Professor at UNC Charlotte, Vice President and Senior Scientific Officer at HepatoSys Inc, Board of Directors at Charlotte Folk Society
Location:
Charlotte, North Carolina Area
Industry:
Biotechnology
Work:
UNC Charlotte since Jul 1996
Professor
HepatoSys Inc - Charlotte, North Carolina Area since Aug 2005
Vice President and Senior Scientific Officer
Charlotte Folk Society - Charlotte NC since 2009
Board of Directors
Johns Hopkins School of Medicine - Baltimore MD Apr 1986 - Jul 1996
Associate Professor and Director of Research for Pediatric Surgery
Yale University School of Medicine Jan 1980 - Apr 1986
Research Scientist
Charles Y. Lee - Charlotte NC, US Mark G. Clemens - Cornelius NC, US Jian X. Zhang - Charlotte NC, US Shailendra Jain - Charlotte NC, US
Assignee:
University of North Carolina at Charlotte - Charlotte NC
International Classification:
A01N 1/00
US Classification:
435 12
Abstract:
The present invention provides a perfusion solution comprising specific metabolic agents, antioxidant agents, and membrane stabilizer agents that can help improve preservation, organ viability, and in some cases recover organs that would otherwise being unusable for transplantation. In a further embodiment, the perfusion solution can be used in combination with hypothermic machine perfusion. It has been found that combination of the perfusion solution and hypothermic machine perfusion can help prevent or reduce further damage to the organ and restore the organ's anti-oxidant system, stabilize the cellular cytoskeleton and cellular membranes, inhibit arachidonic acid pathway, provide oncotic support, reduce interstitial edema formation, and help restore energy stores within the organ. As a result, the method can be used to improve the viability of otherwise marginal donor organs.
Composition And Method For The Restoration And Preservation Of Transplant Organs Procured From Dcd Donors
Charles Y. Lee - Charlotte NC, US Mark G. Clemens - Cornelius NC, US Jian X. Zhang - Charlotte NC, US Shailendra Jain - Charlotte NC, US
International Classification:
A01N 1/02
US Classification:
435 12
Abstract:
The present invention provides a perfusion solution comprising specific metabolic agents, antioxidant agents, and membrane stabilizer agents that can help improve preservation, organ viability, and in some cases recover organs that would otherwise being unusable for transplantation. In a further embodiment, the perfusion solution can be used in combination with hypothermic machine perfusion. It has been found that combination of the perfusion solution and hypothermic machine perfusion can help prevent or reduce further damage to the organ and restore the organ's anti-oxidant system, stabilize the cellular cytoskeleton and cellular membranes, inhibit arachidonic acid pathway, provide oncotic support, reduce interstitial edema formation, and help restore energy stores within the organ. As a result, the method can be used to improve the viability of otherwise marginal donor organs.
MD Anderson Cancer Center Plastic Surgery 1515 Holcombe Blvd, Houston, TX 77030 7137941247 (phone), 7137945492 (fax)
Education:
Medical School Pennsylvania State University College of Medicine Graduated: 2004
Procedures:
Breast Reconstruction Breast Reduction
Languages:
English Spanish
Description:
Dr. Clemens graduated from the Pennsylvania State University College of Medicine in 2004. He works in Houston, TX and specializes in Plastic Surgery. Dr. Clemens is affiliated with University Of Texas MD Anderson Cancer Center.
Washington, DCChief Engineer at Boeing Past: Lead at Blue Origin, Specialist at Boeing, Lead at Sea Launch, Principal at Boeing... National Missile Defense Network Communications Chief Engineer
Blue Origin Texas Launch Site Communications Lead
Sea Launch Communications Lead
Shuttle... National Missile Defense Network Communications Chief Engineer
Blue Origin Texas Launch Site Communications Lead
Sea Launch Communications Lead
Shuttle Avionics Engineering
NASA Expendable Launch Vehicle Program Mission Comm. Integrator
Space Station Processing Facility Comm. Engineering...
Anderson Cancer Center found that silicone implants were linked to higher rates of autoimmune disorders such as scleroderma and rheumatoid arthritis than found in the general population. A leading author, Mark Clemens, said the study didnt prove cause and effect but signaled a reason for concern.
Date: Mar 25, 2019
Category: Health
Source: Google
Washington state wildfire destroys 100 homes, hundreds evacuated
The four-blaze Carlton Complex fire destroyed homes in and around the town of Pateros, about 120 miles (193 kms) northeast of Seattle, said Mark Clemens, a spokesman for the Washington Emergency Management Division.
Date: Jul 19, 2014
Source: Google
Firefighter killed battling blaze in Pacific Northwest
In neighboring Washington state, some 1,700 firefighters worked to contain two fires that have together charred 132 square miles east of the Cascade Range, destroying at least three homes and several out-buildings, said state Emergency Management Division spokesman Mark Clemens.
The state Emergency Management Division activated its operations center at Camp Murray on Wednesday to help deal with the snowstorm, but cities and counties were handling the situation on their own, said spokesman Mark Clemens. Nonetheless, representatives of the emergency division, National Guard,