

US Classification:

2602948C

Abstract:

This invention relates to 1-amino naphthyridines prepared by a base-catalyzed condensation while in an aprotic solvent. In this condensation an o-alkyl aryl nitrile may be reacted either with the same or different o-alkyl aryl nitrile or with another nitrile. The 1-amino naphthyridines are useful as antifungal and antibacterial agents.

US Patent:

42607590, Apr 7, 1981

Filed:

Aug 14, 1978

Appl. No.:

5/933341

Inventors:

Joseph Mayer - New York NY
Margaret H. Sherlock - Bloomfield NJ

Assignee:

Schering-Corporation - Kenilworth NJ

International Classification:

C07D23920

US Classification:

544333

Abstract:

This invention relates to 1-amino naphthyridines prepared by a base-catalyzed condensation while in an aprotic solvent. In this condensation an o-alkyl aryl nitrile may be reacted either with the same or different o-alkyl aryl nitrile or with another nitrile. The 1-amino naphthyridines are useful as antifungal and antibacterial agents.

US Patent:

41153952, Sep 19, 1978

Filed:

Jan 26, 1977

Appl. No.:

5/762605

Inventors:

Joseph Mayer - New York NY
Margaret H. Sherlock - Bloomfield NJ

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

C07D48702
A01N 922

US Classification:

260296N

Abstract:

This invention relates to 1-amino naphthyridines prepared by a base-catalyzed condensation while in an aprotic solvent. In this condensation an o-alkyl aryl nitrile may be reacted either with the same or different o-alkyl aryl nitrile or with another nitrile. The 1-amino naphthyridines are useful as antifungal and antibacterial agents.

US Patent:

41384881, Feb 6, 1979

Filed:

Jan 10, 1977

Appl. No.:

5/758297

Inventors:

Margaret H. Sherlock - Bloomfield NJ
Heide Roebke - Belleville NJ

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

A61K 31455
C07D21356

US Classification:

424250

Abstract:

Disclosed herein are substituted diphenylmethyl picolinic acids, pharmaceutically acceptable salts, amides and esters thereof. The compounds disclosed are useful as topical anti-acne agents.

US Patent:

45968098, Jun 24, 1986

Filed:

Mar 25, 1985

Appl. No.:

6/716003

Inventors:

Margaret H. Sherlock - Bloomfield NJ

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

A61K 31435
A61K 31495
C07D49112

US Classification:

514293

Abstract:

Substituted 1,8-naphthyridinones are anti-allergic, anti-inflammatory and cytoprotective agents. Methods for their preparation and use are disclosed.

US Patent:

41256123, Nov 14, 1978

Filed:

Jun 20, 1977

Appl. No.:

5/807846

Inventors:

Margaret H. Sherlock - Bloomfield NJ

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

A61K 31495
C07D29518
C07D29514
C07D29508

US Classification:

424250

Abstract:

This invention relates to N-1(p-biphenylalkyl) piperazines, to the processes for making such compounds and to the use of such compounds as anti-inflammatory agents, particularly useful in the treatment of rheumatoid arthritis.