Colin Gegg - Newbury Park CA, US Eileen Johnson - Newbury Park CA, US Leslie Miranda - Thousand Oaks CA, US Kenneth Walker - Newbury Park CA, US Jerry Holder - Simi Valley CA, US Marie Wright - Westlake Village CA, US Derin D'Amico - Newbury Park CA, US
International Classification:
A61K 38/00 A61P 43/00
US Classification:
514012000
Abstract:
Disclosed is a composition of matter that involves a CGRP peptide antagonist. A pharmaceutical composition is disclosed that comprises the composition of matter and a pharmaceutically acceptable carrier, which can be configured for administration to a patient. Also disclosed is a method of producing the composition of matter. Methods of treating, preventing or mitigating migraine, are also disclosed.
Use Of Alcohol Co-Solvents To Improve Pegylation Reaction Yields
Derin C. D'Amico - Newbury Park CA, US Marie E. Wright - Westlake Village CA, US
International Classification:
A61K 38/17 A61K 38/28 A61K 38/20
US Classification:
424 852, 514 12, 514 3
Abstract:
Disclosed is a method of producing a composition of matter. The method involves obtaining a pharmacologically active peptide; and conjugating the peptide to a pharmaceutically acceptable polyethylene glycol (PEG) by reacting the peptide with a PEG-aldehyde compound at a free amine moiety on the peptide in a buffer solution comprising an alcohol co-solvent.
King George School Brandon Palestinian Territory, Occupie 1978-1980, Riverview Elementary School Brandon Palestinian Territory, Occupie 1980-1982, St. Augustine School Brandon Palestinian Territory, Occupie 1982-1984, David Livingstone Elementary School Brandon Palestinian Territory, Occupie 1984-1985, Earl Oxford Middle School Brandon Palestinian Territory, Occupie 1985-1987, Rossburn High School Rossburn Palestinian Territory, Occupie 1988-1989