Mark Allen Gregory

US Patent:

52326683, Aug 3, 1993

Filed:

Feb 27, 1991

Appl. No.:

7/661850

Inventors:

Michael E. Grant - Sand Point ID
Russell T. Gray - Brownsburg IN
Mark A. Gregory - Carmel IN
Daniel L. Kennedy - Indianapolis IN
Dino Perin - New Palestine IN
Richard Riedel - Carmel IN
Stephen D. Scopatz - Indianapolis IN
David E. Storvick - Greenwood IN

Assignee:

Boehringer Mannheim Corporation - Indianapolis IN

International Classification:

G01N 2101
G01N 2177
G01N 2178
G01N 2147

US Classification:

422 8205

Abstract:

An instrument for analyzing test strips supporting chemistries which react with a medically significant component of a body fluid to indicate the concentration of the component in the body fluid. The instrument includes a pathway along which radiation is guided from a radiation source to a strip when the strip is inserted into the instrument and along which remission is guided from the strip to a radiation detector. A title provided on the instrument provides a first remission when no strip is inserted into the instrument. The tile is separated from the radiation source by the strip when the strip is inserted into the instrument. The first remission and the strip's remission, respectively, indicate the absence and the presence of the strip in the instrument. The strip also has a surface opposite the chemistry supporting surface characterized by a second strip remission different from the first strip remission. The instrument is capable of determining whether the strip has been inserted into the instrument correctly or backward.

US Patent:

52468585, Sep 21, 1993

Filed:

Feb 27, 1991

Appl. No.:

7/661810

Inventors:

Steven R. Arbuckle - Indianapolis IN
William R. Boyd - Indianapolis IN
Michael E. Grant - Sand Point ID
Mark A. Gregory - Carmel IN
Russell T. Gray - Brownsburg IN
Friedrich Jost - Weilhein-Marnbach, DE
Daniel L. Kennedy - Indianapolis IN
Dino Perin - New Palestine IN
Richard Riedel - Carmel IN
David E. Storvick - Greenwood IN
John W. Stoughton - Indianapolis IN

Assignee:

Boehringer Mannheim Corporation - Indianapolis IN

International Classification:

G01N 3100
G01N 2100

US Classification:

436 8

Abstract:

A method and apparatus (10) for determining the remission of a chemistry (106) which reacts with a medically significant component of a body fluid. The remission of the chemistry (106) changes as it reacts. The method and apparatus (10) include irradiating the chemistry (106) with a radiation source (182), detecting remissions of radiation from the chemistry (106) with a radiation detector (300), providing a radiation pathway (164) between the source (182) and the chemistry (106), providing a remission pathway (164) between the chemistry (106) and the detector (300), and detecting the rate of change of remission of the chemistry (106) with respect to time. The irradiating, detecting and rate detecting steps and apparatus comprise initially irradiating the chemistry (106) at a first time rate and detecting remissions therefrom, comparing remission data from remission readings spaced apart by a first number of intervening remission readings, and determining when the difference between compared readings exceeds a first predetermined limit. The time rate of irradiation of the chemistry is changed once the difference between compared readings exceeds the first limit. Remission data from remission readings spaced apart by a second number of intervening remission readings are then compared.