Mark Edward Chapman

US Patent:

7464973, Dec 16, 2008

Filed:

Feb 4, 2003

Appl. No.:

10/358753

Inventors:

Mark Chapman - Midvale UT, US
Giovani Gongora - Spanish Fork UT, US
Roger Vale - Sandy UT, US

Assignee:

U.S. Synthetic Corporation - Orem UT

International Classification:

B25J 15/00
B66C 1/44

US Classification:

294 11, 294902, 269273

Abstract:

A traction control device and the method of making the same wherein the device has contact surfaces, typically formed from polycrystalline diamond compacts inserted into a base, and where the inserts, and in some embodiments the base, are machined or cut to induce profiles for enhanced gripping and improved wear characteristics.

US Patent:

20120053211, Mar 1, 2012

Filed:

Mar 11, 2010

Appl. No.:

13/255331

Inventors:

Mark S. Chapman - San Diego CA, US

Assignee:

ARDEA BIOSCIENCES, INC. - San Diego CA

International Classification:

A61K 31/4412
A61P 35/04
A61P 35/00
A61K 31/18
C12N 5/09

US Classification:

514347, 514601, 435375

Abstract:

The present invention relates to the field of oncology and relates to use of (S)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide or a pharmaceutically acceptable salt thereof or N-(4-(2-fluoro-4-iodophenylamino)-1,5-dimethyl-6-oxo-1,6-dihydropyridin-3-yl)cyclopropanesulfonamide or a polymorph thereof, or a pharmaceutically acceptable salt thereof, or pharmaceutical compositions comprising the same, for the preparation of a medicament for the treatment of pancreatic cancer. Further, the present invention provides methods for administering a compound disclosed herein to an individual in need thereof by administering (S)-N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide or a pharmaceutically acceptable salt thereof or N-(4-(2-fluoro-4-iodophenylamino)-1,5-dimethyl-6-oxo-1,6-dihydropyridin-3-yl)cyclopropanesulfonamide, or a polymoph thereof, or a pharmaceutically acceptable salt thereof, or pharmaceutical compositions comprising the same.

US Patent:

20120071435, Mar 22, 2012

Filed:

Mar 11, 2010

Appl. No.:

13/255278

Inventors:

Mark Chapman - San Diego CA, US

Assignee:

Ardea Biosciences, Inc. - San Diego CA

International Classification:

A61K 31/7068
A61K 31/5377
A61N 5/00
A61K 31/4188
A61K 31/436
A61P 35/00
A61K 31/517
A61K 31/165

US Classification:

514 49, 5142664, 5142345, 514575, 514393, 514291, 600 1

Abstract:

The present invention relates to the field of oncology and provides compositions and methods for treating specific cancers, including non small cell lung cancer, breast cancer, thyroid cancer, pancreatic cancer, colon cancer, melanoma, hepatoma and adenocarcinoma. Particularly, compositions and methods involving administration, either simultaneously or sequentially, of pharmaceutical combinations comprising (S)—N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide with other compounds, to patients suffering from cancer are described.

US Patent:

20120136030, May 31, 2012

Filed:

Nov 30, 2010

Appl. No.:

12/956177

Inventors:

Jeffrey MINER - San Diego CA, US
Mark Chapman - San Diego CA, US
Barry Quart - Encinitas CA, US
Alex Adjei - Williamsville NY, US
Chunrong Yu - Williamsville NY, US

International Classification:

A61K 31/4439
A61K 31/4412
A61P 35/00
A61K 31/18

US Classification:

514341, 514601, 514349

Abstract:

This invention concerns combinations of inhibitors of MEK, Raf protein kinases, and other kinases including VEGFR1-3 and PDGFR-β. This invention also concerns pharmaceutical compositions comprising the compounds described herein and methods of use of the compounds and compositions described herein, including the use in the treatment and/or prevention of cancer and other hyperproliferative disorders.

