Mark BLACK - Lebanon NJ, US Beth BOROWSKY - Flemington NJ, US Nancy ROGACKI - South Plainfield NJ, US Yaw SENYAH - Princeton NJ, US Rachel STEVENS - Lakewood NJ, US
The present invention discloses and claims a method of treating cognition deficits in a patient suffering from schizophrenia by administering to said patient a therapeutically effective amount of a CB1 receptor antagonist as described herein. In another aspect, this invention also discloses and claims a combination of one or more CB1 receptor antagonists and of one or more antipsychotic agents useful in the treatment of psychiatric disorders. The combination of this invention provides synergistic results in that the combination improves positive and negative symptoms of schizophrenia, weight gain and catalepsy.