Mark A Hayes

US Patent:

D541646, May 1, 2007

Filed:

Aug 24, 2005

Appl. No.:

29/237075

Inventors:

Mark A. Hayes - Rancho Santa Margarita CA, US
John Krsteski - Huntington Beach CA, US
William H. Dickson - Newport KY, US
Daniel M. Barczak - Cold Spring KY, US
April L. Edwards - Cincinnati OH, US

Assignee:

Targus Group International, Inc. - Anaheim CA

International Classification:

0903

US Classification:

D 9415, D9424

US Patent:

20150140069, May 21, 2015

Filed:

Sep 30, 2014

Appl. No.:

14/502836

Inventors:

- San Francisco CA, US
Wei Wen Zheng - Las Vegas NV, US
Daryl C. Drummond - Concord CA, US
Dmitri B. Kirpotin - San Francisco CA, US
Mark Eamon Hayes - San Francisco CA, US

International Classification:

A61K 9/127
A61K 48/00

US Classification:

424450, 514 44 R

Abstract:

Provided herein is a process for preparing a microparticulate complex of a particle-forming component (“PFC”) and a nucleic acid-like component (“NAC”) in a monophasic composition comprising water and a water-miscible organic solvent. Also provided is a microparticulate complex that comprises a particle-forming component complexed to a nucleic acid-like component, and a composition comprising water and the microparticulate complex. Further provided is a method of delivery of a nucleicacid-like component to a cell or to a patient by contacting the cell with or administering to the patient a composition comprising water and the microparticulate complex described herein. Still further, a charge-changing composition represented by the formula A-X—B is provided.