US Patent:

20130156357, Jun 20, 2013

Filed:

Mar 28, 2012

Appl. No.:

13/432224

Inventors:

S. Barrett Peterson - Orem UT, US
Jair J. Gonzalez - Provo UT, US
Kenneth E. Bertagnolli - Riverton UT, US
Debkumar Mukhopadhyay - Sandy UT, US
David P. Miess - Highland UT, US
Mark P. Chapman - Provo UT, US
Ronald W. Ward - Pleasant Grove UT, US
Nicholas Christensen - Spanish Fork UT, US
Damon B. Crockett - Mapleton UT, US
Mohammad N. Sani - Orem UT, US

Assignee:

US SYNTHETIC CORPORATION - Orem UT

International Classification:

F16C 17/04
B21K 1/04
F16C 17/02

US Classification:

384368, 384420, 384129, 29898041

Abstract:

Bearing assemblies, apparatuses, and motor assemblies using the same are disclosed. In an embodiment, a bearing assembly may include a plurality of superhard bearing elements distributed circumferentially about an axis. Each of the superhard bearing elements may include a bearing surface. At least one of the plurality of superhard bearing elements may include at least one texture feature that may be formed in a lateral surface thereof. The bearing assembly may also include a support ring that carries the superhard bearing elements.

US Patent:

20140080783, Mar 20, 2014

Filed:

Nov 18, 2013

Appl. No.:

14/082681

Inventors:

Mark CHAPMAN - San Diego CA, US

Assignee:

ARDEA BIOSCIENCES, INC. - San Diego CA

International Classification:

A61K 31/18
A61K 31/5377
A61K 31/7068
A61N 5/00
A61K 31/4188
A61K 31/436
A61K 45/06
A61K 31/517
A61K 31/185

US Classification:

514 49, 5142664, 5142345, 514575, 514393, 51426624, 514291, 600 1

Abstract:

The present invention relates to the field of oncology and provides compositions and methods for treating specific cancers, including non small cell lung cancer, breast cancer, thyroid cancer, pancreatic cancer, colon cancer, melanoma, hepatoma and adenocarcinoma. Particularly, compositions and methods involving administration, either simultaneously or sequentially, of pharmaceutical combinations comprising (S)—N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide with other compounds, to patients suffering from cancer are described.

US Patent:

56856377, Nov 11, 1997

Filed:

Sep 8, 1995

Appl. No.:

8/522989

Inventors:

Mark Garland Chapman - San Bernardino CA
Laurence Hastings Bloxham - Los Angeles CA

International Classification:

F22K 700

US Classification:

362263

Abstract:

The Dual Spectrum Illumination System (DSIS) is a modular light source having two independent emitters of optical radiation. A halogen bulb provides a high intensity visible beam. The second source of emissions is a ring of light emitting diodes (LED). The LED ring can be configured to supply area illumination, beam illumination, or a combination of area and beam illumination. The spectrum emitted by the LED is selectable from the wide range of commercially available diodes. The illumination system provides a beam and infrared area lighting using 21 high power, 6 watt, LEDs emitting at 880 nanometers mounted on the ring. Illumination control electronics are provided on a printed circuit assembly to provide the diodes with the correct current and voltage. A second embodiment of the invention is as a direct replacement for aircraft landing lights, mobile vehicle head lights, and any other situation requiring beam illumination. This embodiment of the DSIS provides high intensity beams of visible light and infrared light and is particularly suited for the U. S.

US Patent:

59844949, Nov 16, 1999

Filed:

Apr 2, 1997

Appl. No.:

8/831838

Inventors:

Mark Garland Chapman - Ontario CA
Laurence Hastings Bloxham - LaVerne CA

Assignee:

Jimmy G. Cook - Upland CA

International Classification:

F21V 1304

US Classification:

362470

Abstract:

The Dual Spectrum Illumination System (DSIS) is a modular light source having two independent emitters of optical radiation. A halogen bulb provides a high intensity visible beam. The second source of emissions is a ring of light emitting diodes (LED). The LED ring can be configured to supply area illumination, beam illumination, or a combination of area and beam illumination. The spectrum emitted by the LED is selectable from the wide range of commercially available diodes. The illumination system provides a beam and infrared area lighting using 21 high power, 6 watt, LEDs emitting at 880 nanometers mounted on the ring. Illumination control electronics are provided on a printed circuit assembly to provide the diodes with the correct current and voltage. A second embodiment of the invention is as a direct replacement for aircraft landing lights, mobile vehicle head lights, and any other situation requiring beam illumination. This embodiment of the DSIS provides high intensity beams of visible light and infrared light and is particularly suited for U. S.