Mark A Andersen

US Patent:

7153658, Dec 26, 2006

Filed:

Sep 19, 2003

Appl. No.:

10/665671

Inventors:

Mark R. Andersen - San Mateo CA, US
Michael W. Hunkapiller - San Carlos CA, US
Kenneth J. Livak - San Jose CA, US
Eugene G. Spier - Palo Alto CA, US
H. Michael Wenz - Redwood City CA, US

Assignee:

Applera Corporation - Foster City CA

International Classification:

C12Q 1/68
C07H 21/02
C07H 21/04

US Classification:

435 6, 536 231, 536 243

Abstract:

The present invention relates to methods and kits for detecting the presence or absence of (or quantitating) target nucleic acid sequences using ligation and amplification. The invention also relates to methods, reagents, and kits that employ addressable portions and labeled probes.

US Patent:

8323897, Dec 4, 2012

Filed:

Nov 26, 2003

Appl. No.:

10/723520

Inventors:

Mark R. Andersen - San Mateo CA, US
David W. Ruff - San Francisco CA, US

Assignee:

Applied Biosystems, LLC - Carlsbad CA

International Classification:

C12Q 1/68
C12P 19/34

US Classification:

435 612, 435 912

Abstract:

The present invention provides methods, reagents and kits for carrying out a variety of assays suitable for analyzing polynucleotides or samples that include an amplification step performed in a multiplex fashion. Also provided are methods for analyzing and improving the efficiency of amplification and for carrying out gene expression analysis.

US Patent:

8606606, Dec 10, 2013

Filed:

Jan 3, 2007

Appl. No.:

11/648991

Inventors:

Mark V. Andersen - Lexington MA, US

Assignee:

Vistaprint Schweiz GmbH - Winterthur

International Classification:

G06Q 40/00

US Classification:

705 711, 705 742

Abstract:

System and method for tracking and processing of text translations for online use. The adding or editing of a text element for a primary language site or a primary language promotional email automatically generates a potential translation task. Potential translation tasks are reviewed and either deleted if no translation is required or organized into groups of related translation items and submitted along with language and schedule information for translation of the primary language text into other languages for use on other language versions of the primary language site or emails. Submission of a translation group generates an automatic notification of pending translation work to the affected translators. In performing translations, the translator first selects a task group and then translates the individual tasks in the group.

US Patent:

8606607, Dec 10, 2013

Filed:

Mar 5, 2007

Appl. No.:

11/681961

Inventors:

Mark V. Andersen - Lexington MA, US

Assignee:

Vistaprint Schweiz GmbH - Winterthur

International Classification:

G06Q 40/00

US Classification:

705 711, 705 742

Abstract:

System and method for tracking and processing of text translations for online use. Translation tasks are submitted along with language and schedule information for translation of primary language text into other languages for use on other language versions of the primary language site or emails. In performing translations, the translator first selects a task group and then translates the individual tasks in the group. A translation memory retains previously translated text and associated translations. When each individual translation task is selected for translation, the translation memory is searched and previously translated identical or similar text and translations are made available for displaying to and use by the translator.

US Patent:

20040132051, Jul 8, 2004

Filed:

Jul 23, 2003

Appl. No.:

10/625436

Inventors:

Mark Andersen - San Mateo CA, US

International Classification:

C12Q001/68
C12M001/34

US Classification:

435/006000, 435/287200

Abstract:

Microfluidic devices are provided that are adapted to retain reactants in first and second chambers that can be in openable fluid communication with each other. The reactants can be reactants necessary to initiate, promote, or catalyze a polymerase chain reaction another nucleic acid sequence amplification, detection, ligation, or endonuclease reaction or a nucleic acid sequencing reaction. Methods and systems are also provided.

US Patent:

20050196392, Sep 8, 2005

Filed:

Feb 18, 2005

Appl. No.:

11/061099

Inventors:

Mark Andersen - San Mateo CA, US

International Classification:

C12Q001/68
A61K038/47

US Classification:

424094610, 435006000

Abstract:

Compositions comprising at least two polymerases, including a lesion repair polymerase, are provided. Methods for producing primer extension products using at least two polymerases, including a lesion repair polymerase, are also provided. Kits for producing primer extension products comprising at least two polymerases, including a lesion repair polymerase, are also provided.

US Patent:

20060166235, Jul 27, 2006

Filed:

Dec 15, 2005

Appl. No.:

11/303765

Inventors:

Lori Hennessy - San Mateo CA, US
Mark Andersen - Carlsbad CA, US

Assignee:

Applera Corporation - Foster City CA

International Classification:

C12Q 1/68
C12P 19/34

US Classification:

435006000, 435091200

Abstract:

The present teachings provide novel methods, compositions, and kits for forming multi-labeled polynucleotides. In some embodiments of the present teachings, multiplexed amplification reactions are performed with a plurality of primer pairs, wherein one primer in a given primer pair comprises a distinct label. Additional labeling of the resulting amplicons can be accomplished by using at least one bridge oligonucleotide to ligate a labeled tag oligonucleotide to each labeled extension product, thereby forming a plurality of multi-labeled polynucleotides. Detection of labels such as florophores and mobility modifiers in the plurality of multi-labeled polynucleotides can identify a sample. Such sample identification can be performed using a mobility dependent analysis technique such as capillary electrophoresis, and can applicable in the field of forensics.

US Patent:

20100274610, Oct 28, 2010

Filed:

Apr 23, 2009

Appl. No.:

12/428692

Inventors:

Mark V. Andersen - Lexington MA, US
Christian H. Hescock - Cambridge MA, US
Joseph I. Cohen - Cambridge MA, US
Henri B. Weinberg - Lexington MA, US
Christian M. Knott - Lowell MA, US

International Classification:

G06Q 10/00

US Classification:

705 8, 705 7

Abstract:

A computerized system, method, and computer-readable medium implementing a method for aggregating orders for items to be filled is presented. Given a plurality of received orders, a plurality of individual orders that are aggregatable based on one or more predetermined aggregation criteria are identified and aggregated into an aggregate order. Items combined in the aggregate order may be grouped into one or more fulfillment groups independently of the individual orders from which the items originated and comprising items from the aggregate order to be simultaneously filled.